Search results for "environmental-influences"

showing 5 items of 5 documents

The Older Finnish Twin Cohort : 45 Years of Follow-up

2019

AbstractThe older Finnish Twin Cohort (FTC) was established in 1974. The baseline survey was in 1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments was done in three parts, with a questionnaire study of twins born during 1945–1957 in 2011–2012, while older twins were interviewed and screened for dementia in two time periods, between 1999 and 2007 for twins born before 1938 and between 2013 and 2017 for twins born in 1938–1944. The content of these wave 4 assessments is described and some initial results are described. In addition, we have invited twin-pairs, based on response to the cohortwide surveys, to participate in detailed in-person studies; these …

0301 basic medicineMaleAgingHORMONE-REPLACEMENT THERAPYphysical activityBLOOD-PRESSURECohort Studies0302 clinical medicineSurveys and QuestionnairesTwins Dizygotickohonnut verenpaineMedicinekohorttitutkimusGenetics (clinical)FinlandBiological Specimen BanksAged 80 and overalcohol1184 Genetics developmental biology physiologyObstetrics and GynecologytwinsMiddle AgedBiobankPOPULATION-BASED TWINepigenetiikkaDEPRESSIVE SYMPTOMSCohortSKELETAL-MUSCLEFemalefyysinen aktiivisuusCohort studyAdulthypertensionAlcohol DrinkinglongitudinalPhysical activityreviewPAIRS DISCORDANTpitkittäistutkimussmokingENVIRONMENTAL-INFLUENCES03 medical and health sciencesTIME PHYSICAL-ACTIVITYtupakointiDiseases in Twinscohort studyDementiaHumansGENOME-WIDE ASSOCIATIONalkoholi (päihteet)Depressive symptomsQuestionnaire studyAgedkaksostutkimusepigeneticsbusiness.industryagingBaseline surveyTwins Monozygoticmedicine.diseasekaksoset030104 developmental biologyikääntyminenPediatrics Perinatology and Child HealthTELOMERE LENGTHbusiness030217 neurology & neurosurgeryDemographyFollow-Up Studiesdementia
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Genome-wide association scan identifies new variants associated with a cognitive predictor of dyslexia

2019

Developmental dyslexia (DD) is one of the most prevalent learning disorders, with high impact on school and psychosocial development and high comorbidity with conditions like attention-deficit hyperactivity disorder (ADHD), depression, and anxiety. DD is characterized by deficits in different cognitive skills, including word reading, spelling, rapid naming, and phonology. To investigate the genetic basis of DD, we conducted a genome-wide association study (GWAS) of these skills within one of the largest studies available, including nine cohorts of reading-impaired and typically developing children of European ancestry (N = 2562–3468). We observed a genome-wide significant effect (p < 1 × 10…

0301 basic medicineMaleCandidate geneMultifactorial InheritanceImaging geneticsQH301 BiologyLANGUAGEGenome-wide association study3124 Neurology and psychiatryCANDIDATE GENESDyslexiaCohort StudiesREADING-DISABILITYMOLECULAR-GENETICS0302 clinical medicineCognitionAUTOMATIZED NAMING RANChildSUSCEPTIBILITY LOCUSRapid automatized namingR2CSHORT-TERM-MEMORY~DC~IMAGING-GENETICSRJ Pediatrics[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesPsychiatry and Mental healthDyslexia/geneticsAnxietyFemalemedicine.symptomBDCRC0321 Neuroscience. Biological psychiatry. NeuropsychiatryClinical psychologyNeuroinformaticsAdultReading disabilityAdolescentGenotypeRJPolymorphism Single NucleotideArticlelcsh:RC321-571ENVIRONMENTAL-INFLUENCES03 medical and health sciencesCellular and Molecular NeuroscienceQH301Young AdultmedicinedysleksiaHumansGenetic Predisposition to Diseaselcsh:Neurosciences. Biological psychiatry. NeuropsychiatryBiological Psychiatrygeenitbusiness.industryDyslexiaDASmedicine.diseaseComorbiditypredictors030104 developmental biology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsRC0321DEVELOPMENTAL DYSLEXIAbusiness030217 neurology & neurosurgeryGenome-Wide Association Study
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Is harsh caregiving effective in toddlers with low inhibitory control? An experimental study in the food domain

2016

International audience; The aim of our study is to evaluate the validity of the "Caregiving x Temperament Paradigm" in the food domain. In this study, two prototypes of caregiving,control have been contrasted: Harsh (forceful measures to curve the child's behavior) versus Gentle control (supportive measures to direct the child's behavior). In food domain, the most effective control to help a child to overcome initial dislike is repeated exposure. Our first objective was to test whether the repeated exposure displayed in a gentle context has a more benefical effect on dislike shifting than the one displayed in a harsh context. Our second objective was to assess whether this effect was modera…

0301 basic medicineMale[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutritionmedia_common.quotation_subjectChild BehaviorContext (language use)effortful controlDevelopmental psychology03 medical and health sciencesFood PreferencesFeeding behaviorpreschool-childrenSurveys and QuestionnairesInhibitory controlDevelopmental and Educational PsychologyHumans0501 psychology and cognitive sciencesChild CareInhibitory controlTemperamentparental controlFood maternal feeding practicesDifficult temperamentmedia_commonEmotionChild care030109 nutrition & dieteticsexternalizing problems05 social sciencesdifficult temperamentInfantValidated questionnaireFeeding BehaviorInhibition Psychologicalvegetable consumptionCaregiversdifferential susceptibilityrepeated exposureChild PreschoolCaregivingenvironmental-influencesTemperamentFemalePsychology[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition050104 developmental & child psychologyParental control
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Genetics of Perceived Family Interaction From 12 to 17 Years of Age

2019

We analyzed how the effects of genetic and environmental factors on the perceptions of family interaction change from early to late adolescence. The data were collected by postal surveys on Finnish twins (N = 4808) at 12, 14 and 17 years of age and analyzed using genetic twin modeling. Additive genetic factors explained a modest share of the variation in perceived relational support (a2 = 0.30 in boys and 0.18 in girls) and relational tensions (a2 = 0.13 and 0.14, respectively) at 12 years of age, with the proportions becoming larger through 17 years of age (a2 = 0.53 in boys and 0.49 in girls for relational support; a2 = 0.35 in boys and 0.33 in girls for relational tensions). Simultaneous…

MaleParents0301 basic medicineCHILDHOODTwinsADULTHOODsosiaalinen vuorovaikutusAdolescentsDevelopmental psychology0302 clinical medicinenuoretSurveys and QuestionnairesTwins DizygoticadolescentsChildFinlandGenetics (clinical)media_commonOriginal ResearchHERITABILITYAge Factors1184 Genetics developmental biology physiologyLate adolescence3142 Public health care science environmental and occupational healthETIOLOGYHealth psychologyVariation (linguistics)perhesuhteetADOLESCENCE5141 SociologyFemaleFamily Relationsgeneettiset tekijätPsychologymedicine.medical_specialtyAdolescentmedia_common.quotation_subjectEnvironmentBEHAVIORSFamily interactionENVIRONMENTAL-INFLUENCES03 medical and health sciencesSex FactorsPerceptionmedicineGeneticsHumansFamilyEcology Evolution Behavior and SystematicskaksostutkimusperinnöllisyystiedePublic healthCorrectionTwins MonozygoticHeritabilityfamily interactionkaksosetBODY-MASS INDEX030104 developmental biologyEtiologyGene-Environment InteractionPerceptionBody mass index030217 neurology & neurosurgeryBehavior Genetics
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Early maturation and substance use across adolescence and young adulthood: A longitudinal study of Finnish twins.

2017

AbstractEarly maturation, indexed by pubertal development (PD), has been associated with earlier initiation and greater frequency of adolescent substance use, but this relationship may be biased by confounding factors and effects that change across development. Using a population-based Finnish twin sample (N = 3,632 individuals), we conducted twin modeling and multilevel structural equation modeling of the relationship between PD and substance use at ages 12–22. Shared environmental factors contributed to early PD and heavier substance use for females. Biological father absence was associated with early PD for boys but not girls, and did not account for the relationship between PD and subst…

Maleteini-ikäisetpubertyLongitudinal studyTwinsSocial EnvironmentDevelopmental psychologyNicotineALCOHOL-USE0302 clinical medicineDevelopmental and Educational PsychologyadolescentsLongitudinal Studiestwin studyYoung adultChildta515FATHER ABSENCEFinlandASSOCIATIONSRISKyoutheducation.field_of_studypäihteetParentingREPRODUCTIVE DEVELOPMENT05 social sciencesConfoundinglongitudinal studyta3141ta3142murrosikä3142 Public health care science environmental and occupational healthPsychiatry and Mental health5141 SociologyFemaleSMOKINGPsychologyearly pubertal development050104 developmental & child psychologymedicine.drugMediation (statistics)AdolescentAlcohol DrinkingSubstance-Related DisordersPopulationAGE 14substance usepitkittäistutkimusStructural equation modelingPeer GroupArticlePUBERTAL DEVELOPMENTENVIRONMENTAL-INFLUENCES03 medical and health sciencesYoung AdultDRINKINGIntervention (counseling)medicineDiseases in TwinsHumans0501 psychology and cognitive scienceseducationkaksostutkimusmaturationterveyskäyttäytyminen030217 neurology & neurosurgeryDevelopment and psychopathology
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