Search results for "electrospun"
showing 9 items of 29 documents
Fabrication Techniques for Electrospun Polyurethane Scaffolds that Generate Valve Leaflet Mechanical Properties.
2010
A Structural Deterministic Model for Electrospun Scaffolds.
2009
Analysis of Electrospun Scaffolds Micro - Architectural Data.
2009
STRUCTURAL DETERMINISTIC MODELING DESIGN AND FABRICATION OF ELECTROSPUN SCAFFOLDS FOR SOFT TISSUE ENGINEERING
2011
The research fields of tissue engineering, biomechanics and regenerative medicine continue to evolve in response to the ever growing need for tissue replacement options. These fields aim to restore, maintain, or improve tissue or whole organ function. This doctoral studies focus on the development and experimental validation of a structural deterministic modeling strategy to: A) guide tissue engineering scaffold design, B) provide a better understanding of cellular mechanical and metabolic response to local micro-structural deformations. Targeted clinical application was the pulmonary heart valve. Electrospinning was selected as the optimal platform technology to implement, validate and tes…
Micro-Meso Scale Models of Electrosun Poly (Ester Urethane) Urea Scaffolds.
2009
Micro - Architectural Data Extraction for Electrospun Poly (Ester Urethane) Urea Scaffolds for Biomechanical Modeling.
2009
Problem: Soft tissue engineered applications have raised the need for accurate descriptions of tissue microstructure and their contributions to global mechanical behavior [1]. Accurate material image analysis is crucial to model engineered tissue biomechanics. The present study proposes a novel method to automatically collect micro-architectural data from electron micrographs (SEM) of electrospun poly (ester urethane) urea (PEUU). Methods: Sets of contiguous SEM images for electrospun PEUU scaffolds made using three mandrel collection tangential velocities (1.5, 4.5, 9.0 m/s) were analyzed. A combination of thresholding and morphological procedures enabled overlaps of fibers to be detected.…
Nexus of Electrospun Nanofibers and Additive Processing—Overview of Wearable Tactical Gears for CBRNE Defense
2021
Due to complex nature of twenty-first century battlefield, soldiers must perform multiple tasks to protect nations while maintaining their own safety. Advances in technological innovations are critical to support such functionalities to enhance safety and security. Using nexus of electrospinning and additive processing, we present how recent developments can be used to produce new generation of protective fabrics with integrative force protection, sensing/detection of chemical, biological, radiological, nuclear, and high yield explosives (CBRNE), and biomedical functionalities. Although electrospinning has been in use for some time, the special blends and configurations of nanofibers, as de…
Hyaluronan alkyl derivatives-based electrospun membranes for potential guided bone regeneration: Fabrication, characterization and in vitro osteoindu…
2020
Item does not contain fulltext The aim of the work was to determine the effects of the chemical functionalization of hyaluronic acid (HA) with pendant aliphatic tails at different lengths and free amino groups in terms of chemical reactivity, degradation rate, drug-eluting features, and surface properties when processed as electrospun membranes (EM) evaluating the osteoinductive potential for a possible application as guided bone regeneration (GBR). To this end, a series of HA derivatives with different aliphatic tails (DD-Cx mol% ≈ 12.0 mol%) and decreasing derivatization of free amino groups (DD(EDA) mol% from 70.0 to 30.0 mol%) were first synthesized, namely Hn. Then dexamethasone-loaded…
Influence of Polymer Electrospun Nanofibers on Thermal Properties of Epoxy Resins
2019
Electrospinning of polymers has gained surging interest in the last decades due to its wide range of applications in different fields, such as sensors, electronic devices, separation systems, biomedical materials. Still there are only few reports on the use of these nanofibers as reinforcement in polymer composites. In this paper, solution electrospinning was employed to produce nanofibrous mats impregnating two epoxy resins to form “monolayer“ systems, with the aim to study the influence of the nanofibers on both the curing behaviour and the morphology of the resin systems. Three polymers were chosen for producing electrospun mats, a polysulfone (PSF), a polyamide Nylon 6,6 (Ny66) and a po…