Search results for "endocrine system"

showing 10 items of 1530 documents

23-hour observation endocrine neck surgery: lessons learned from a case series of over 1700 patients

2017

Although the surgical procedures concerning the thyroid and the parathyroid glands are considered safe, the possible occurrence of complications (mainly hematoma and hypocalcemia) limit the short stay surgery. At our institution a 23-hour-surgery with overnight hospital stay for endocrine neck surgical procedures was introduced since 2004. The present case series analyses the institutional results. Over 1913 endocrine neck surgery procedures, 1730 patients (90,2%) were managed according to this model. Among these patients, 92 suffered from hypocalcemia, 12 from airways obstruction due to the hematoma, 5 from bilateral nerve palsy. 15 more patients had unpredictable general disease compromis…

Parathyroidectomymedicine.medical_specialtyTime Factorsmedicine.medical_treatment030230 surgeryENDOCRINE SURGERY03 medical and health sciencesPostoperative Complications0302 clinical medicineHematomaTHYROIDHumansMedicineEndocrine systemMonitoring PhysiologicParathyroidectomyPostoperative Carebusiness.industryThyroidThyroidectomyLength of StaySurgical proceduresmedicine.diseaseShort stay surgerySurgeryEndocrine surgeryTreatment Outcomemedicine.anatomical_structure030220 oncology & carcinogenesisThyroidectomyOriginal Articlebusiness
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Antibiotic Prophylaxis for Thyroid and Parathyroid Surgery: A Systematic Review and Meta-analysis

2020

Objective: Although thyroid and parathyroid surgery is considered a clean procedure with a low incidence of surgical site infections (SSIs), a great number of endocrine surgeons use antibiotic prophylaxis (AP). The aim of this study was to assess whether AP is significantly effective in reducing the incidence of SSIs in this kind of surgery. Data Sources: A systematic literature search was performed with PubMed, Scopus, and ISI–Web of Science. Studies addressing the efficacy of AP in reducing the incidence of SSIs in thyroid and parathyroid surgery were included in the systematic review and meta-analysis. Review Methods: The random effects model was assumed to account for different sources …

Parathyroidectomymedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentAntibiotics030230 surgeryparathyroidectomy03 medical and health sciences0302 clinical medicinemedicineHumansSurgical Wound InfectionEndocrine systemAntibiotic prophylaxisbusiness.industryantibiotic prophylaxisIncidence (epidemiology)ThyroidThyroidectomysurgical site infectionSurgerymedicine.anatomical_structureOtorhinolaryngology030220 oncology & carcinogenesisMeta-analysisthyroidectomySurgerybusiness
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Differential Gene Expression of Medullary Thyroid Carcinoma Reveals Specific Markers Associated with Genetic Conditions

2013

Maliszewska, Agnieszka et al.

Pathologymedicine.medical_specialtyendocrine system diseasesInheritance PatternsMultiple endocrine neoplasia type 2ApoptosisBiologyGermlinePathology and Forensic MedicineThyroid carcinomaAntigens CDCell Line TumormedicineBiomarkers TumorGene silencingCluster AnalysisHumansGenetic Predisposition to DiseaseAC133 AntigenGene SilencingThyroid NeoplasmsRNA Small InterferingGlycoproteinsRegulation of gene expressionTissue microarrayReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingWnt signaling pathwaymedicine.diseaseImmunohistochemistryCarcinoma NeuroendocrineGene expression profilingGene Expression Regulation NeoplasticGene Knockdown TechniquesCancer researchPeptides
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Is the stripping technique a tissue-sparing procedure in large simple ovariancysts in children?

2008

Abstract Background Stripping of the cystic wall is performed by gynecologists to treat large ovarian cysts. Information in the pediatric population is poor. We prospectively evaluated the pathologic specimens of large ovarian cyst to determine whether the stripping technique is a tissue-sparing procedure even in this age. Methods We evaluated 5 patients. Samples were taken from the intermediate part of the cystic wall and from the layer covering the cyst during excision. The presence of ovarian tissue adjacent to the cyst wall, and the morphological features of the surrounding tissue were both evaluated. Pelvic ultrasound follow-up was also performed. Results Patients' mean age was 4.5 yea…

Pathologymedicine.medical_specialtyendocrine system diseasesOvaryovarian cystFollicular phasemedicineHumansCystProspective StudiesChildUltrasonographyOvarian cystbusiness.industrySettore MED/20 - Chirurgia Pediatrica E InfantileUltrasoundInfant NewbornInfantstrippingGeneral MedicineNewbornmedicine.diseaseOvarian CystsSerous fluidmedicine.anatomical_structureChild PreschoolPediatrics Perinatology and Child HealthFemaleSurgeryTissue sparingRadiologybusinessPediatric population
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Follicular adenoma in ectopic thyroid. A case-report

2017

Highlights • Ectopic thyroid is thyroidal tissue located far from its anatomic place. • A patient under our observation displayed left submandibular swelling. • The FNAC test report described a follicular adenoma. • Based on the FNAC diagnosis, we surgically removed the mass. • The post-operative follow-up was uneventful.

Pathologymedicine.medical_specialtyendocrine systemAdenomaendocrine system diseasesEctopic thyroid management030209 endocrinology & metabolismCase ReportPleomorphic adenoma03 medical and health sciences0302 clinical medicineParagangliomamedicineCarcinomaskin and connective tissue diseasesFibrolipomaEctopic thyroidbusiness.industryThyroidmedicine.diseaseSialadenitisbody regionsAberrant thyroid surgerymedicine.anatomical_structure030220 oncology & carcinogenesisSurgerybusinessEctopic thyroid adenomaInternational Journal of Surgery Case Reports
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Medullary Thyroid Carcinoma With Exon 2 p.L56M RET Variant: Clinical Particular Features in Two Patients

2018

RET (REarranged during Transfection) proto-oncogene variants are essential for the development of familial and sporadic forms of medullary thyroid carcinoma (MTC). The most frequent variants are usually located in exons 10, 11, and 13 through 16 of the RET gene. We report two cases of apparently sporadic MTC associated with the variant in exon 2 of RET gene. Patient 1, a 62-year old man who had undergone adrenalectomy for a 5 cm pheochromocytoma, was screened for type 2 multiple endocrine neoplasia (MEN 2) which showed elevated basal and post-intravenous calcium gluconate calcitonin levels. A fine needle aspiration biopsy (FNAB) confirmed the suspicion of MTC. The patient underwent total th…

Pathologymedicine.medical_specialtyendocrine systemMedullary cavityendocrine system diseasesEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismCase ReportL56M; Medullary thyroid carcinoma; MEN2; Pheochromocytoma; RET; Endocrinology Diabetes and Metabolismlcsh:Diseases of the endocrine glands. Clinical endocrinologyThyroid carcinomaPheochromocytoma03 medical and health sciences0302 clinical medicineEndocrinologymedullary thyroid carcinomaBiopsymedicineMultiple endocrine neoplasialcsh:RC648-665medicine.diagnostic_testbusiness.industrySettore MED/13 - ENDOCRINOLOGIAHyperplasiamedicine.diseasepheochromocytomaDiabetes and MetabolismFine-needle aspirationMEN2Calcitonin030220 oncology & carcinogenesisbusinessRETL56MFrontiers in Endocrinology
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2021 European Thyroid Association Guidelines for the Management of Iodine-Based Contrast Media-Induced Thyroid Dysfunction

2021

Given the fact that a large number of radiological examinations using iodine-based contrast media (ICM) are performed in everyday practice, clinicians should be aware of potential ICM-induced thyroid dysfunction (TD). ICM can induce hyperthyroidism (Hyper) or hypothyroidism (Hypo) due to supraphysiological concentrations of iodine in the contrast solution. The prevalence of ICM-induced TD varies from 1 to 15%. ICM-induced Hyper is predominantly found in regions with iodine deficiency and in patients with underlying nodular goiter or latent Graves’ disease. Patients at risk for ICM-induced Hypo include those with autoimmune thyroiditis, living in areas with sufficient iodine supply. Most cas…

Pediatricsmedicine.medical_specialtyGoiterHeart diseaseendocrine system diseasesEndocrinology Diabetes and MetabolismLevothyroxineGuidelinesHyperthyroidismAutoimmune thyroiditisHypothyroidismmedicinereproductive and urinary physiologyPregnancybusiness.industryContrast mediaThyroidmedicine.diseaseequipment and suppliesIodine deficiencyClinical trialmedicine.anatomical_structureembryonic structuresbusinessMultinodular goitercirculatory and respiratory physiologymedicine.drugIodine
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Outcomes of Diabetic Retinopathy Post-Bariatric Surgery in Patients with Type 2 Diabetes Mellitus

2021

Bariatric surgery is an emerging therapeutic approach for obese type 2 diabetes mellitus (T2DM) patients, with proven benefits for achieving target glucose control and even remission of diabetes. However, the effect of bariatric surgery upon diabetic retinopathy is still a subject of debate as some studies show a positive effect while others raise concerns about potential early worsening effects. We performed a systematic review, on PubMed, Science Direct, and Web of Science databases regarding the onset and progression of diabetic retinopathy in obese T2DM patients who underwent weight-loss surgical procedures. A total of 6375 T2DM patients were analyzed. Most cases remained stable after b…

Pediatricsmedicine.medical_specialtyPost bariatric surgeryendocrine system diseasesbusiness.industrytype 2 diabetes mellitusbariatric surgeryRType 2 Diabetes MellitusReviewGeneral MedicineDiabetic retinopathymedicine.diseaselaw.inventionTherapeutic approachdiabetic retinopathyBlood pressureRandomized controlled triallawDiabetes mellitusmedicineMedicineIn patientprogressionbusinessJournal of Clinical Medicine
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282 Ophtalmologic follow-up of diabetic patients managed by Gps or diabetologists: results of FOCUS survey

2011

ObjectiveTo describe the ophthalmological follow up and cardiologists-nephrologists’ involvements in diabetic patients managed by GPs or diabetologists.MethodsTransversal and observational survey conducted in 2009, by 1112 GPs and 188 specialists.Results2577 diabetic patients (T1D or T2D) have been included; 63% were males, and mean age was 62 years. Mean diabetes duration was 10 years. Most of them were hypertensive (72%), 68% had a dyslipidemia and 30% a non proliferative diabetic retinopathy. Nearly all patients have been followed by ophthalmologists (70% have been seen once a year).In patients having a diabetic retinopathy (DR), treatments have been intensified in 80% of them with a vis…

Pediatricsmedicine.medical_specialtyProteinuriaendocrine system diseasesbusiness.industrynutritional and metabolic diseasesDiabetic retinopathymedicine.diseaseBlood pressureDiabetes mellitusmedicinePhysical therapyMicroalbuminuriaObservational studyIn patientmedicine.symptomCardiology and Cardiovascular MedicinebusinessDyslipidemiaArchives of Cardiovascular Diseases Supplements
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Academic skills in children with early-onset type 1 diabetes: the effects of diabetes-related risk factors

2012

Aim  The study aimed to assess the effects of diabetes-related risk factors, especially severe hypoglycaemia, on the academic skills of children with early-onset type 1 diabetes mellitus (T1DM). Method  The study comprised 63 children with T1DM (31 females, 32 males; mean age 9y 11mo, SD 4mo) and 92 comparison children without diabetes (40 females, 52 males; mean age 9y 9mo, SD 3mo). Children were included if T1DM had been diagnosed before the age of 5 years and if they were aged between 9 and 10 years at the time of study. Children were not included if their native language was not Finnish and if they had a diagnosed neurological disorder that affected their cognitive development. Among th…

Pediatricsmedicine.medical_specialtyType 1 diabetesendocrine system diseasesDiabetic ketoacidosisnutritional and metabolic diseasesNeurological disordermedicine.diseaseSpellingDevelopmental NeuroscienceAcademic skillsDiabetes mellitusPediatrics Perinatology and Child HealthmedicineCognitive developmentNeurology (clinical)PsychologyEarly onsetDevelopmental Medicine & Child Neurology
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