Search results for "exam"
showing 10 items of 1241 documents
Tranexamic acid in cardiac surgery: Are low doses enough?
2020
OBJECTIVES Tranexamic acid is used to prevent hyperfibrinolysis and reduce postoperative bleeding and blood transfusions in on-pump cardiac surgery. We evaluate the efficacy of low or high dose tranexamic acid in a prospective cohort study conducted in Valencia. MATERIALS AND METHODS A total of 427 patients were recruited between January 2019 and January 2020, 207 in the Hospital General Universitario (low dose [LD]) and 220 in the Hospital Universitario y Politecnico La Fe (high dose [HD] and intermediate dose [ID]). We recorded the presence of hyperfibrinolysis on rotational thromboelastometry, intra- and postoperative administration of blood products, chest tube output within the first 1…
Analysis of involvement of the 3?-untranslated regions in regulating mRNA stability for vitellogenin, cyanoprotein ?, and cyanoprotein ? from the bea…
2002
The degradation of the 3'-untranslated regions (UTRs) of vitellogenin, cyanoprotein alpha, and cyanoprotein beta from the bean bug, Riptortus clavatus, was analyzed in vitro. The degradation pattern was similar for all three RNAs, with a high degradation rate in non-diapausing adult insects and no degradation in the fifth instar nymphs and in diapausing adults, and was not correlated with the expression levels of these three proteins. Proteins binding to the 3'-UTRs were detected in polysomal and cytosolic extracts. These factors, however, were present in all developmental stages. The abundance of the polysomal factor showed little variation, but the cytosolic factor was enriched in adult i…
Informatīvo materiālu ietekme uz pacientu sagatavotību urodinamikas izmeklēšanas metodei
2017
Pētījuma nosaukums “Informatīvo materiālu ietekme uz pacientu sagatavotību urodinamikas izmeklēšanas metodei”. Latvijā no urīna nesaturēšanas jeb patvaļīgas urīna izdalīšanās cieš apmēram 150 000 cilvēku. Statistiskas dati rāda, ka Latvijā urīna nesaturēšana ir sastopama katrai ceturtajai sievietei vecumā virs 35 gadiem (1). Pētījumi liecina, ka Latvijā aptuveni pusei no visiem pacientiem ir tā dēvētā slodzes inkontinence, 43% pacientu nesaturēšana ir jaukta tipa, kamēr 7% urīna nesaturēšanu izraisa pāraktīvs urīnpūslis (pastāvīgi kairināts urīnpūslis, kas var izraisīt pēkšņu un nepārvaramu urīnpūšļa iztukšošanos), to apstiprina īpaša diagnostika – urodinamiskie izmeklējumi (1). Urīna nesat…
Observer-Based Stabilization of Stochastic Systems with Limited Communication
2012
Published version of an article in the journal: Mathematical Problems in Engineering. Also available from Hindawi: http://dx.doi.org/10.1155/2012/781542 Open Access This paper studies the problem of observer-based stabilization of stochastic nonlinear systems with limited communication. A communication channel exists between the output of the plant and the input of the dynamic controller, which is considered network-induced delays, data packet dropouts, and measurement quantization. A new stability criterion is derived for the stochastic nonlinear system by using the Lyapunov functional approach. Based on this, the design procedure of observer-based controller is presented,which ensures asy…
Dexamethasone Inhibits the Pro-Angiogenic Potential of Primary Human Myoblasts
2021
Tissue regeneration depends on the complex processes of angiogenesis, inflammation and wound healing. Regarding muscle tissue, glucocorticoids (GCs) inhibit pro-inflammatory signalling and angiogenesis and lead to muscle atrophy. Our hypothesis is that the synthetic GC dexamethasone (dex) impairs angiogenesis leading to muscle atrophy or inhibited muscle regeneration. Therefore, this study aims to elucidate the effect of dexamethasone on HUVECs under different conditions in mono- and co-culture with myoblasts to evaluate growth behavior and dex impact with regard to muscle atrophy and muscle regeneration. Viability assays, qPCR, immunofluorescence as well as ELISAs were performed on HUVECs,…
Intravitreal dexamethasone implant versus anti-vascular endothelial growth factor therapy combined with cataract surgery in patients with diabetic ma…
2021
Objective: to compare outcomes of cataract surgery combined with either anti-Vascular Endothelial Growth Factor (anti-VEGF) therapy or dexamethasone implant (DEX) in patients with diabetic macular oedema (DMO). Methods: Pubmed and Embase databases were searched for studies reporting outcomes of diabetic cataract surgery combined with either anti-VEGF or DEX, with a follow-up ≥3 months. The primary outcome was the mean change in central macular thickness (CMT). Mean change in best corrected visual acuity (BCVA) was considered as a secondary outcome. The mean difference between baseline and post-treatment values (MD) with 95%-Confidence Interval (95%CI) was calculated and meta-analyses were p…
Solitary Vestibular Schwannoma: Decision Making of Treatments
2012
Therapeutic strategies of vestibular schwannomas treatment are changed in the last years. The improvement of surgical equipments and skills allowed increasing the numbers of successful operations in the last 10 years. The results improved in terms of survival, quality of life, recurrences, facial nerve function, and hearing preservation. Also the age of operated patients, once a restriction, becomes progressively a relative limitation to surgical indication. However the progressive widening of MRI availability give to the Otoneurologist the possibility to follow-up the patients with a relative simple radiological examination, delaying the decision to treat surgically the neoplasm only in ca…
Treatment of Anderson-Fabry Disease
2020
Fabry disease is an X-linked disorder of glycosphingolipid metabolism that results in progressive accumulation of neutral glycosphingolipids, predominantly globotriaosylsphingosine (Gb3) in lysosomes, as well as other cellular compartments of several tissues, causing multi-organ manifestations (acroparesthesias, hypohidrosis, angiokeratomas, signs and symptoms of cardiac, renal, cerebrovascular involvement). Pathogenic mutations lead to a deficiency of the lysosomal enzyme alpha-galactosidase A (GLA). In the presence of high clinical suspicion, a careful physical examination and specific laboratory tests are required. Finally, the diagnosis of Fabry’s disease is confirmed by the demonstrat…
<title>The perception of isoluminant coloured stimuli of amblyopic eye and defocused eye</title>
2008
In routine eye examination the visual acuity usually is determined using standard charts with black letters on a white background, however contrast and colour are important characteristics of visual perception. The purpose of research was to study the perception of isoluminant coloured stimuli in the cases of true and simulated amlyopia. We estimated difference in visual acuity with isoluminant coloured stimuli comparing to that for high contrast black-white stimuli for true amblyopia and simulated amblyopia. Tests were generated on computer screen. Visual acuity was detected using different charts in two ways: standard achromatic stimuli (black symbols on a white background) and isoluminan…
The influence of micronutrients on oral and general health
2011
Abstract Objective The aim of the present clinical pilot study was to examine the influence of a combination of micronutrients on individuals with high stress experience. Methods 40 healthy students (28 female, 12 male) with a mean age of 27.1 ± 3.0 years, experiencing high examination stress, were chosen. After approval of the ethics commission, one group of students (n = 19) took a combination of micronutrients (Orthomol vital m/f) for three months, whereas other students (n = 21) served as control group. All participants underwent at the beginning and at the end of the trial a dental examination, a determination of 10 periodontal pathogens, a salivary and a blood analysis. In addition, t…