Search results for "enolate"

showing 10 items of 52 documents

2015

BACKGROUND Expensive pharmaceuticals are a major reason for cost intensive health care systems. Long-term immunosuppressive therapy plays a relevant role after organ transplantation. Patents of original drugs have expired and cheaper products are available. Little data are available regarding efficacy and safety of generic immunosuppressive agents. METHODS In this prospective study, 25 patients, who were clinically stable for a minimum of 2 years after liver transplantation, were converted from the original formulations of tacrolimus (TAC) and mycophenolate mofetil to the generics Tacpan (TAP) and Mowel (MOW). Patients were followed-up for 6 months. Results were compared retrospectively to …

PharmacologyPathologymedicine.medical_specialtybusiness.industrymedicine.medical_treatmentPharmaceutical ScienceImmunosuppressionLiver transplantationMycophenolateTacrolimusMycophenolic acidOrgan transplantationInternal medicineDrug DiscoverymedicineTrough levelProspective cohort studybusinessmedicine.drugDrug Design, Development and Therapy
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Stability of mycophenolate mofetil in polypropylene 5% dextrose infusion bags and chemical compatibility associated with the use of the Equashield ® …

2019

Stability studies are necessary in healthcare settings as they facilitate fast, cost-effective and efficient work related to batch manufacturing and availability of supplies. We studied the stability of 1-10 mg/mL mycophenolate mofetil (MMF) in polypropylene 5% dextrose infusion bags prepared from Cellcept® and with a generic brand name (Micofenolato de Mofetilo Accord) at different storage temperatures. To ensure chemical compatibility during preparation, we also tested MMF sorption to the Equashield® closed-system drug transfer device used in this step. For this, a validated stability-indicating high-performance liquid chromatography method was developed for the quantification and identif…

PharmacologyPolypropyleneDrug transferChromatography010401 analytical chemistryClinical BiochemistrySorptionGeneral MedicineMycophenolateBatch manufacturing030226 pharmacology & pharmacy01 natural sciencesBiochemistryWork related0104 chemical sciencesAnalytical ChemistryChemical compatibility03 medical and health scienceschemistry.chemical_compound0302 clinical medicinechemistryDrug Discovery5 dextroseMolecular BiologyBiomedical Chromatography
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CCDC 986955: Experimental Crystal Structure Determination

2014

Related Article: Ivan I. Eliseev, Pavel V. Gushchin, Yi-An Chen, Pi-Tai Chou, Matti Haukka, Galina L. Starova, Vadim Yu. Kukushkin|2014|Eur.J.Inorg.Chem.||4101|doi:10.1002/ejic.201402364

Space GroupCrystallography(N-(NN'-Diphenylcarbamimidoyl)ethanimidamide)-(bis(pyridin-2-yl)amine)-platinum(ii) bis(246-trinitrophenolate) ethanol solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 921455: Experimental Crystal Structure Determination

2019

Related Article: Massimo Cametti, Arto Valkonen, Kai Rissanen|2019|Supramol.Chem.|31|653|doi:10.1080/10610278.2019.1632458

Space GroupCrystallographyCrystal System(22'-{12-phenylenebis[azanylylidene(E)methanylylidene]}bis{6-[([22'-bipyridin]-5-yl)methoxy]phenolate})-bis(oxido)-aqua-uranium(vi) acetonitrile solvate sesquihydrateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1978293: Experimental Crystal Structure Determination

2020

Related Article: Adrien T. Normand, Raluca Malacea-Kabbara, Rosita Lapenta, Aymeric Dajnak, Philippe Richard, Hélène Cattey, Anaëlle Bolley, Alfonso Grassi, Stefano Milione, Audrey Auffrant, Samuel Dagorne, Pierre Le Gendre|2020|Dalton Trans.|49|6989|doi:10.1039/D0DT00972E

Space GroupCrystallographyCrystal System22'-(1166-tetraphenyl-25-diazonia-16-diphosphahexa-15-diene-16-diyl)bis(46-di-t-butylphenolate) dichloromethane solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1978291: Experimental Crystal Structure Determination

2020

Related Article: Adrien T. Normand, Raluca Malacea-Kabbara, Rosita Lapenta, Aymeric Dajnak, Philippe Richard, Hélène Cattey, Anaëlle Bolley, Alfonso Grassi, Stefano Milione, Audrey Auffrant, Samuel Dagorne, Pierre Le Gendre|2020|Dalton Trans.|49|6989|doi:10.1039/D0DT00972E

Space GroupCrystallographyCrystal System22'-(1177-tetraphenyl-26-diazonia-17-diphosphahepta-16-diene-17-diyl)bis(46-di-t-butylphenolate)Crystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 2060889: Experimental Crystal Structure Determination

2021

Related Article: Lucija Ptiček, Lucija Hok, Petra Grbčić, Filip Topić, Mario Cetina, Kari Rissanen, Sandra Kraljević Pavelić, Robert Vianello, Livio Racané|2021|Org.Biomol.Chem.|19|2784|doi:10.1039/D1OB00235J

Space GroupCrystallographyCrystal System2-amino-4-(45-dihydro-1H-imidazol-3-ium-2-yl)phenolate hydrateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 209937: Experimental Crystal Structure Determination

2003

Related Article: M.Chadim, P.Diaz, E.Garcia-Espana, J.Hodacova, P.C.Junk, J.Latorre, J.M.Llinares, C.Soriano, J.Zavada|2003|New J.Chem.|27|1132|doi:10.1039/b303470d

Space GroupCrystallographyCrystal System310-Diazonia-613-diaza-1(12)-benzenacyclotetradecaphane bis(246-trinitrophenolate) acetone solvateCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1501082: Experimental Crystal Structure Determination

2017

Related Article: Ernest Graf, Jack Harrowfield, Jean-Pierre Kintzinger, Jean-Marie Lehn, Jacques Le Moigne, Kari Rissanen|2018|ChemPlusChem|83|605|doi:10.1002/cplu.201700557

Space GroupCrystallographyCrystal SystemCrystal Structure41016222732-hexaoxa-19-aza-1713-triazoniatricyclo[11.11.5.5719]tetratriacontane tris(246-trinitrophenolate) tetrahydrateCell ParametersExperimental 3D Coordinates
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CCDC 232958: Experimental Crystal Structure Determination

2005

Related Article: F.Thetiot, S.Triki, J.S.Pala, J.-R.Galan-Mascaros, J.M.Martinez-Agudo, K.R.Dunbar|2004|Eur.J.Inorg.Chem.||3783|doi:10.1002/ejic.200400203

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(mu~2~-22'-bipyrimidine)-tetrakis(22-dicyanoethoxyethenolate)-tetraaqua-di-iron(ii) dihydrateExperimental 3D Coordinates
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