Search results for "epoc"
showing 10 items of 62 documents
Karyotype variability and inter-population genomic differences in freshwater ostracods (Crustacea) showing geographical parthenogenesis
2018
Transitions from sexual to asexual reproduction are often associated with polyploidy and increased chromosomal plasticity in asexuals. We investigated chromosomes in the freshwater ostracod species Eucypris virens (Jurine, 1820), where sexual, asexual and mixed populations can be found. Our initial karyotyping of multiple populations from Europe and North Africa, both sexual and asexual, revealed a striking variability in chromosome numbers. This would suggest that chromosomal changes are likely to be accelerated in asexuals because the constraints of meiosis are removed. Hence, we employed comparative genomic hybridization (CGH) within and among sexual and asexual populations to get insigh…
Impacto de la presencia de bronquiectasias en el pronóstico a largo plazo de pacientes con EPOC moderada-grave
2022
Diversos estudios recientemente realizados han objetivado la elevada prevalencia de bronquiectasias en pacientes con EPOC moderada-grave. En el año 2013, fue publicado por nuestro grupo de investigación el estudio que resulta ser la base de la presente tesis doctoral. En él se objetivó que dicha prevalencia fue de un 57,2%. De la misma manera se objetivó que la presencia de bronquiectasias y su gravedad estaban asociadas a un incremento de la mortalidad por todas las causas en pacientes con EPOC moderada-grave. Fue el primer estudio capaz de establecer una asociación entre la presencia de bronquiectasias y un incremento del riesgo de muerte en pacientes con EPOC. Estos resultados debían con…
From pedologic indications to archaeological reconstruction: deciphering land use in the Islamic period in the Baida district (north-western Sicily)
2013
Abstract The aim of this work was to detect imprints on soil properties from former Islamic land use (9th to 11th century) using a multi-method, soil-chemical approach. Four soil profiles (with buried horizons) found in the vicinities of former Islamic settlements in Sicily were analysed for phosphorus (total, organic and inorganic), nitrogen (total, NO 3 − and NH 4 + ), carbon compounds (δ 13 C, lipids, polycyclic aromatic hydrocarbons (PAH) and functional groups), physical and chemical C-fractions and the state of soil weathering. Two soil profiles contained ceramic sherds from the Islamic period. Inorganic nitrogen forms, phosphorous and the PAH content indicated strong impacts from trad…
Investigating the influence of climate changes on rodent communities at a regional-scale (MIS 1-3, southwestern France).
2016
25 pages; International audience; Terrestrial ecosystems have continuously evolved throughout the Late Pleistocene and theHolocene, deeply affected by both progressive environmental and climatic modifications, aswell as by abrupt and large climatic changes such as the Heinrich or Dansgaard-Oeschgerevents. Yet, the impacts of these different events on terrestrial mammalian communities arepoorly known, as is the role played by potential refugia on geographical species distributions.This study examines community changes in rodents of southwestern France between50 and 10 ky BP by integrating 94 dated faunal assemblages coming from 37 archaeologicalsites. This work reveals that faunal distributi…
B1 Was the Ancestor B Chromosome Variant in the Western Mediterranean Area in the Grasshopper Eyprepocnemis plorans.
2014
We analyzed the distribution of 2 repetitive DNAs, i.e. ribosomal DNA (rDNA) and a satellite DNA (satDNA), on the B chromosomes found in 17 natural populations of the grasshopper Eyprepocnemis plorans plorans sampled around the western Mediterranean region, including the Iberian Peninsula, Balearic Islands, Sicily, and Tunisia. Based on the amount of these repetitive DNAs, 4 types of B variants were found: B 1 , showing an equal or higher amount of rDNA than satDNA, and 3 other variants, B 2 , B 24 and B 5 , bearing a higher amount of satDNA than rDNA. The variants B 1 and B 2 varied in size among populations: B 1 was about half the size of the X chromosome in Balearic Islands, but two-thir…
Climate variation during the Holocene influenced the skeletal properties of Chamelea gallina shells in the North Adriatic Sea (Italy)
2021
Understanding how marine taxa will respond to near-future climate changes is one of the main challenges for management of coastal ecosystem services. Ecological studies that investigate relationships between the environment and shell properties of commercially important marine species are commonly restricted to latitudinal gradients or small-scale laboratory experiments. This paper aimed to explore the variations in shell features and growth of the edible bivalve Chamelea gallina from the Holocene sedimentary succession to present-day thanatocoenosis of the Po Plain-Adriatic Sea system (Italy). Comparing the Holocene sub-fossil record to modern thanatocoenoses allowed obtaining an insight o…
Un capitello tardoantico frammentario dallo scavo di Ostra
2020
Analisi di un capitello lapideo frammentario, di epoca tardoantica, rinvenuto nel corso delle moderne ricerche archeologiche nella città romana di Ostra nelle Marche
Implicación de MUC1 como marcador de corticorresistencia en la Enfermedad Pulmonar Obstructiva Crónica
2017
La mayoría de pacientes con Enfermedad Pulmonar Obstructiva Crónica (EPOC) son resistentes incluso a altas dosis de corticosteroides inhalados u orales. Han sido estudiadas varias mucinas (MUCAC y MUC5B) en las vías aéreas principales de pacientes con EPOC pero el potencial papel de MUC1 en la patología como en la aparición de corticorresistencia estaba aún por demostrar. Se conocen propiedades de MUC1 en inflamación de las vías aéreas por estar relacionada con su capacidad para inhibir varios TLR, en particular a través MyD88. Esta inhibición evita diversas cascadas de señalización, que daría lugar a la transcripción de diferentes genes pro-inflamatorios. Además MUC1 también se conoce por …
Dall’immagine all’indagine: la restituzione prospettica da foto d’epoca per la ricostruzione della chiesa di San Michele a Trapani
2022
La Chiesa di San Michele a Trapani, piccolo edificio religioso di impianto parzialmente rinascimentale, è stata demolita alla fine degli anni’50 del Novecento; di essa rimangono poche informazioni storiche e grafiche; la memoria della chiesa è oggi affidata a poche immagini fotografiche che raffigurano scroci dell’interno e di un fronte esterno. La tecnica della restituzione prospettica di foto d’epoca per la ricostruzione virtuale di edifici scomparsi è stata con successo applicata in recenti ricerche. La restituzione prospettica con metodi digitali si stacca dal piano dell’immagine per giungere, a seguito della determinazione degli schemi prospettici, alla ricostruzione tridimensionale de…
Efecto de los antagonistas de los receptores de endotelina sobre el remodelado y reactividad de la arteria pulmonar en pacientes EPOC: estudio funcio…
2015
En la presente Tesis Doctoral se tratan los efectos del bosentan, antagonista dual de los receptores de endotelina - 1, sobre la apoptosis y la expresión de receptores de endotelina inducidas por extracto de humo de cigarrillo en células endoteliales y células de músculo liso de arteria pulmonar humana. Para ello nos centramos en la importancia clínica del la combinación de dos enfermedades de las vías aéreas íntimamente relacionadas y su tratamiento conjunto (la EPOC y la Hipertensión Arterial Pulmonar severa). La hipertensión arterial pulmonar (PAH) es una complicación común de la enfermedad crónica obstructiva pulmonar (EPOC) que cursa con vasoconstricción pulmonar, producida por hipoxia…