Search results for "events"
showing 10 items of 514 documents
Epistemic uncertainty in fault tree analysis approached by the evidence theory
2012
Abstract Process plants may be subjected to dangerous events. Different methodologies are nowadays employed to identify failure events, that can lead to severe accidents, and to assess the relative probability of occurrence. As for rare events reliability data are generally poor, leading to a partial or incomplete knowledge of the process, the classical probabilistic approach can not be successfully used. Such an uncertainty, called epistemic uncertainty, can be treated by means of different methodologies, alternative to the probabilistic one. In this work, the Evidence Theory or Dempster–Shafer theory (DST) is proposed to deal with this kind of uncertainty. In particular, the classical Fau…
Rainfall timing and runoff: The influence of the criterion for rain event separation
2016
Abstract Rain is not uniform in time and space in semiarid areas and its distribution is very important for the runoff process. Hydrological studies usually divide rainfall into events. However, defining rain events is complicated, and rain characteristics vary depending on how the events are delimited. Choosing a minimum inter-event time (MIT) is a commonly used criterion. Our hypothesis is that there will be an optimal MIT that explains the maximum part of the variance of the runoff, with time to runoff used as a surrogate. The objective is to establish a procedure in order to decide upon this optimal MIT. We developed regressions between time to runoff (T0) and three descriptive variable…
Organizational commitment and its effects on organizational citizenship behavior in a high-unemployment environment
2016
[EN] Organizational commitment is an important concept in management and a construct on which extensive research exists. This study considers the relationship of the three dimensions of organizational commitment (affective, normative, and continuance commitment) with employees' organizational citizenship behavior in a high-unemployment environment. By analyzing the effect of high unemployment on the displacement of the self-concept from individual toward relational and collective levels, this work predicts differences in the effect of unemployment on each of the organizational-commitment dimensions. The results show that in a high-unemployment environment the affective and normative dimensi…
FUNCTIONAL NONRETENTIVE FECAL SOILING AND STRESSFUL LIFE EVENTS
2019
Introduction: Functional non-retentive fecal soiling (FNRFS), or encopresis without constipation, is a common problem in pediatric age. FNRFS is associated with high levels of distress for both children and parents and with emotional disorders in about 30%-50% of affected children. This study aimed to evaluate stressors on a sample of children with FNRFS comparing to a group of typical devolpment children (TDC). Methods:154 subjects participated in the study: 56 FNRFS children (37 males; mean age 10.87 years ± 1.68); 98 TDC (65 males; mean age 11.3 years ± 1.85). All participants were evaluated for the presence of stressful events (LCU) using the Coddington Life Events Scales (CLES). Result…
A Prospective Open-Label Observational Study of a Buffered Soluble 70 mg Alendronate Effervescent Tableton Upper Gastrointestinal Safety and Medicati…
2021
Upper gastrointestinal (GI) side effects are a main reason for discontinuing bisphosphonate treatment, an important therapeuticoption for osteoporosis patients. Consequently, the development of novel formulations with improved tolerability is warranted. Inthis multicenter prospective, observational, postauthorization safety study conducted in Italy and Spain, postmenopausal women(PMW) with osteoporosis (naïve to bisphosphonates) were treated weekly with a buffered soluble alendronate 70 mg effervescent(ALN-EFF) tablet (Binosto®) and followed for 12 3 months. Information was collected on adverse events (AEs), medication errors,persistence, and compliance using the Morisky-Green questionnai…
A Prospective Open‐Label Observational Study of a Buffered Soluble 70 mg Alendronate Effervescent Tablet on Upper Gastrointestinal Safety and Medicat…
2021
Upper gastrointestinal (GI) side effects are a main reason for discontinuing bisphosphonate treatment, an important therapeutic option for osteoporosis patients. Consequently, the development of novel formulations with improved tolerability is warranted. In this multicenter prospective, observational, postauthorization safety study conducted in Italy and Spain, postmenopausal women (PMW) with osteoporosis (naïve to bisphosphonates) were treated weekly with a buffered soluble alendronate 70 mg effervescent (ALN-EFF) tablet (Binosto®) and followed for 12 ± 3 months. Information was collected on adverse events (AEs), medication errors, persistence, and compliance using the Morisky-Green questi…
Management of hand osteoarthritis: from an US evidence-based medicine guideline to a European patient-centric approach.
2022
© Crown 2022. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the per…
Recolonization after habitat restoration leads to decreased genetic variation in populations of a terrestrial orchid.
2012
Colonization is crucial to habitat restoration projects that rely on the spontaneous regeneration of the original vegetation. However, as a previously declining plant species spreads again, the likelihood of founder effects increases through recurrent population founding and associated serial bottlenecks. We related Amplified Fragment Length Polymorphism markers genetic variation and fitness to colonization history for all extant populations of the outcrossing terrestrial orchid Dactylorhiza incarnata in an isolated coastal dune complex. Around 1970, D. incarnata suffered a severe bottleneck yet ultimately persisted and gradually spread throughout the spatially segregated dune slacks, aided…
Impact of Safety-Related Dose Reductions or Discontinuations on Sustained Virologic Response in HCV-Infected Patients: Results from the GUARD-C Cohor…
2015
Background: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or discontinuations (sr-RD) and their impact on sustained virologic response (SVR) in patients receiving peginterferon alfa/ribavirin in routine practice. Methods: A total of 3181 HCV-mono-infected treatment-naive patients were assigned to 24 or 48 weeks of peginterferon alfa/ribavirin by their physician. Patients were categorized by time-to-first sr-RD (Week 4/12). Detailed analyses of the i…
Geomorphologic Risk Modelling of the Sibiu Depression Using Geospatial Surface Analyses
2011
Extreme events in general, and the geomorphologic ones in particular, are highly topical problems. There were addresses by many researchers in the field of geology and physical geography (more specific by the climatologists and geomorphologists), but also by biologists, chemists, ecologists, etc. These are studied through the analysis of some types of processes and production mechanisms, and secondly by the effects they create on other environmental subsystems.