Search results for "eps"

showing 10 items of 1777 documents

Arachnoid cysts: How do postsurgical cyst size and seizure outcome correlate?

1998

Arachnoid cysts (ACs) are congenital cystic brain malformations associated with epilepsy. The purpose of this study was to determine the effect of surgical intervention of ACs on cyst size and seizure outcome. We reviewed the world's medical literature dealing with surgically treated ACs in epilepsy patients. Our study included only cases, in which the relationship between pre- and post-operative CT-size of the AC and seizure outcome was described. We also included six patients with ACs and epilepsy treated surgically at the University of Mainz. We analyzed postoperative AC size and seizure outcome with respect to mode of operation, cyst location, and patients' age. A total of 76 patients w…

AdultMalemedicine.medical_specialtyAdolescentNeurosurgical ProceduresCentral nervous system diseaseEpilepsyArachnoid cystSeizuresmedicineHumansEpilepsy surgeryCystChildbusiness.industryInfantSeizure outcomeGeneral MedicineMiddle Agedmedicine.diseaseSurgeryArachnoid CystsShuntingTreatment OutcomeChild PreschoolAnesthesiaFemaleSurgeryNeurosurgeryNeurology (clinical)Tomography X-Ray ComputedbusinessFollow-Up StudiesClinical Neurology and Neurosurgery
researchProduct

Triceps surae muscle-tendon properties in older endurance- and sprint-trained athletes

2015

Previous studies have shown that aging is associated with alterations in muscle architecture and tendon properties (Morse CI, Thom JM, Birch KM, Narici MV. Acta Physiol Scand 183: 291–298, 2005; Narici MV, Maganaris CN, Reeves ND, Capodaglio P. J Appl Physiol 95: 2229–2234, 2003; Stenroth L, Peltonen J, Cronin NJ, Sipila S, Finni T. J Appl Physiol 113: 1537–1544, 2012). However, the possible influence of different types of regular exercise loading on muscle architecture and tendon properties in older adults is poorly understood. To address this, triceps surae muscle-tendon properties were examined in older male endurance (OE, n = 10, age = 74.0 ± 2.8 yr) and sprint runners (OS, n = 10, age…

AdultMalemedicine.medical_specialtyAdolescentPhysiologyQP301.H75_Physiology._Sport.achilles tendonmechanical propertiesRunningTendonsYoung Adult03 medical and health sciences0302 clinical medicineTriceps surae muscleRegular exerciseElastic ModulusPhysiology (medical)Internal medicinemedicineHumansMuscle Skeletalta315AgedAged 80 and overSoleus muscleLegAchilles tendonAnatomy Cross-SectionalGV557_Sportsexercisebusiness.industryagingta3141030229 sport sciencesAnatomymusculoskeletal systemTendonmedicine.anatomical_structureEndocrinologySprintAthletesmuscle architecturePhysical EnduranceFascicle lengthFemalebusinessMuscle architecture030217 neurology & neurosurgeryPhysical Conditioning HumanJournal of Applied Physiology
researchProduct

Muscle strength and muscle characteristics in monozygous and dizygous twins.

1979

Muscle strength and electrical activity were investigated on 31 pairs of young male and female monozygous (MZ) and dizygous (DZ) twins. The measurements included leg forces, force-time, running velocity, muscular power, maximal integrated electromyographic activity (IEMG) and chronaximetry of the quadriceps muscle group. In each parameter the intrapair variance was computed and the differences were tested between the MZ and DZ twins. The variance ratio (MZ vs. DZ) was statistically significant only for muscular power confirming an earlier finding which has demonstrated a genetic component for the variable. In addition to the various performance variables several key enzymes involved in ATP …

AdultMalemedicine.medical_specialtyAdolescentPhysiologyTwinsElectromyographyBiologyPregnancyInternal medicinemedicineTwins DizygoticHumansChildYoung maleMuscle biopsymedicine.diagnostic_testElectromyographyMusclesQuadriceps muscleAnatomyTwins MonozygoticMuscular powerVariance ratioEndocrinologyMuscle strengthFemalemedicine.symptomEnergy MetabolismMuscle contractionMuscle ContractionActa physiologica Scandinavica
researchProduct

Levels of GHB in hair after regular application.

2021

Gamma hydroxybutyrate (GHB) is a central nervous system depressant that is an approved drug for the treatment of narcolepsy with cataplexy and other syndromes. Due to its dose dependent stimulating, relaxing or sedative effects, illicit abuses include recreational use by young people and cases of drug-facilitated crime (DFC). Since GHB is also produced endogenously, for forensic questions, it is important to be able to differentiate between endogenous GHB and elevated levels due to additional intake. In this study, we measured GHB concentrations in hair of patients with narcolepsy receiving daily GHB treatment. The results were compared to endogenous concentrations and concentrations after …

AdultMalemedicine.medical_specialtyAdolescentSodium OxybateDose dependenceRecreational use01 natural sciencesPathology and Forensic Medicine03 medical and health sciencesYoung Adult0302 clinical medicineTandem Mass SpectrometryInternal medicineMedicineHumans030216 legal & forensic medicineNarcolepsySleep disorderbusiness.industry010401 analytical chemistryCentral Nervous System DepressantsGamma hydroxybutyratemedicine.disease0104 chemical sciencesSodium saltEndocrinologySedative EffectsFemalebusinessSodium OxybateLawNarcolepsyChromatography LiquidHairForensic science international
researchProduct

Increased sensitivity of the neuronal nicotinic receptor alpha-2 subunit causes familial epilepsy with nocturnal wandering and ictal fear

2006

Sleep has traditionally been recognized as a precipitating factor for some forms of epilepsy, although differential diagnosis between some seizure types and parasomnias may be difficult. Autosomal dominant frontal lobe epilepsy is characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements and has been associated with mutations of the α4 and β2 subunits of the neuronal nicotinic acetylcholine receptor. We performed a clinical and molecular genetic study of a large pedigree segregating sleep-related epilepsy in which seizures are associated with fear sensation, tongue movements, and nocturnal wandering, closely resembling nightmares and sleep …

AdultMalemedicine.medical_specialtyAdolescentSomnambulismMolecular Sequence DataMutation MissenseAutosomal dominant nocturnal frontal lobe epilepsyReceptors NicotinicBiologymedicine.disease_causeLigandsNicotinicArticleEpilepsyBIO/09 - FISIOLOGIAInternal medicineAcetylcholine; Adolescent; Adult; Aged; Aged 80 and over; Amino Acid Sequence; Epilepsy; Female; Humans; Ligands; Male; Molecular Sequence Data; Mutation Missense; Neurons; Pedigree; Receptors Nicotinic; Somnambulism; FearReceptorsmedicine80 and overGeneticsHumansIctalGenetics(clinical)Amino Acid SequenceGenetics (clinical)Acetylcholine receptorAgedAged 80 and overNeuronsMutationEpilepsySeizure typesFearmedicine.diseaseAcetylcholinePedigreeNicotinic acetylcholine receptorNicotinic agonistEndocrinologyMutationnAChR patch-clamp ADNFLE sleep-related epilepsy M1 TM1 ACh nicotineSettore MED/26 - NeurologiaFemaleMissense
researchProduct

Serum Irisin Concentrations in Severely Inflamed Patients

2020

AbstractIrisin is a recently discovered exercise-induced myokine that has been attributed the role of favoring white-to-brown adipose tissue trans-differentiation. We confirmed in a population-based cohort that irisin serum concentrations are independently correlated with the habitual level of physical activity, but we also observed an independent correlation with serum concentrations of high-sensitivity C-reactive protein (hs-CRP), thus suggesting that inflammation may influence irisin production. In order to investigate the association between irisin and inflammation, we measured serum irisin concentrations in a group of inflamed inpatients. We hypothesized that if an association between …

AdultMalemedicine.medical_specialtyAdolescentirisin inflammation sepsis fibrinogen cytokines cachexiaEndocrinology Diabetes and MetabolismClinical BiochemistryPopulationAdipose tissue030209 endocrinology & metabolismInflammation030204 cardiovascular system & hematologyFibrinogenSeverity of Illness IndexBiochemistryCachexiaCohort StudiesYoung Adult03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyInternal medicineMyokinemedicineHumanseducationAgedAged 80 and overInflammationCreatinineeducation.field_of_studybusiness.industryBiochemistry (medical)General MedicineMiddle Agedmedicine.diseaseFibronectinsEndocrinologyItalychemistryCase-Control StudiesFemaleTumor necrosis factor alphamedicine.symptombusinessmedicine.drug
researchProduct

Mentally represented motor actions in normal aging: III. Electromyographic features of imagined arm movements.

2009

Abstract Motor imagery is a cognitive process during which subjects mentally simulate movements without actually performing them. Here, we investigated the temporal and electromyographic (EMG) features of imagined arm movements in healthy elderly adults. Twelve young (mean age: 24.0 ± 1.3 years) and 12 elderly (mean age: 67.0 ± 4.5 years) participants executed and mentally simulated, with their right and left arms and as fast and as accurately as possible, arm pointing movements between three targets located in the frontal plane. We used the mental chronometry paradigm as an indicator of the accuracy of the motor imagery process (i.e. isochrony between executed and imagined movements) and t…

AdultMalemedicine.medical_specialtyAgingTime FactorsIsochronyMovementSpatial BehaviorElectromyographyNormal agingNeuropsychological TestsBicepsDevelopmental psychologyBehavioral NeurosciencePhysical medicine and rehabilitationMotor imageryMental chronometrymedicineReaction TimeHumansAgedAnalysis of Variancemedicine.diagnostic_testElectromyographyCognitionSignal Processing Computer-AssistedImitative BehaviorCoronal planeArmImaginationFemalePsychologyPsychomotor PerformanceBehavioural brain research
researchProduct

Alcohol-related seizures may be associated with more severe depression, alcohol dependence syndrome, and more pronounced alcohol-related problems.

2018

Severe alcohol abuse and related medical and social functioning risks, as well as clinically significant depression, are common in patients who are admitted to hospital with alcohol-related seizures (ARS) and significantly affect the quality of life of the patient. Compared with studies involving patients with alcohol dependence, no large-scale studies with the aim of finding the prevalence and severity of depression and its most commonly affected aspects for patients with ARS have been carried out in Latvia yet. The habits and frequency of alcohol use in correlation to depression and its severity are also not known. One hundred ten patients were included in the study - 60 patients with ARS…

AdultMalemedicine.medical_specialtyAlcohol DrinkingPopulationAlcohol abuseAlcohol use disorderAffect (psychology)Severity of Illness IndexAlcohol Withdrawal SeizuresSuicidal Ideation03 medical and health sciencesBehavioral NeuroscienceEpilepsy0302 clinical medicinemedicineHumans030212 general & internal medicinePsychiatryeducationDepression (differential diagnoses)Agededucation.field_of_studyAlcohol Use Disorders Identification Testbusiness.industryDepressionAlcohol dependenceMiddle Agedmedicine.diseaseAlcoholismCross-Sectional StudiesNeurologyQuality of LifeFemaleNeurology (clinical)business030217 neurology & neurosurgeryEpilepsybehavior : EB
researchProduct

Muscle activation during cycling at different cadences: Effect of maximal strength capacity

2007

International audience; The purpose of this study was to examine the influence of maximal strength capacity on muscle activation, during cycling, at three selected cadences: a low cadence (50 rpm), a high cadence (110 rpm) and the freely chosen cadence (FCC). Two groups of trained cyclists were selected on the basis of the different maximal isokinetic voluntary contraction values (MVCi) of their lower extremity muscles as follow: Fmin (lower MVCi group) and Fmax (higher MVCi group). All subjects performed three 4-min cycling exercises at a power output corresponding to 80 % of the ventilatory threshold under the three cadences. Neuromuscular activity of vastus lateralis (VL), rectus femoris…

AdultMalemedicine.medical_specialtyAnaerobic ThresholdErgometryfreely chosen cadence[SHS.SPORT.PS] Humanities and Social Sciences/Sport/Sport physiologyBiophysicsNeuroscience (miscellaneous)[SHS.SPORT.PS]Humanities and Social Sciences/Sport/Sport physiologytorqueElectromyographyBiceps[ SHS.SPORT ] Humanities and Social Sciences/SportQuadriceps MusclePhysical medicine and rehabilitationOxygen ConsumptionEMGInternal medicineIsometric ContractionMaximal strengthmedicineHumansPower outputMuscle StrengthMuscle Skeletal[SHS.SPORT]Humanities and Social Sciences/Sportmedicine.diagnostic_testChemistryElectromyography[ SHS.SPORT.PS ] Humanities and Social Sciences/Sport/Sport physiology[SHS.SPORT] Humanities and Social Sciences/SportMuscle activationBicyclingBiomechanical PhenomenaLower ExtremityCardiologyPhysical EnduranceNeurology (clinical)cyclistsCadenceCyclingVentilatory thresholdforceMuscle Contraction
researchProduct

Clinical relevance of vegetation localization by transoesophageal echocardiography in infective endocarditis

1992

Infective endocarditis is associated with significant morbidity and mortality, with valvular destruction and congestive heart failure being more common in patients with echocardiographically discernible vegetations. The transoesophageal approach affords consistently high quality images with excellent structural resolution. Two-hundred and eighty-one patients with clinically suspected infective endocarditis were studied, to evaluate the prognostic value of ascertaining the site of vegetations. Among them were 118 patients with vegetations attached to the aortic or mitral valve. These patients were followed for a mean period of 14 months. Mitral valve vegetations were associated with a signif…

AdultMalemedicine.medical_specialtyAortic Valve InsufficiencyPostoperative ComplicationsSepsisStreptococcal InfectionsMitral valveInternal medicinemedicineHumansEndocarditisProspective StudiesHeart valveProspective cohort studyAbscessbusiness.industryMitral Valve InsufficiencyEndocarditis BacterialIntracranial Embolism and ThrombosisMiddle AgedStaphylococcal InfectionsPrognosismedicine.diseaseAbscessSurgerymedicine.anatomical_structureEmbolismEchocardiographyAortic ValveHeart Valve ProsthesisHeart failureInfective endocarditisCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicinebusinessEuropean Heart Journal
researchProduct