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showing 10 items of 778 documents

RabbitMash: accelerating hash-based genome analysis on modern multi-core architectures

2020

Abstract Motivation Mash is a popular hash-based genome analysis toolkit with applications to important downstream analyses tasks such as clustering and assembly. However, Mash is currently not able to fully exploit the capabilities of modern multi-core architectures, which in turn leads to high runtimes for large-scale genomic datasets. Results We present RabbitMash, an efficient highly optimized implementation of Mash which can take full advantage of modern hardware including multi-threading, vectorization and fast I/O. We show that our approach achieves speedups of at least 1.3, 9.8, 8.5 and 4.4 compared to Mash for the operations sketch, dist, triangle and screen, respectively. Furtherm…

Statistics and ProbabilityWorkstationExploitComputer scienceHash functionParallel computingBiochemistrylaw.invention03 medical and health sciencesSoftwarelawCluster analysisMolecular Biology030304 developmental biology0303 health sciencesMulti-core processorGenomeComputersbusiness.industry030302 biochemistry & molecular biologyGenomicsSketchComputer Science ApplicationsComputational MathematicsComputational Theory and MathematicsbusinessAlgorithmsSoftwareBioinformatics
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Informe por el Cabildo eclesiastico de Valencia, Administrador general de los Diezmos de su Arzobispado, y Arcediano de Murviedro, a quienes coadyuva…

Precedeix al tít.: "Jesus, Maria y Joseph." Signat al final: "Canonigo Fabian Moros." Port. amb orla tip Caplletra ornada Sign.: [A]2, B-L2 Text a 1 col. - Notes a peu de p. - Postil·les. - Reclams

Catedral de Valencia Judicis litigis etc. S. XVIII Obres anteriors al 1800Judicis Delmes Comunitat valenciana S. XVIII Obres anteriors al 1800Delmes Comunitat Valenciana S. XVIII Obres anteriors al 1800
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Motivos por los que los emigrantes españoles se inscriben en el registro consular

2018

La inscripción en el registro consular no es obligatoria para los emigrantes españoles. Conlleva, no obstante, una serie de ventajas que propician, antes o después, su realización. En este artículo se identifican y analizan los principales motivos que animan a ello a los emigrantes españoles. Se toman como base fundamental los datos e informaciones obtenidos a través de una encuesta cuantitativa y entrevistas semiestructuradas realizadas a más de cuatro mil españoles residentes en el extranjero. Se concluye que los principales motivos para llevar a cabo esta inscripción son los relacionados con el ejercicio de derechos y deberes ciudadanos (especialmente el de sufragio en elecciones español…

inscripciones en el Registro Civilsu realización. En este artículo se identifican y analizan los principales motivos que animan a ello a los emigrantes españoles. Se toman como base fundamental los datos e informaciones obtenidos a través de una encuesta cuantitativa y entrevistas semiestructuradas realizadas a más de cuatro mil españoles residentes en el extranjero. Se concluye que los principales motivos para llevar a cabo esta inscripción son los relacionados con el ejercicio de derechos y deberes ciudadanos (especialmente el de sufragio en elecciones españolas) y el uso de los servicios consulares más conspicuos (renovación de documentos de identidadetc.). Estos últimos juegan un papel decisivo para que acaben inscribiéndose los más reacios en principio a hacerlo. Otros motivos relevantes son los relacionados con la asistencia y protección (especialmente en países con mayores niveles de riesgo e inseguridad):SOCIOLOGÍA [UNESCO]motivosJuan Manuel La inscripción en el registro consular no es obligatoria para los emigrantes españoles. Conlleva1137-7038 8537 Arxius de sociologia 514142 2018 39 6874485 Motivos por los que los emigrantes españoles se inscriben en el registro consular Romero Valienteasí como con las ventajas fiscales y de cara al retorno a España. Emigración españolaUNESCO::SOCIOLOGÍAinscripción consularSpanish emigrationconsular registrationno obstanteuna serie de ventajas que propicianantes o despuésreasons. 37 54
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Origin of impulse initiation in the slowly adapting stretch receptor of the crayfish

1974

Characteristic for the crayfish stretch receptor is a gradual decrease in axon diameter up to a stretch of axon about 350 μm away from the soma-axon border. In response to depolarizing currents applied at different positions along the axon this stretch of axon can be localized as the most excitable membrane region. When depolarizing current steps of 10–25 nA intensity are injected into the soma the first impulse is always triggered in the soma (due to sudden rise in the membrane potential) while the second impulse originates at the axon region of highest escitability. As the intensity of the stimulus is increased the site of impulse initiation along the axon shifts nearer to the receptor so…

Membrane potentialPhysiologyChemistryVoltage clampClinical BiochemistryElectric ConductivityAstacoideaAxon hillockResting potentialAxonsAntidromicElectrophysiologymedicine.anatomical_structurenervous systemPhysiology (medical)medicineBiophysicsAnimalsSomaAxonMechanoreceptorsNeuroscienceStretch receptorPfl�gers Archiv European Journal of Physiology
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Production and characterization of the recombinant Sphingomonas chlorophenolica pentachlorophenol 4-monooxygenase.

2001

Abstract Pentachlorophenol 4-monooxygenase (PCP4MO) from Sphingomonas chlorophenolica is a flavoprotein that hydroxylates PCP in the presence of NADPH and oxygen. In order to investigate the structure and function of active site, recombinant PCP4MO (rePCP4MO) was produced in Escherichia coli as a glutathione S-transferase (GST) fusion protein. Moreover, a tobacco etch virus (TEV) protease cleavage site (EKLYFQG) was introduced into GST-PCP4MO and a his-tagged TEV protease was employed. Hence, a two-step purification protocol was developed which allowed obtaining 15–20 mg of rePCP4MO from 1 L culture. The rePCP4MO revealed identity with native enzyme by SDS–PAGE and N-terminal sequence analy…

medicine.medical_treatmentRecombinant Fusion ProteinsPotyvirusBiophysicsFlavoproteinBiochemistrySphingomonaslaw.inventionMixed Function Oxygenaseschemistry.chemical_compoundAffinity chromatographylawEndopeptidasesTEV proteasemedicineEscherichia coliAmino Acid SequenceMolecular BiologyDNA PrimersProteaseBinding SitesbiologyBase SequenceTobacco etch virusCell BiologySphingomonasbiology.organism_classificationPentachlorophenolKineticschemistryBiochemistrybiology.proteinRecombinant DNABiochemical and biophysical research communications
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A Case of Cooperative Sound Design

2016

In this design case study, protocol and linkographic analysis are applied to a task of cooperative vocal sketching, proposed in the scope of educational research activities. The understanding of the cognitive behaviors involved in sound creation is aimed at setting the ground for the development of rigorous, designerly evaluation practices tailored to sound design, all the way to the final interactive product. Relevant qualitative and quantitative information about the creative process informs the assessment and possibly improvement of sound design methods.

Settore INF/01 - InformaticaScope (project management)Computer scienceProcess (engineering)4. EducationSound design05 social sciences020207 software engineering02 engineering and technologyProduct sound designTask (project management)Design cognitionEducational researchDesign theoryHuman–computer interactionSonic interaction designSettore ICAR/13 - Disegno Industriale0202 electrical engineering electronic engineering information engineeringDesigntheory0501 psychology and cognitive sciencesSonic interaction designProtocol (object-oriented programming)Vocal sketching050107 human factorsProceedings of the 9th Nordic Conference on Human-Computer Interaction
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Triceps surae fascicle stretch is poorly correlated with short latency stretch reflex size

2015

Introduction: The short latency stretch reflex (SLR) is well described, but the stimulus that evokes the SLR remains elusive. One hypothesis states that reflex size is proportional to muscle fiber stretch, so this study examined the relationship between these 2 parameters in human triceps surae muscles. Methods: Achilles tendon taps and dorsiflexion stretches with different amplitudes and preactivation torques were applied to 6 participants while electromyography and muscle fascicle length changes were recorded in soleus and medial gastrocnemius (MG). Results: In response to tendon taps, neither fascicle length nor velocity changes were correlated with SLR size in either muscle, but acceler…

muscle fasciclereflex EMGultraäänidorsiflexion stretchtendon tapmusculoskeletal system
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Työyhteisön teknologiavälitteinen vuorovaikutus

2020

H1-99vuorovaikutusyhteisöllisyystieto- ja viestintätekniikkaCommunication. Mass mediatyöyhteisötP87-96Journalism. The periodical press etc.PN4699-5650tiimitSocial sciences (General)yhteisöviestintäLektiotdigitalisaatio
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Por la madre abadesa, y religiosas de el Convento de Santa Ana, Orden de Santa Clara de la Ciudad de Badajòz, sujetas à sus Prelados Regulares, y por…

1732

Precedeix al tít.: "Dum eclypsim patimur, novo fulgore micamus." Signat al final: "Lic. D. Andrès Rodriguez." "Lic. D. Diego Manuel Diez Coronèl." Copia de la Carta, que el ... Arzobispo de Santiago escrive al R. P. Fr. Pedro de San Juan de la Cruz, Procurador General de Padres Carmelitas Descalzos Port. amb orla, grav. xil. enmarcat de la Immaculada i altres ornaments tip Caplletra ornada, vinyeta i altres ornaments tip Sign.: [ ]1, A1, B-H2 Reclams

Judicis Jurisdicció Extremadura S.XVIII Obres anteriors al 1800Convento de Santa Ana (Badajoz) Judicis litigis etc. S.XVIII Obres anteriors al 1800Judicis Jurisdicció Extremadura S.XVIII Obres anteriors a 1800Convento de Santa Ana (Badajoz) Judicis litigis etc. S.XVIII Obres anteriors a 1800
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Influence of aging on the mechanical behavior of leg extensor muscles.

1980

Age dependence of the mechanical behavior of leg extensor muscle was investigated using vertical jumps with and without a stretch-shortening cycle on the force-platform. A total 226 subjects (113 females and 113 males) ranging in age from 4--73 years were examined. The results indicated in general that performance in males was better than that in females. This difference was reduced when body weight was taken into consideration. The peak performance of the various parameters, such as average force, height of rise of center of gravity, net impulse, and also the average power output, was reached in both sexes between the ages of 20 and 30 years. For example, the average vertical force in squa…

AdultMaleAgingAdolescentPhysiologyConcentricBiologyBody weightStretch shortening cycleSex FactorsPhysiology (medical)medicineHumansOrthopedics and Sports MedicinePower outputChildAgedOrthodonticsMusclesPublic Health Environmental and Occupational HealthGeneral MedicineAnatomyMiddle AgedElasticityVertical forceChild PreschoolReflexSquatting positionFemalemedicine.symptomMathematicsMuscle contractionMuscle ContractionEuropean journal of applied physiology and occupational physiology
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