Search results for "eps"
showing 10 items of 1777 documents
Role of biomarkers in the management of antibiotic therapy: an expert panel review II: clinical use of biomarkers for initiation or discontinuation o…
2013
Abstract Biomarker-guided initiation of antibiotic therapy has been studied in four conditions: acute pancreatitis, lower respiratory tract infection (LRTI), meningitis, and sepsis in the ICU. In pancreatitis with suspected infected necrosis, initiating antibiotics best relies on fine-needle aspiration and demonstration of infected material. We suggest that PCT be measured to help predict infection; however, available data are insufficient to decide on initiating antibiotics based on PCT levels. In adult patients suspected of community-acquired LRTI, we suggest withholding antibiotic therapy when the serum PCT level is low (<0.25 ng/mL); in patients having nosocomial LRTI, data are insuf…
The significance of the triceps surae muscle action as a determinant in the biomechanical genesis of ski fall injuries
1985
In an epidemiologic study of 700 ski fall injuries YOUNG /1/ established a classification of the different fall modes involved. In more than 60 % of all falls that lead to an injury he found a forward bending motion of the body which is frequently coupled with a twisting of the body around the lower extremity. This clearly shows the importance of the forward motion component of the skier’s body in ski fall traumatology. The type of injury and its location depend on the action of the ski binding system. If the binding does not release in a ski fall, the fraction of injuries in the lower extremity amounts to nearly 100 %. If the binding does release, however, the injuries ocurring in this cas…
Autism and Migraine: An Unexplored Association?
2020
Autism spectrum disorder is characterized by neurological, psychiatric and medical comorbidities—some conditions co-occur so frequently that comorbidity in autism is the rule rather than the exception. The most common autism co-occurring conditions are intellectual disability, language disorders, attention-deficit hyperactivity disorder, epilepsy, gastrointestinal problems, sleep disorders, anxiety, depression, obsessive-compulsive disorder, psychotic disorders, oppositional defiant disorder, and eating disorders. They are well known and studied. Migraine is the most common brain disease in the world, but surprisingly only a few studies investigate the comorbidity between autism and migrain…
Markers for gastric cancer premalignant lesions: where do we go?
2012
Only a small proportion of patients infected with <i>Helicobacter pylori</i> develop gastric cancer during their lifetime. At the same time, this type of cancer remains an important cause of mortality globally. The current interventional strategies have not been successful in decreasing the global burden of the disease; therefore, biomarkers for the identification of the individuals at high risk as well as those in the early stage of the disease is of high importance. In addition, predicting the point of no return for the development of the malignancy is of particular interest; whether atrophy, intestinal or spasmolytic polypeptide-expressing metaplasia, or some of their subtype…
Rare case of catastrophic diffuse hemorrhage complicating sepsis and meningitis due to Pasteurella stomatis in an elderly woman mimicking hemorrhagic…
2014
International audience; Cases of hemorrhagic septicemia because of Pasteurella were mainly in fallow deer, pigs, cattle, or horses generally in a tropical area where it is endemic. The infected animals present high fever, significant asthenia, diffuse hemorrhage, subcutaneous edema, hypersalivation, and diarrhea; sometimes, the disease can cause sudden death.2 The diagnosis of hemorrhagic septicemia does not refer to human beings.
A case report of double etiology of ecthyma gangrenosum
2019
Rationale Ecthyma gangrenosum is a cutaneous infection, most commonly occurring during sepsis evolution with Pseudomonas aeruginosa on an immunocompromised background. There have been rare case reports in previously healthy children and rarer are the cases with double etiology. Patient concerns We present the case of a female Caucasian patient, aged 1 year and 8 months, who developed severe sepsis during flu evolution with predominant respiratory and cerebral manifestations. On admission, at skin level, there was noticed a necrotic coccygeal ulceration (with rapid increasing dimensions 0.5/0.5 cm in 24 hours), and with the transformation from a dry necrosis in a sphacelus at the periphery a…
Twitch interpolation during equal-intensity voluntary and electrically-evoked isometric contractions of the quadriceps muscle
2005
It has been suggested that, during contractions triggered by electrical stimulation, motor units are recruited in a reversed sequence compared to voluntary contraction. The classic view is that lar...
Adjunctive Brivaracetam in Focal Epilepsy: Real-World Evidence from the BRIVAracetam add-on First Italian netwoRk STudy (BRIVAFIRST)
2021
Background: In randomized controlled trials, add-on brivaracetam (BRV) reduced seizure frequency in patients with drug-resistant focal epilepsy. Studies performed in a naturalistic setting are a useful complement to characterize the drug profile. Objective: This multicentre study assessed the effectiveness and tolerability of adjunctive BRV in a large population of patients with focal epilepsy in the context of real-world clinical practice. Methods: The BRIVAFIRST (BRIVAracetam add-on First Italian netwoRk STudy) was a retrospective, multicentre study including adult patients prescribed adjunctive BRV. Patients with focal epilepsy and 12-month follow-up were considered. Main outcomes includ…
Hospital Readmission after Major Pulmonary Resection for Lung Cancer in France: A Nationwide Medico-Administrative Database
2019
Objectives: After major pulmonary resection for lung cancer, hospital readmission is considered an indicator of the quality of care. Our main objective was to define the readmission rate at 30 days after pulmonary resection. Secondary objectives were to determine the causes and predictive factors. Methods: Data for all patients operated for lung cancer were extracted from the national medico-administrative database of the Programme de Medicalisation des Systemes d'Information (PMSI). Thirty-days hospital readmission was defined as any new hospitalization within 30 days after discharge from the surgical department following major lung resection, regardless of the reason for readmission. Resu…
Association between elastic and muscular artery stiffness and organ dysfunction in patients with early severe sepsis
2015
Sepsis is characterised by massive inflammatory response, which can affect vascular function. As part of vascular dysfunction large arteries can be affected. To what extent changes in large artery function contribute to organ dysfunction in sepsis is not well studied.