Search results for "exhaust"

showing 8 items of 138 documents

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

2015

International audience; Whereas preclinical investigations and clinical studies have established that CD8+ T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8+ T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8+ T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8+ T cell immunity, leading to the emergence of dysfunctional CD8+ T cells. The existence of different types of CD8+ T…

senescenceT cellOncology and CarcinogenesisImmunology[SDV.CAN]Life Sciences [q-bio]/CancerBiologyCD8+ T cellsIFN gammaanergy03 medical and health sciencesstemness0302 clinical medicineImmune system[SDV.CAN] Life Sciences [q-bio]/Cancerexhaustionmedicine2.1 Biological and endogenous factorsImmunology and AllergyCytotoxic T cellAetiologyPoint of ViewCancer030304 developmental biologyCD8+ T cells; IFNγ; anergy; anticancer immunity; cytotoxicity; effector; exhaustion; senescence; stemness0303 health sciencesTumor microenvironmentCD8(+) T cellsCancermedicine.diseasePhenotype3. Good healthanticancer immunitymedicine.anatomical_structureeffectorOncologyImmunologycytotoxicityCytokine secretionCD8030215 immunologyIFNγ
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Emotional user experience and feeling of control

2015

Current research on emotional user experience lacks a clear exposition on the relationship between feeling of control and the emotion response. The appraisal theory of emotion posits that perceived control over an event is an important factor in determining the emotional response to the event. It is therefore hypothesised, that the relationship between emotional experiences and interaction events is mediated by feeling of control. In an experiment (N = 38), participants used a joystick to control game objects, and gave self-reports of their emotional states and feeling of control. Pathway analyses predicting the factors of emotional experience with event logs reveal that feeling of control …

ta113business.industrymedia_common.quotation_subjectemotionEmotion workAppraisal theoryfeeling of controlPAD emotional state modelFeelingUser experience designuser experienceEmotional expressionPsychologybusinessEmotional exhaustionSocial psychologyCompetence (human resources)ta515media_common
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The effect of perceived school climate and teacher efficacy in behavior management on job satisfaction and burnout: A longitudinal study

2016

Abstract This study investigated how perceived school climate affects teachers' job satisfaction and burnout and how self-efficacy and collective efficacy in behavior management mediate the effect of perceived school climate on job satisfaction and burnout. The questions were answered using longitudinal questionnaire data collected from 642 Finnish lower secondary school teachers. A structural equation model revealed that school climate had a positive effect, partly mediated by self-efficacy, on job satisfaction. Collective efficacy in student discipline did not explain either job satisfaction or burnout. Self-efficacy in managing behavior had a positive effect on job satisfaction and a neg…

teachersburnouteducation05 social sciences050301 educationbehavior managementContext (language use)Job attitudeBurnoutteacher efficacyEducationCollective efficacyJob performanceta5160501 psychology and cognitive sciencesBehavior managementJob satisfactionEmotional exhaustionPsychologyschool climate0503 educationSocial psychologypsychological phenomena and processesjob satisfaction050104 developmental & child psychologyTeaching and Teacher Education
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New is not always costly: evidence from online processing of topic and contrast in Japanese.

2013

Two visual ERP experiments were conducted to investigate topic and contrast assigned by various cues such as discourse context, sentential position and marker during referential processing in Japanese. Experiment 1 showed that there was no N400-difference for new vs. given noun phrases (NPs) when the new NP was expected (contrastively focused) based on its preceding context and sentential position. Experiment 2 further revealed that the N400 for new NPs can be modulated by the NP’s contrastive meaning (exhausitivity) induced from the marker. Both experiments also showed that new NPs engendered an increased Late Positivity. The reduced N400 for new vs. given supports an expectation-based lin…

topicComputer sciencelcsh:BF1-990referential processingContext (language use)updatingRepresentation (arts)computer.software_genrePsychologyN400Original Research ArticleLate PositivityGeneral Psychologybusiness.industryOnline processingexhaustivityContrast (statistics)contrastN400Noun phraselcsh:Psychologysentential positionJapaneseArtificial intelligencebusinesscomputerERPDiscourse markerNatural language processingexpectationMeaning (linguistics)Frontiers in psychology
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Staying connected and feeling less exhausted : The autonomy benefits of after‐hour connectivity

2023

This study investigates the longitudinal relationship between after-hour connectivity, autonomy and exhaustion. In doing so, we seek to illuminate the role of individuals' connectivity to work in relation to their autonomy and well-being. We juxtapose different effective directions of the relationship between connectivity and autonomy to shed light on whether and how connectivity and autonomy are related to employees' well-being. This is important because research has both often problematized after-hour connectivity and suggested that connectivity is an inherent feature of contemporary workplaces that may benefit employees. In this study, we hypothesize that after-hour connectivity increase…

työaikaitsemäärääminentyöhyvinvointiexhaustionhyvinvointiautonomiaautonomytyöelämäresources and demandsresurssituupumusafter-hour connectivity
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Assessment of Occupational Health and Job Satisfaction in Workers with Intellectual Disability: A Job Demands–Resources Perspective

2021

In the contexts where people with intellectual disability work, there are factors that determine their job satisfaction. The objective of this study was to test the adequacy of the central assumptions of the Job Demands–Resources (JD-R) theory in workers with intellectual disability employed in different work alternatives. Data from 362 workers in sheltered workshops and 192 workers in supported employment were utilized. The model was contrasted using a structural equation model and a multi-group analysis. The results supported the suitability of the model and confirmed that job demands and job resources evoke two relatively independent processes such as health impairment and motivational p…

work engagement030506 rehabilitationassessmentHealth Toxicology and MutagenesisApplied psychologylcsh:Medicinejob demands–resources theoryArticleJob SatisfactionStructural equation modelingOccupational safety and health03 medical and health sciencesIntellectual DisabilitySurveys and Questionnairesexhaustion0502 economics and businessIntellectual disabilitymedicinework-related factorsHumansOccupational HealthSupported employmentMotivationWork engagementlcsh:R05 social sciencesPublic Health Environmental and Occupational Healthmedicine.diseaseTest (assessment)Work (electrical)Job satisfactionintellectual disabilities0305 other medical sciencePsychology050203 business & managementInternational Journal of Environmental Research and Public Health
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Teachers’ occupational well-being in relation to teacher–student interactions at the lower secondary school level

2023

This study investigated the relation between teachers’ occupational well-being and the quality of teacher–student interactions in lower secondary schools in Finland. Teachers (N = 48) self-rated their occupational well-being in terms of engagement, stress, job demands, and emotional exhaustion. Teacher–student interactions in classrooms were video-recorded and coded with the Classroom Assessment Scoring System. The results of multivariate regression analyses showed that teachers who reported higher work-related stress were observed with a lower quality of emotional support, classroom organization, and instructional support when controlling for background factors. It is proposed that the obs…

work engagementburnoutemotional exhaustionteacher–student interactionstyöhyvinvointityön imuteacher occupational well-beinglukiolower secondary schoolopettajatopettaja-oppilassuhdeuupumusEducationScandinavian Journal of Educational Research
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Back to Basics: The Relative Importance of Transformational and Fair Leadership for Employee Work Engagement and Exhaustion

2016

This study contributes to the literature on the supervisors’ role in employee well-being by drawing on two separate lines of research: transformational leadership and organizational justice. The purpose of the study was to investigate the unique contributions of transformational and fair leadership (justice behaviours of supervisors) on work engagement and exhaustion among employees within the framework of the Job Demands-Resources model (Bakker and Demerouti, 2007). In determining the unique contributions, we additionally acknowledged the role of work characteristics. A questionnaire study was conducted among Finnish municipal employees in a variety of occupations (N = 333, 87% women). The…

work engagementtyön imuServant leadershipCross-cultural leadership050109 social psychologylcsh:Labor. Work. Working classShared leadershipinterpersonal justiceuupumusTransactional leadershipPolitical sciencetransformational leadershipexhaustion0502 economics and businessLeadership stylelcsh:Industrial psychology0501 psychology and cognitive sciencesta515organizational justicetransformational leadership organizational justice interpersonal justice work engagement exhaustion work characteristicslcsh:HD4801-8943Psykologia - Psychology05 social sciencesEthical leadershipSituational leadership theoryTransformational leadershipwork characteristicsPsychology (miscellaneous)Social psychology050203 business & managementlcsh:HF5548.7-5548.85Scandinavian Journal of Work and Organizational Psychology
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