Search results for "evidence."
showing 10 items of 1017 documents
PARETO OR LOG-NORMAL? BEST FIT AND TRUNCATION IN THE DISTRIBUTION OF ALL CITIES*
2015
In the literature, the distribution of city size is a controversial issue with two common contenders: the Pareto and the log-normal. While the first is most accredited when the distribution is truncated above a certain threshold, the latter is usually considered a better representation for the untruncated distribution of all cities. In this paper, we reassess the empirical evidence on the best-fitting distribution in relation to the truncation point issue. Specifically, we provide a comparison among four recently proposed approaches and alternative definitions of U.S. cities. Our results highlight the importance to look at issue of the best-fitting distribution together with the truncation …
Ethics and economics, friends or foes? An educational debate
2004
This paper reviews an ongoing debate about moral standards for vocational education in German speaking countries. At the centre of the controversy is the question of universalistic versus domain‐specific moral orientations, namely the question of whether business people ought to develop different moral points of view in different situations (such as ‘private’ versus ‘professional’). Of pivotal importance in this context is also a prominent ethical approach (by Karl Homann, a philosopher in the tradition of liberal economists) which serves as a foundation for those who advocate domain specificity and which is strongly criticized by their counterparts. This approach is also presented, since t…
Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology.
2013
The aims of severe perioperative bleeding management are three-fold. First, preoperative identification by anamesis and laboratory testing of those patients for whom the perioperative bleeding risk may be increased. Second, implementation of strategies for correcting preoperative anaemia and stabilisation of the macro- and microcirculations in order to optimise the patient's tolerance to bleeding. Third, targeted procoagulant interventions to reduce the amount of bleeding, morbidity, mortality and costs. The purpose of these guidelines is to provide an overview of current knowledge on the subject with an assessment of the quality of the evidence in order to allow anaesthetists throughout Eu…
Methodological aspects of clinical trials in tinnitus: a proposal for an international standard
2012
Abstract: Chronic tinnitus is a common condition with a high burden of disease. While many different treatments are used in clinical practice, the evidence for the efficacy of these treatments is low and the variance of treatment response between individuals is high. This is most likely due to the great heterogeneity of tinnitus with respect to clinical features as well as underlying pathophysiological mechanisms. There is a clear need to find effective treatment options in tinnitus, however, clinical trials differ substantially with respect to methodological quality and design. Consequently, the conclusions that can be derived from these studies are limited and jeopardize comparison betwee…
Research in disaster settings: a systematic qualitative review of ethical guidelines
2016
Background Conducting research during or in the aftermath of disasters poses many specific practical and ethical challenges. This is particularly the case with research involving human subjects. The extraordinary circumstances of research conducted in disaster settings require appropriate regulations to ensure the protection of human participants. The goal of this study is to systematically and qualitatively review the existing ethical guidelines for disaster research by using the constant comparative method (CCM). Methods We performed a systematic qualitative review of disaster research ethics guidelines to collect and compare existing regulations. Guidelines were identified by a three-tie…
Cognitive processes related to problematic pornography use (PPU): A systematic review of experimental studies
2021
Highlights • Some people experience symptoms derived from pornography viewing. • Cognitive processes may be related to the development of Problematic Pornography Use (PPU). • We performed a systematic review of 21 studies exploring cognitive processes related to PPU. • We identified 4 cognitive processes relevant for the development and maintenance of PPU.
Clinical Nurses Research Priorities in Hospital Settings: A Delphi Survey
2021
This study aimed to identify the research priorities of clinical nurses to develop a research program at a health care services system that includes three hospitals. A Delphi survey was emailed to all clinical nurses in two rounds. The Delphi method was used to collect data from the nurses in regards to their priority research themes, and the data were analyzed using descriptive and comparative statistics. A total of 933 clinical nurses returned the first round of the Delphi survey and 543 nurses answered the second round. Clinical nurses identified 89 potential research themes. Patient safety and ethical challenges were the two highest ranked research priorities. The 40 highest ranked pri…
Positioning of the cross-stitch on the modified Kessler core tendon suture
2018
[EN] Cryopreserved human tendons were sutured with different variations of a modified Kessler-type grasping suture in a series of different designs in order to assess the influence of the distance between the cross-stitch on the core suture (5 and 10 mm from the cut tendon edge) on the peripheral suture. An original mathematical model was employed to explain the mechanical behavior (strength, deformation, and distribution of load) of the different suture designs. The effect of the peripheral epitendinous suture, combined with the distance of the core suture, was evaluated. The variation of core suture distance had no relevant consequences on the overall resilience of the design. However, in…
Vulnerability Black Markets: Empirical Evidence and Scenario Simulation
2009
This paper discusses the manifest characteristics of online Vulnerability Black Markets (VBM), insider actors, interactions and mechanisms, obtained from masked observation. Because VBM transactions are hidden from general view, we trace their precursors as secondary evidence of their development and activity. More general attributes of VBMs and the exploits they discuss are identified. Finally, we introduce a simulation model that captures how vulnerability discoveries may be placed in a dual legal-black market context. We perform simulations and find that if legal markets expose vulnerabilities that go unresolved, the security and quality of software may suffer more than in the absence of…
Predictores y efectos de la repetición de curso
2018
About a third of Spanish students will have repeated at least one school year by the time they reach 16. It is claimed that alternative policies top grade repetition should seek to provide individualised treatment and ensure early intervention. In Spain, while there is empirical evidence in support of the benefits of the former, there is little for the latter. Here, we fill this gap by combining data from two international assessments. We identify the profile of students who a) are at greatest risk of grade retention and b) are most negatively affected by the policy. Our results confirm the importance of early intervention and the need to rethink grade repetition as a one-size-fits-all poli…