Search results for "elements"

showing 9 items of 799 documents

Pārrobežu ceļu satiksmes negadījumiem piemērojamais likums

2017

Bakalaura darba tēma ir „Pārrobežu ceļu satiksmes negadījumos piemērojamais likums”. Bakalaura darba mērķis ir noskaidrot, kādos gadījumos tiek piemērota 1971. gada 4. maija konvencija „Konvencija par ceļu satiksmes negadījumiem piemērojamo likumu” un Eiropas Parlamenta un Padomes Regula Nr. 864/2007, un kā šie divi starptautiskie normatīvie akti mijiedarbojas un atšķiras. Kā arī, izpētīt, vai tos savā praksē pielieto apdrošinātāji. Pētāmās problēmas galvenais iemesls - apdrošinātāji, nosakot atbildību un aprēķinot apdrošināšanas atlīdzību par zaudējumiem, kas cietušajām personām radušies ceļu satiksmes negadījuma rezultātā, piemēro tās valsts likumu, kurā tas noticis, nevis meklē piemēroja…

transportlīdzeklisārvalsts elementspiemērojamais likumsEiropas Parlamenta un Padomes Regula (EK) Nr. 864/2007 ( 2007. gada 11. jūlijs ) par tiesību aktiem kas piemērojami ārpuslīgumiskām saistībām sauszemes transportlīdzekļu īpašnieku civiltiesiskās atbildības obligātā apdrošināšanaceļu satiksmes negadījumsJuridiskā zinātne
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Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy

2015

ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.

transposonsequence analysispolymerase chain reactionDrug ResistanceGene DosageSettore MED/42 - Igiene Generale E Applicatabacterial proteinbeta-Lactamaseopen reading framecarbapenemasePlasmidminocyclineplasmid DNAmeropenemPharmacology (medical)geneticscolistincefpodoximeceftazidime610 Medicine & healthCarbapenemBacterialpolymyxin Btimentingene expression regulationbacteriumKlebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae3. Good healthantiinfective agentmicrobial sensitivity testKlebsiella pneumoniaeItalypriority journaltigecyclineMultipleclone (Java method)cefotaxime030106 microbiologyKlebsiella pneumoniae carbapenemase 3tobramycinMicrobial Sensitivity Testsgentamicinpiperacillin plus tazobactamchemistryGene dosageArticleMicrobiology03 medical and health sciencesComplete sequenceClone CellOpen Reading FramesertapenemBacterial Proteinsmultidrug resistanceextensively drug resistant bacteriumAnti-Bacterial AgentcefepimePharmacologylevofloxacinmicrobiologycefoxitinbiochemical phenomena metabolism and nutritionbacterial infections and mycosesVirologyAnti-Bacterial Agents; Bacterial Proteins; Carbapenems; Clone Cells; Drug Resistance Multiple Bacterial; Gene Dosage; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmids; beta-Lactamases; DNA Transposable Elements; Gene Expression Regulation Bacterial; Pharmacology (medical); Pharmacology; Infectious Diseasesantibiotic sensitivityClone CellsKlebsiella InfectionsceftriaxoneCarbapenemsbacterial genetics0301 basic medicinemolecular cloningSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeTransposition (music)Drug Resistance Multiple Bacterialpolycyclic compoundsgenetic screeningcell clonecarbapenem derivativeKlebsiella infectionunclassified drugAnti-Bacterial AgentsInfectious Diseasesbacterial genePlasmidsenzymologydoripenemBiologyminimum inhibitory concentrationbeta-Lactamasesbeta lactamaseMechanisms of ResistanceciprofloxacinAmikacin; aztreonam; carbapenemase; cefepime; cefotaxime; cefoxitin; cefpodoxime; ceftazidime; ceftriaxone; ciprofloxacin; colistin; cotrimoxazole; doripenem; doxycycline; ertapenem; gentamicin; imipenem; Klebsiella pneumoniae carbapenemase 3; levofloxacin; meropenem; minocycline; piperacillin plus tazobactam; plasmid DNA; polymyxin B; tigecycline; timentin; tobramycin; unclassified drug; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; transposon antibiotic sensitivity; Article; bacterial gene; bacterial genetics; bacterial strain; bacterium; bacterium detection; bacterium isolation; Escherichia coli; extensively drug resistant bacterium; gene dosage; genetic screening; Italy; Klebsiella pneumoniae; Klebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae; minimum inhibitory concentration; molecular cloning; nonhuman; polymerase chain reaction; priority journal; sequence analysis; cell clone; chemistry; drug effects; enzymology; gene expression regulation; genetics; isolation and purification; Klebsiella infection; Klebsiella pneumoniae; metabolism; microbial sensitivity test; microbiology; multidrug resistance; open reading frame; plasmid; transposon Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Clone Cells; DNA Transposable Elements; Drug Resistance Multiple Bacterial; Gene Dosage; Gene Expression Regulation Bacterial; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmidsplasmidbacterium isolationEscherichia coliGeneAmikacinbacterium detectionnonhumandoxycyclineisolation and purificationGene Expression Regulation Bacterialbiology.organism_classificationbacterial straincotrimoxazoleOpen reading frameDNA Transposable Elementdrug effectsDNA Transposable Elementsmetabolismaztreonamimipenem
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The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.

2021

Summary: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposable elements (TEs) are emerging as key contributors of aging and aging-related pathologies, including Alzheimer’s disease (AD) and cancer. However, the mechanisms governing heterochromatin maintenance or its relaxation in pathological conditions remain poorly understood. Here we show that PIN1, the only phosphorylation-specific cis/trans prolyl isomerase, whose loss is associated with premature aging and AD, is essential to preserve heterochromatin. We demonstrate that this PIN1 function is conserved from Drosophila to humans and prevents…

transposonsNeocortexMiceHeterochromatinProlyl isomeraseDrosophila ProteinsBiology (General)PhosphorylationRNA Small InterferingTissue homeostasisCells CulturedSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniNeuronsLamin Type BChemistryHP1phosphorylationneurodegenerationnuclear envelopePeptidylprolyl IsomeraseCell biologyDrosophila heterochromatin HP1 Lamin mechanical stress neurodegeneration nuclear envelope phosphorylation PIN1 transposonsNuclear laminaDrosophilaRNA InterferencePremature agingQH301-705.5HeterochromatinNuclear EnvelopeDrosophila; heterochromatin; HP1; Lamin; mechanical stress; neurodegeneration; nuclear envelope; phosphorylation; PIN1; transposonsSettore BIO/11 - Biologia MolecolareSettore MED/08 - Anatomia PatologicaGeneral Biochemistry Genetics and Molecular BiologyPIN1Alzheimer DiseaseSettore MED/05 - Patologia ClinicaAnimalsHumansHeterochromatin maintenancemechanical stressheterochromatinmechanical streMice Inbred C57BLNIMA-Interacting Peptidylprolyl IsomeraseChromobox Protein Homolog 5DNA Transposable ElementsHeterochromatin protein 1Stress MechanicalLaminLaminCell reports
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Evidence of Single State Dominance in the Two-Neutrino Double-β Decay of ^{82}Se with CUPID-0.

2019

We report on the measurement of the two-neutrino double-β decay of ^{82}Se performed for the first time with cryogenic calorimeters, in the framework of the CUPID-0 experiment. With an exposure of 9.95 kg yr of Zn^{82}Se, we determine the two-neutrino double-β decay half-life of ^{82}Se with an unprecedented precision level, T_{1/2}^{2ν}=[8.60±0.03(stat) _{-0.13}^{+0.19}(syst)]×10^{19}  yr. The very high signal-to-background ratio, along with the detailed reconstruction of the background sources allowed us to identify the single state dominance as the underlying mechanism of such a process, demonstrating that the higher state dominance hypothesis is disfavored at the level of 5.5σ.

two-neutrinos double-β decay; nuclear matrix elements; scintillating cryogenic calorimetersDouble beta decay exited states nuclear modelnuclear matrix elementshiukkasfysiikkaydinfysiikkatwo-neutrinos double-β decayscintillating cryogenic calorimetersPhysical review letters
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Impact of Etna’s volcanic emission on major ions and trace elements composition of the atmospheric deposition

2022

Mt. Etna, on the eastern coast of Sicily (Italy), is one of the most active volcanoes on the planet and it is widely recognized as a big source of volcanic gases (e.g., CO2 and SO2), halogens, and a lot of trace elements, to the atmosphere in the Mediterranean region. Especially during eruptive periods, Etna’s emissions can be dispersed over long distances and cover wide areas. A group of trace elements has been recently brought to attention for their possible environmental and human health impacts, the Technology-critical elements. The current knowledge about their geochemical cycles is still scarce, nevertheless, recent studies (Brugnone et al., 2020) evidenced a contribution from the vol…

volcanic emissions technology-critical elements human healthSettore GEO/08 - Geochimica E Vulcanologia
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Chemistry and fluxes of major and trace element from worldwide passive degassing volcanoes: a critical review

2015

Volcanic emissions represent one of the most important natural sources of trace elements (e.g. As, Cd, Cu, Hg, Pb, Sb, Tl and Zn) into the atmosphere, sequentially influencing the hydrosphere, lithosphere and biosphere. The human health hazard during episodic volcanic eruptions generally follows from deposition of coarse and fine particles (2.5-10 and < 2.5 μm) that produces effects such as asthma and lung and respiratory disease. Regarding passive degassing volcanoes, the harmful effects of fluorine fumigation are known both for vegetation (foliar necrosis) and human/animals (fluorosis), but only a few studies have been focused on the effects of potentially toxic trace elements. From a …

volcanic emissions trace elements fluxes environmental impactSettore GEO/08 - Geochimica E Vulcanologia
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Are the Salinelle mud volcanoes threatening human health or are anthropogenic activities threatening the Salinelle mud volcanoes?

2012

Passive samplers were used to measure the atmospheric concentrations of SO2 naturally emitted at three volcanoes in Italy (Etna, Vulcano and Stromboli) and of H2S naturally emitted at three volcanic/geothermal areas in Greece (Milos, Santorini and Nisyros). The measured concentrations and dispersion patterns varied with the strength of the source (open conduits or fumaroles), the meteorological conditions and the area topography. At Etna, Vulcano and Stromboli, SO2 concentrations reach values that are dangerous to people affected by bronchial asthma or lung diseases (>1000 μg m−3). H2S values measured at Nisyros also exceed the limit considered safe for the same group of people (>3000 μg m−…

volcanoes mosses trace elementsSettore GEO/08 - Geochimica E Vulcanologia
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Geochemical characterization of trace elements in thermomineral waters of Greece

2020

Trace elements have a fundamental role in natural and anthropogenic systems. In waters, they present a great variability of concentrations that mostly depends on the degree of gaswaterrock interactions and geochemical conditions such as pH, temperature, redox and/or exchange reactions, etc. Even though, they are present in very low contents in hostrocks, elevated concentrations in ground or surface waters may have a hazardous impact on human and animal health and thus, it is important to both quantify and try to understand their behaviour in natural systems. Here we present the results of about 300 cold and thermal mineral waters collected along the entire Hellenic territory. Physicochemica…

water geochemistry trace elements GreeceSettore GEO/08 - Geochimica E Vulcanologia
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Augājs kā pilsētvides indikators Daugavpilī

2014

Šajā promocijas darbā ir apkopoti 2006.-2013. gadā veikto pētījumu rezultāti, kuros ir analizēta vides pārveidotības pakāpe Daugavpilī. Pētījumā tiek izmantotas trīs dažādu indikatoru grupas – neofītās vaskulārās augu sugas, epifītie ķērpji un priežu miza. Neofītās augu sugas inventarizētas visos 344 pilsētas kvadrātos, lihenoindikācijas dati iegūti no 82 kvadrātiem, metālu saturs priežu mizās noteikts 50 paraugvietās. Iegūtie rezultāti liecina, ka augstākās Daugavpilī pētīto ķīmisko elementu koncentrācijas priežu mizā konstatētas industriālo objektu tuvumā, lihenoindikācijas zemākie rādītāji saistāmi ar pilsētas centrālo daļu, ko raksturo blīvs ceļu tīkls un intensīva satiksme, kā arī priv…

Ģeogrāfijaneophyte plant speciesDabas ģeogrāfijaķīmisko elementu saturs priežu mizāNatural geographycontents of chemical elements in pine barkneofītās augu sugasĢeogrāfijas un zemes zinātneslichenoindicationlihenoindikācija
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