Search results for "elderly."
showing 10 items of 850 documents
Therapeutic management of elderly hypertensives with concomitant ischaemic heart disease.
1992
CHARACTERISTICS OF ELDERLY HYPERTENSIVES: Hypertension is most prevalent in older patients and is associated with increasing morbidity and mortality with age. Elderly hypertensives often suffer from concomitant diseases, such as ischaemic heart disease, caused by age-induced modifications to the cardiovascular system, haemodynamic function and neurohormone activity. THERAPEUTIC MANAGEMENT: Therapeutic management of elderly hypertensives with concomitant ischaemic heart disease must take account of the pharmacodynamic and pharmacokinetic changes that occur in older subjects and drugs should be selected for their efficacy in both diseases. Since elderly subjects often metabolize drugs more sl…
PROGNOSTIC VALUE OF ESTIMATED GLOMERULAR FILTRATION RATE IN HOSPITALIZED ELDERLY PATIENTS
2013
A multicenter observational study, REPOSI (REgustri POliterapie Società Italiana di Medicina Interna), was conducted to assess the prognostic value of glomerular filtration rate (eGFR) on in-hospital mortality, hospital readmission and death within 3 months, in a sample of elderly patients (n=1,363) admitted to 66 internal medicine and geriatric wards. Bases on eGFR, calculated by the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula, subjects at hostpital admission were classified into three groups: group 1 with normal eGFR (60 ml/min/1.73m2, reference group), group 2 with moderately reduced eGFR (30-59 ml/min/1.73 m2) and group 3 with severely reduced eGFR (<30 ml/m…
BIOELECTRICAL PHASE ANGLE ON HOSPITAL ADMISSION AS PREDICTOR OF SHORT- AND MIDDLE-TERM MORTALITY IN ELDERLY MEDICAL PATIENTS.
2013
QUALITY OF LIFE FOR OLDER PERSONS
2010
Joint use of cardio-embolic and bleeding risk scores in elderly patients with atrial fibrillation.
2013
In-hospital death and adverse clinical events in elderly patients according to disease clustering: the REPOSI study. Marengoni A,
2010
OBJECTIVE: The aim of the study was to recognize clusters of diseases among hospitalized elderly and to identify groups of patients at risk of in-hospital death and adverse clinical events according to disease clustering. METHOD: This was a cross-sectional study conducted in 38 internal medicine and geriatric wards in Italy participating in the Registro Politerapie SIMI (REPOSI) study during 2008. The subjects were 1,332 inpatients aged 65 years or older. Clusters of diseases (i.e., two or more co-occurrent diseases) were identified using the odds ratios (OR) for the associations between pairs of conditions, followed by cluster analysis. Logistic regression models were used to evaluate the …
Celiac disease in older persons: A case of seronegative disease
2017
A 68-year-old man with a history of smoking (former smoker of 40 cigarettes per day), euthyroid goiter, deep vein thrombosis and depression, came to our attention for weakness, cachexia, abdominal bloating and diarrhea lasting for almost six months. Furthermore, he had lost about 25 kilograms of weight in the last year and was bedridden for three months. Combining the results of serological, histopathological and genetic tests, he was diagnosed with a seronegative celiac disease. Gluten-free diet, combined with nutritional supplements and physical therapy, improved his clinical condition and allowed the recovery of weight and the walking ability. Celiac disease might be suspected in elderly…
The association of uric acid with mortality modifies at old age: data from the uric acid right for heart health (URRAH) study
2021
Objectives: In older individuals, the role of serum uric acid (SUA) as risk factor for mortality is debated. This study investigated the association of SUA with all-cause and cardiovascular (CV) mortality in older adults participating in the large multicentre observational uric acid right for heart health (URRAH) study. Methods: Eight thousand URRAH participants aged 65+ were included in the analysis. The predictive role of SUA was assessed using Cox regression models stratified according to the cut-off age of 75. SUA was tested as continuous and categorical variable (age-specific quartiles). The prognostic threshold of SUA for mortality was analysed using receiver operating characteristic …
LE IPERNATRIEMIE NELL’ANZIANO
2015
L’pernatremia è caratterizzata da un deficit di acqua corporea totale rispetto al sodio ed è definita da una concentrazione plasmatica superiore a 145 mmol/L. L’ipersodiemia nella popolazione geriatrica è un disturbo comune, associato ad una significativa morbilità e mortalità. Le persone anziane sono predisposte a sviluppare ipernatriemia a causa di modificazioni fisiologiche legate all'età: ad esempio la diminuzione della sete, una ridotta capacità di concentrazione delle urine e la diminuzione del contenuto di acqua corporea totale. I farmaci possono aumentare questa predisposizione. Nelle case di cura e di riposo, l’ipernatremia e la disidratazione sono considerate prevenibili, per cui …