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showing 10 items of 778 documents
RabbitMash: accelerating hash-based genome analysis on modern multi-core architectures
2020
Abstract Motivation Mash is a popular hash-based genome analysis toolkit with applications to important downstream analyses tasks such as clustering and assembly. However, Mash is currently not able to fully exploit the capabilities of modern multi-core architectures, which in turn leads to high runtimes for large-scale genomic datasets. Results We present RabbitMash, an efficient highly optimized implementation of Mash which can take full advantage of modern hardware including multi-threading, vectorization and fast I/O. We show that our approach achieves speedups of at least 1.3, 9.8, 8.5 and 4.4 compared to Mash for the operations sketch, dist, triangle and screen, respectively. Furtherm…
Informe por el Cabildo eclesiastico de Valencia, Administrador general de los Diezmos de su Arzobispado, y Arcediano de Murviedro, a quienes coadyuva…
Precedeix al tít.: "Jesus, Maria y Joseph." Signat al final: "Canonigo Fabian Moros." Port. amb orla tip Caplletra ornada Sign.: [A]2, B-L2 Text a 1 col. - Notes a peu de p. - Postil·les. - Reclams
Motivos por los que los emigrantes españoles se inscriben en el registro consular
2018
La inscripción en el registro consular no es obligatoria para los emigrantes españoles. Conlleva, no obstante, una serie de ventajas que propician, antes o después, su realización. En este artículo se identifican y analizan los principales motivos que animan a ello a los emigrantes españoles. Se toman como base fundamental los datos e informaciones obtenidos a través de una encuesta cuantitativa y entrevistas semiestructuradas realizadas a más de cuatro mil españoles residentes en el extranjero. Se concluye que los principales motivos para llevar a cabo esta inscripción son los relacionados con el ejercicio de derechos y deberes ciudadanos (especialmente el de sufragio en elecciones español…
Origin of impulse initiation in the slowly adapting stretch receptor of the crayfish
1974
Characteristic for the crayfish stretch receptor is a gradual decrease in axon diameter up to a stretch of axon about 350 μm away from the soma-axon border. In response to depolarizing currents applied at different positions along the axon this stretch of axon can be localized as the most excitable membrane region. When depolarizing current steps of 10–25 nA intensity are injected into the soma the first impulse is always triggered in the soma (due to sudden rise in the membrane potential) while the second impulse originates at the axon region of highest escitability. As the intensity of the stimulus is increased the site of impulse initiation along the axon shifts nearer to the receptor so…
Production and characterization of the recombinant Sphingomonas chlorophenolica pentachlorophenol 4-monooxygenase.
2001
Abstract Pentachlorophenol 4-monooxygenase (PCP4MO) from Sphingomonas chlorophenolica is a flavoprotein that hydroxylates PCP in the presence of NADPH and oxygen. In order to investigate the structure and function of active site, recombinant PCP4MO (rePCP4MO) was produced in Escherichia coli as a glutathione S-transferase (GST) fusion protein. Moreover, a tobacco etch virus (TEV) protease cleavage site (EKLYFQG) was introduced into GST-PCP4MO and a his-tagged TEV protease was employed. Hence, a two-step purification protocol was developed which allowed obtaining 15–20 mg of rePCP4MO from 1 L culture. The rePCP4MO revealed identity with native enzyme by SDS–PAGE and N-terminal sequence analy…
A Case of Cooperative Sound Design
2016
In this design case study, protocol and linkographic analysis are applied to a task of cooperative vocal sketching, proposed in the scope of educational research activities. The understanding of the cognitive behaviors involved in sound creation is aimed at setting the ground for the development of rigorous, designerly evaluation practices tailored to sound design, all the way to the final interactive product. Relevant qualitative and quantitative information about the creative process informs the assessment and possibly improvement of sound design methods.
Triceps surae fascicle stretch is poorly correlated with short latency stretch reflex size
2015
Introduction: The short latency stretch reflex (SLR) is well described, but the stimulus that evokes the SLR remains elusive. One hypothesis states that reflex size is proportional to muscle fiber stretch, so this study examined the relationship between these 2 parameters in human triceps surae muscles. Methods: Achilles tendon taps and dorsiflexion stretches with different amplitudes and preactivation torques were applied to 6 participants while electromyography and muscle fascicle length changes were recorded in soleus and medial gastrocnemius (MG). Results: In response to tendon taps, neither fascicle length nor velocity changes were correlated with SLR size in either muscle, but acceler…
Työyhteisön teknologiavälitteinen vuorovaikutus
2020
Por la madre abadesa, y religiosas de el Convento de Santa Ana, Orden de Santa Clara de la Ciudad de Badajòz, sujetas à sus Prelados Regulares, y por…
1732
Precedeix al tít.: "Dum eclypsim patimur, novo fulgore micamus." Signat al final: "Lic. D. Andrès Rodriguez." "Lic. D. Diego Manuel Diez Coronèl." Copia de la Carta, que el ... Arzobispo de Santiago escrive al R. P. Fr. Pedro de San Juan de la Cruz, Procurador General de Padres Carmelitas Descalzos Port. amb orla, grav. xil. enmarcat de la Immaculada i altres ornaments tip Caplletra ornada, vinyeta i altres ornaments tip Sign.: [ ]1, A1, B-H2 Reclams
Influence of aging on the mechanical behavior of leg extensor muscles.
1980
Age dependence of the mechanical behavior of leg extensor muscle was investigated using vertical jumps with and without a stretch-shortening cycle on the force-platform. A total 226 subjects (113 females and 113 males) ranging in age from 4--73 years were examined. The results indicated in general that performance in males was better than that in females. This difference was reduced when body weight was taken into consideration. The peak performance of the various parameters, such as average force, height of rise of center of gravity, net impulse, and also the average power output, was reached in both sexes between the ages of 20 and 30 years. For example, the average vertical force in squa…