Search results for "european Union"
showing 10 items of 1380 documents
Climate Change and Energy Issues in the North
2011
Highly industrialized societies are mostly responsible for the emerging anthropogenic climate change. There are different ways to measure this responsibility (e.g., whether based on causal contribution or strict responsibility, see Muller et al. 2007). However, regardless of the specific method applied to measure the impact, presently, the USA and the EU are the global leaders in green house gas emissions with countries such as China, India and Brazil following closely behind. Globally, GHG emissions are still increasing among the highly industrialized countries, particularly in the USA – a country that never ratified the Kyoto Protocol. However, the EU has managed to curb its emissions, co…
The application of phospholipid removal columns and ultra-high performance liquid chromatography-tandem quadrupole mass spectrometry for quantificati…
2016
In this study a robust and sensitive method based on a proposed sample purification procedure, using zirconia-coated Phree™ columns and analysis by ultra-high performance liquid chromatography with triple quadrupole tandem mass spectrometry are presented for the assessment of multi-class antibiotics in farmed fish species. The sample preparation procedure benefited from combined precipitation of proteins and selective removal of phospholipids by Phree™ columns, resulting in a high sensitivity of the method (LOQ 0.3-9mgkg(-1)). The in-house validation results (precision, repeatability, decision limit CCα, detection capability CCβ, etc.) indicate that the elaborated method is fully suitable f…
Manufacturing, characterization and control of cell-based medicinal products: challenging paradigms toward commercial use
2015
During the past decade, a large number of cell-based medicinal products have been tested in clinical trials for the treatment of various diseases and tissue defects. However, licensed products and those approaching marketing authorization are still few. One major area of challenge is the manufacturing and quality development of these complex products, for which significant manipulation of cells might be required. While the paradigms of quality, safety and efficacy must apply also to these innovative products, their demonstration may be demanding. Demonstration of comparability between production processes and batches may be difficult for cell-based medicinal products. Thus, the development …
Possible clinical usefulness of embryonic stem cells
2012
Abstract Are embryonic stem cells being used for therapeutic purposes? The aim of this short report is to review to what extent are embryonic stem cells currently used for therapeutic purposes. To the best of our knowledge, only four clinical trials have been authorised so far to use human embryonic stem cells for therapeutic purposes; two of these are included in the ClinicalTrials.gov data base, and the other two, the study sponsored by Geron and the last one initiated by Advanced Cell Technology in the United Kingdom, are not. But, in addition, Geron withdrew the clinical trial which had been originally proposed by the company itself. This brief review focuses the debate on the use of em…
Structural problems for the renewal of planning styles: the spanish case1
2005
This article first presents a historical review of Spain's involvement in the European Spatial Development Perspective (ESDP) preparation process to determine whether ESDP guidelines are different from, contrary to or in harmony with the interests of Spanish proposals. Particular attention is paid to the priority lines and territorial objectives of the Spanish delegation and its emphasis in substantive issues related to cohesion, and linking spatial planning with European Union (EU) funding. If, as the network paradigm maintains, spatial development is not possible without new methods of governance, our work has to focus on two related questions. The first question regards the evolution and…
Packing a Trunk
2003
We report on a project with a German car manufacturer. The task is to compute (approximate) solutions to a specific large-scale packing problem. Given a polyhedral model of a car trunk, the aim is to pack as many identical boxes of size 4 × 2 × 1 units as possible into the interior of the trunk. This measure is important for car manufacturers, because it is a standard in the European Union.
Modeling the Probability of Informed Trading in the European Carbon Market
2012
We provide evidence of informed trading in the European carbon market. We adapt Easley et al.’s (1996) PIN methodology to the particularities of this market by isolating the trading activity on the two carbon offsets: European Union Allowances (EUAs) and Certified Emission Reductions (CERs). We find that the PIN regularly increases before the publication of the yearly verified-emission reports. CERs exhibit lower average PIN than EUAs. While the PIN of CERs has increased over time, together with its share in total trading activity, EUAs’ PIN has remained pretty stable. Our findings suggest that CERs must not be avoided in any decision or analysis made by researchers, regulators or traders i…
Intraday Price Dynamics between EUAs and CERs in the European Carbon Futures Market
2011
We provide the first intraday analysis on the contribution to price discovery of two emissions carbon credits: European Union Allowances (EUAs) and Certified Emission Reductions (CERs). We find that EUAs lead price discovery but CERs play a growing role and, therefore, should not be ignored.
Assessing the Enlargement and Deepening of the European Union
2008
This paper estimates a theoreticallymotivated gravity model to examine the effect of the European Union (EU) on trade and whet her the order of entry has affected the trade performance of member countries. Additionally, we analyse the impact of the diffe rent phases of EU integration on trade. The results show that both original countries and successive enlargements boost intra-b loc trade. Moreover, the results suggest that the deepening in the integration process has led to more trade creation among members. Finally, only the latter ph ase of the European integration process (the single currency) has increased trade with non-members.
Public Support for TTIP in EU Countries: What Determines Trade Policy Preferences in a Salient Real-World Case?
2016
Attitudes towards international economic integration are usually measured via survey questions on preferences for free trade in general, arguably in contexts of low salience of international economic integration in the public mind. Drawing on three recent rounds of Eurobarometer surveys that contain information on citizens’ attitudes towards a free trade and investment agreement between the EU and the USA, this paper seizes the opportunity to re-examine individual-level preferences towards international economic integration with regard to a specific real-world case of relatively high political salience, i.e. TTIP. While past research has explained preferences towards trade primarily via mod…