Search results for "excision"

showing 10 items of 266 documents

Characteristics, Management Techniques, and Outcomes of the Most Common Soft-Tissue Hand Tumors: A Literature Review and Our Experience

2017

INTRODUCTION Diagnosis of the hand's soft-tissue tumors is often difficult because of the different anatomic structures present in this region and yet clinicians must be able to distinguish typical benign entities from life-threatening or limb-threatening malignant diseases. MATERIALS AND METHODS At the Department of Plastic and Reconstructive Surgery at the University of Palermo, 629 patients with hand tumors were studied. Treatment was surgical for all of them; also radiotherapy and chemotherapy were necessary based on the histological diagnosis. CONCLUSIONS Our retrospective study with a literature review aims to present the most commonly observed soft-tissue hand lesions, analyzing thei…

MaleReconstructive surgerymedicine.medical_specialtySoft Tissue NeoplasmSkin Neoplasmssurgical excisionPrognosimedicine.medical_treatmentTreatment outcomeSoft Tissue Neoplasms030230 surgeryRisk Assessment03 medical and health sciences0302 clinical medicineInstrumental evaluationRetrospective StudieHistological diagnosismedicineHumansReconstructive Surgical ProcedureSkin NeoplasmSoft Tissue NeoplasmRetrospective Studieshand tumorbusiness.industryGeneral surgeryIncidenceSoft tissueDisease ManagementRetrospective cohort studyPlastic Surgery ProceduresPrognosisHandSurgeryRadiation therapyTreatment Outcomesoft-tissue lesionItaly030220 oncology & carcinogenesisSurgeryFemalebusinessHuman
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Trends and outcome of neoadjuvant treatment for rectal cancer: A retrospective analysis and critical assessment of a 10-year prospective national reg…

2021

Introduction: Preoperative treatment and adequate surgery increase local control in rectal cancer. However, modalities and indications for neoadjuvant treatment may be controversial. Aim of this study was to assess the trends of preoperative treatment and outcomes in patients with rectal cancer included in the Rectal Cancer Registry of the Spanish Associations of Surgeons. Method: This is a STROBE-compliant retrospective analysis of a prospective database. All patients operated on with curative intention included in the Rectal Cancer Registry were included. Analyses were performed to compare the use of neoadjuvant/adjuvant treatment in three timeframes: I)2006–2009; II)2010–2013; III)2014–2…

MaleSurvivalColorectal cancermedicine.medical_treatmentT stage030230 surgeryTNM0302 clinical medicineRegistriesStage (cooking)Rectal cancerAged 80 and overMargins of ExcisionGeneral MedicineMiddle AgedNeoadjuvant TherapySurvival Ratemedicine.anatomical_structureTreatment OutcomeOncology030220 oncology & carcinogenesisFemaleAdultmedicine.medical_specialtyNeoadjuvant treatmentPrognosiRectum03 medical and health sciencesYoung AdultmedicineAdjuvant therapyHumansChemotherapyAgedNeoplasm StagingRetrospective StudiesChemotherapyRadiotherapybusiness.industryRectal NeoplasmsCancerChemoradiotherapy Adjuvantmedicine.diseaseSurgeryRadiation therapySpainT-stageSurgerybusinessFollow-Up StudiesForecasting
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Head-Mounted Mixed-Reality Technology During Robotic-Assisted Transanal Total Mesorectal Excision

2019

INTRODUCTION Head-mounted mixed-reality technologies may enable advanced intraoperative visualization during visceral surgery. In this technical note, we describe an innovative use of real-time mixed reality during robotic-assisted transanal total mesorectal excision. TECHNIQUE Video signals from the robotic console and video endoscopic transanal approach were displayed on a virtual monitor using a head-up display. The surgeon, assistant, and a surgical trainee used this technique during abdominal and transanal robotic-assisted total mesorectal excision. We evaluated the feasibility and usability of this approach with the use of validated scales. RESULTS The technical feasibility of the rea…

MaleVisceral surgerymedicine.medical_specialtyRobotic assistedComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISIONTransanal approachAdenocarcinoma03 medical and health sciences0302 clinical medicineRobotic Surgical ProceduresHumansMedicineMesenteryMedical physicsAgedTransanal Endoscopic SurgeryProctectomyRectal Neoplasmsbusiness.industryVirtual RealityGastroenterologyTechnical noteUsabilityGeneral MedicineTotal mesorectal excisionMixed realityVisualization030220 oncology & carcinogenesis030211 gastroenterology & hepatologybusinessDiseases of the Colon & Rectum
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Completion Surgery After Concomitant Chemoradiation in Locally Advanced Cervical Cancer: A Comprehensive Analysis of Pattern of Postoperative Complic…

2014

Background: We provided a comprehensive analysis of rate, pattern, and severity of early and late postoperative complications in a very large, single-institution series of locally advanced cervical cancer (LACC) patients administered CT/RT plus radical surgery (RS). Methods: A total of 362 consecutive LACC (FIGO stage IB2-IVA) patients were submitted to RS after CT/RT at the Gynecologic Oncology Unit of the Catholic University (Rome/Campobasso). At 4 weeks after CT/RT, patients were evaluated for objective response and triaged to radical hysterectomy and pelvic ± aortic lymphadenectomy. Surgical morbidity was classified according to the Chassagne's grading system. Results: Most cases underw…

Malecervical cancermedicine.medical_treatmentUterine Cervical NeoplasmsPostoperative ComplicationsAntineoplastic Combined Chemotherapy Protocols80 and overlocally advanced cervical cancerAdjuvantSettore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIAAged 80 and overCervical cancerMedicine (all)Middle AgedPrognosisCombined Modality TherapyAdult; Aged; Aged; 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Squamous Cell; Chemotherapy; Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hysterectomy; Lymph Node Excision; Male; Middle Aged; Neoplasm Grading; Postoperative Complications; Prognosis; Radiotherapy; Adjuvant; Survival Rate; Uterine Cervical Neoplasms; Young AdultSurvival RateOncologyChemotherapy AdjuvantCarcinoma Squamous CellFemaleFluorouracilAdultmedicine.medical_specialtyGynecologic oncologyHysterectomyYoung AdultmedicineHumansChemotherapyRadical HysterectomyRadical surgeryconcomitant chemoradiationSurvival rateAgedHysterectomyRadiotherapybusiness.industryCarcinomamedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIASquamous CellConcomitantLymph Node ExcisionRadiotherapy AdjuvantSurgeryLymphadenectomyCisplatinNeoplasm GradingbusinessFollow-Up StudiesAnnals of Surgical Oncology
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Total mesorectal excision with intraoperative assessment of internal anal sphincter innervation provides new insights into neurogenic incontinence

2012

Background: The aim of this prospective study was to assess internal anal sphincter (IAS) innervation in patients undergoing total mesorectal excision (TME) by intraoperative neuromonitoring (IONM). Study Design: Fourteen patients underwent TME. IONM was carried out through pelvic splanchnic nerve stimulation under continuous electromyography of the IAS. Anorectal function was assessed with the digital rectal examination scoring system and a standardized questionnaire. Results: Nine of 11 patients who underwent low anterior resection had positive IONM results, with stimulation-induced increased IAS electromyographic amplitudes (median 0.23 V (interquartile range [IQR] 0.05, 0.56) vs median …

Malemedicine.medical_specialtyColorectal cancerAnal CanalElectromyographyAutonomic Nervous SystemInternal anal sphincterInterquartile rangeMonitoring IntraoperativeSurveys and QuestionnairesHumansMedicineFecal incontinenceProspective StudiesProspective cohort studyAgedAged 80 and overmedicine.diagnostic_testElectromyographyRectal Neoplasmsbusiness.industryRectumRectal examinationMiddle Agedmedicine.diseaseTotal mesorectal excisionSurgeryTreatment OutcomeFeasibility StudiesFemaleSurgerymedicine.symptombusinessFecal Incontinence
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Selective approach for upper rectal cancer treatment: total mesorectal excision and preoperative chemoradiation are seldom necessary.

2015

The implementation of preoperative chemoradiation combined with total mesorectal excision has reduced local recurrence rates in rectal cancer. However, the use of both types of treatment in upper rectal cancer is controversial.The purpose of this work was to assess oncological results after radical resection of upper rectal cancers compared with sigmoid, middle, and lower rectal cancers and to determine risk factors for local recurrence in upper rectal cancer.This was a retrospective analysis of prospectively collected data.This study was conducted in a tertiary care referral hospital in Valencia, Spain.Analysis included 1145 patients who underwent colorectal resection with primary curative…

Malemedicine.medical_specialtyColorectal cancerUnnecessary ProceduresPreoperative careDisease-Free SurvivalRisk FactorsPreoperative CareMedicineHumansSurvival rateAgedNeoplasm StagingRetrospective StudiesPreoperative chemoradiotherapybusiness.industryRectal NeoplasmsGastroenterologyFollow up studiesRetrospective cohort studyGeneral MedicineChemoradiotherapy Adjuvantmedicine.diseasePrognosisTotal mesorectal excisionMagnetic Resonance ImagingSurvival RateSigmoid NeoplasmsTreatment OutcomeFemaleRadiologyNeoplasm Recurrence LocalbusinessChemoradiotherapyFollow-Up StudiesDiseases of the colon and rectum
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Does conversion during minimally invasive rectal surgery for cancer have an impact on short-term and oncologic outcomes? Results of a retrospective c…

2021

International audience; Background: Although minimally invasive rectal surgery (MIRS) for cancer provides better recovery for similar oncologic outcomes over open approach, conversion is still required in 10% and its impact on short-term and long-term outcomes remains unclear. The aim of our study was to evaluate the impact of conversion on postoperative and oncologic outcomes in patients undergoing MIRS for cancer. Methods: From June 2011 to March 2020, we reviewed 257 minimally invasive rectal resections for cancer recorded in a prospectively maintained database, with 192 robotic and 65 laparoscopic approaches. Patients who required conversion to open (Conversion group) were compared to t…

Malemedicine.medical_specialtyColorectal cancermedicine.medical_treatmentPostoperative ComplicationsRobotic Surgical ProceduresMinimally invasive surgeryLaparotomymedicineHumansRobotic surgeryRectal cancerLaparoscopyRetrospective Studiesmedicine.diagnostic_testbusiness.industryRectal NeoplasmsCancerRetrospective cohort studyConversionRobotic surgerymedicine.diseaseTotal mesorectal excisionSurgeryTreatment OutcomeSurgeryLaparoscopybusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyAbdominal surgerySurgical endoscopy
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Robot-assisted minimally invasive esophagectomy (RAMIE) compared to conventional minimally invasive esophagectomy (MIE) for esophageal cancer: a prop…

2020

SUMMARY Robot-assisted minimally invasive esophagectomy (RAMIE) is increasingly being applied as treatment for esophageal cancer. In this study, the results of 50 RAMIE procedures were compared with 50 conventional minimally invasive esophagectomy (MIE) operations, which had been the standard treatment for esophageal cancer prior to the robotic era. Between April 2016 and March 2018, data of 100 consecutive patients with esophageal carcinoma undergoing modified Ivor Lewis esophagectomy were prospectively collected. All operations were performed by the same surgeon using an identical intrathoracic anastomotic reconstruction technique with the same perioperative management and pain control re…

Malemedicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatmentRamielaw.invention03 medical and health sciences0302 clinical medicinePostoperative ComplicationsRobotic Surgical ProcedureslawJournal ArticlemedicineHumansMinimally Invasive Surgical Proceduresesophageal cancerProspective StudiesIvor LewisPropensity ScoreAgedRAMIEMIEbusiness.industryStandard treatmentIncidenceGastroenterologyGeneral MedicineEsophageal cancerMiddle Agedmedicine.diseaseIntensive care unitSurgeryEsophagectomyRegimenTreatment OutcomeEsophagectomy030220 oncology & carcinogenesisPropensity score matchingminimally invasiveLymph Node Excision030211 gastroenterology & hepatologyLymphadenectomyFemalebusinessDiseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
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The SIC-GIRCG 2013 Consensus Conference on Gastric Cancer.

2014

Abstract The topic chosen by the Board of the Italian Society of Surgery for the 2013 annual Consensus Conference was gastric cancer. With this purpose, under the direction of 2 chairmen, 36 experts nominated by the Regional Societies of Surgery and by the Italian Research Group for Gastric Cancer (GIRCG) participated in an experts consensus exercise, preceded by a questionnaire and mainly held by telematic vote, in accordance with the rules of the Delphi method. The results of this Consensus Conference, presented to the 115th National Congress of the Italian Society of Surgery, and approved in plenary session, are reported in the present paper.

Malemedicine.medical_specialtyGastric cancer Surgery Chemotherapy Staging Endoscopy LaparoscopyStagingDelphi TechniqueMEDLINEDelphi methodchemotherapyEndosonographyDelphi Technique; Endosonography; Female; Humans; Italy; Lymph Node Excision; Male; Neoplasm Staging; Societies Medical; Stomach NeoplasmsStomach NeoplasmStomach NeoplasmsMedicalmedicineHumanslapaoscopyguidelinesgastric cancer; chemotherapy; staging endoscopy; lapaoscopySocieties MedicalNeoplasm StagingSettore MED/06 - ONCOLOGIA MEDICAtreatmentbusiness.industryConsensus conferenceCancerEndoscopymedicine.diseasePlenary sessionSurgerySettore MED/18 - Chirurgia GeneraleGastric CancerItalyLymph Node ExcisionNeoplasm stagingLaparoscopySurgeryFemaleguidelines; Gastric Cancer; treatmentbusinessSocietiesstaging endoscopyHuman
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Late-onset myasthenia gravis - CTLA4(low) genotype association and low-for-age thymic output of naïve T cells.

2014

Abstract Late-onset myasthenia gravis (LOMG) has become the largest MG subgroup, but the underlying pathogenetic mechanisms remain mysterious. Among the few etiological clues are the almost unique serologic parallels between LOMG and thymoma-associated MG (TAMG), notably autoantibodies against acetylcholine receptors, titin, ryanodine receptor, type I interferons or IL-12. This is why we checked LOMG patients for two further peculiar features of TAMG – its associations with the CTLA4 high/gain-of-function  +49A/A genotype and with increased thymic export of naive T cells into the blood, possibly after defective negative selection in AIRE-deficient thymomas. We analyzed genomic DNA from 116 …

Malemedicine.medical_specialtyGenotypeThymomaT-LymphocytesImmunologyDNA Mutational AnalysisRecent Thymic EmigrantLate onsetCell CountThymus GlandBiologyPeripheral blood mononuclear cellWhite PeopleGene FrequencyInternal medicineGenotypeMyasthenia GravismedicineImmune ToleranceImmunology and AllergyHumansCTLA-4 AntigenGenetic Predisposition to DiseaseGenetic Association StudiesAgedPeripheral tolerance inductionAged 80 and overPolymorphism GeneticThymocytesT-cell receptor excision circlesAutoantibodyCell DifferentiationThymus NeoplasmsMiddle Agedmedicine.diseaseMyasthenia gravisEndocrinologyImmunologyFemaleJournal of autoimmunity
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