Search results for "experimental study"
showing 10 items of 31 documents
Early high-dosage atorvastatin treatment improved serum immune-inflammatory markers and functional outcome in acute ischemic strokes classified as la…
2016
Statins have beneficial effects on cerebral circulation and brain parenchyma during ischemic stroke and reperfusion. The primary hypothesis of this randomized parallel trial was that treatment with 80 mg/day of atorvastatin administered early at admission after acute atherosclerotic ischemic stroke could reduce serum levels of markers of immune-inflammatory activation of the acute phase and that this immune-inflammatory modulation could have a possible effect on prognosis of ischemic stroke evaluated by some outcome indicators. We enrolled 42 patients with acute ischemic stroke classified as large arteries atherosclerosis stroke (LAAS) randomly assigned in a randomized parallel trial to the…
Short-term effects of Finnish sauna bathing on blood-based markers of cardiovascular function in non-naive sauna users
2018
Emerging evidence suggests that sauna bathing is associated with reduced risk of cardiovascular and all-cause mortality events. However, the biochemical pathways by which sauna bathing might confer its effects on cardiovascular function are not certain. We aimed to study the acute effects of Finnish sauna bathing on various blood-based cardiovascular biomarkers. The study included 102 non-naive sauna users (54% male) with mean age of 51.9 years, who had at least one cardiovascular risk factor. Participants underwent a 30-min single sauna session (mean temperature, 73 °C). Biochemical profiling was conducted before, immediately after sauna and 30-min post-sauna. Overall median N-terminal pro…
Optimization of opioid therapy for preventing incident pain associated with bone metastases
2004
Breakthrough pain is a transitory flare of Pain superimposed on an otherwise stable pain pattern in patients treated with opioids. One form of breakthrough pain is incident pain, which is due to movement and is commonly associated with bone metastases. The development of this pain is rapid and no medication, administered "as needed," has such a rapid onset that it parallels this temporal Pattern of Pain. This study used a construct based on the prevention of this event, and implemented a new experimental paradigm. Specifically, the study determined whether increasing the opioid doses above those sufficient to control pain at rest would. reduce the occurrence of these pains. Twenty-five cons…
Sauna exposure leads to improved arterial compliance: Findings from a non-randomised experimental study.
2017
Background Heat therapy has been suggested to improve cardiovascular function. However, the effects of hot sauna exposure on arterial compliance and the dynamics of blood flow and pressure have not been well documented. Thus, we investigated the short-term effects of sauna bathing on arterial stiffness and haemodynamics. Design The design was an experimental non-randomised study. Methods There were 102 asymptomatic participants (mean age, 51.9 years) who had at least one cardiovascular risk factor. Participants were exposed to a single sauna session (duration: 30 min; temperature: 73℃; humidity: 10–20%). Pulse wave velocity, augmentation index, heart rate, blood pressure, mean arterial pres…
Effect of segmental muscle vibration on upper extremity functional ability poststroke
2019
Abstract Background: Upper extremity functional impairments are common consequences of stroke. Therefore, continuous investigation of effective interventions for upper extremity functions after stroke is a necessity. Segmental muscle vibration (SMV) is one of the interventions that incorporate sensory stimulation to improve motor cortical excitability. The aim of this study was to investigate the influence of 5-minute SMV application along with supervised physical therapy (SPT) on improving activities of daily living and motor recovery on the hemiparetic upper extremity in patients with stroke. Methods: A sample of 37 patients poststroke (29 males) was randomly allocated to either SPT contr…
Changes in physical activity and sedentary time in the Finnish Schools on the Move program: a quasi-experimental study
2017
The aim of the Finnish Schools on the Move program is to create a more active and pleasant school day through physical activity (PA). In this quasi-experimental design, we compared changes in moderate-to-vigorous-intensity physical activity (MVPA) and sedentary time (ST) during the school day and outside school hours for Grades 1–9 over two academic years in four program schools and two reference schools. Altogether 319 girls and boys aged 7–15 participated in the study between 2010 and 2012. MVPA and ST were measured four times over the 1.5-year follow-up period for seven consecutive days, using a hip-worn ActiGraph accelerometer. Linear growth curve modeling was used to examine the effect…
Experimental investigation on the effect of mortar grade on the compressive behaviour of FRCM confined masonry columns
2018
Abstract The use of Fiber Reinforced Cementitious Mortar (FRCM) systems for structural retrofitting of masonry structures has become increasingly popular in the last years, due to the capability of this technique in overcoming some of the drawbacks related to the adoption of resin-based composites. Recent studies investigated on the effect of FRCM wraps on the compressive behaviour of concrete members and demonstrated as the application of mortar-based composites allows increasing the strength and, above all, the ductility of the column. The main difference with FRP confined columns is related to the different post-peak behaviour, characterized by a softening branch. Differently, few studie…
Effect of corner over-reinforcing strips on the compressive behaviour of TRM confined masonry columns
2020
Several recent works studied the efficiency of inorganic matrix composites, namely Textile Reinforced Mortar (TRM) or Fabric Reinforced Cementitious Matrix, for enhancing the strength and shortening capacity of masonry columns subjected to axial load. Literature studies were addressed to study the great number of variables involved in the problem, such as the nature and the grade of mortar, the strength of the fabric, the number of reinforcing layers, the type, the arrangement and the strength of the masonry, and helped to draw the first technical guidelines for practitioners and designers. All the experimental works highlighted that the actual performance of TRM confinement in masonry memb…
Optical hysteresis in a semilinear photorefractive coherent oscillator
2007
International audience; High contrast optical bistability is found experimentally in the pump-ratio dependences of the output intensity of a semilinear photorefractive coherent oscillator with two counterpropagating pump waves. The data are in qualitative agreement with the results of calculation.
Effectiveness of therapy group in women with localized breast cancer
2018
Breast cancer causes high levels of anxiety and depression, deteriorating quality of life of patients. Several studies have found that group therapy reduces depression and anxiety also improves the quality of life. The aim of this study is to analyze group therapy effectiveness in emotional state and quality of life in women with breast cancer after finalized medical treatments.Participants in this study were 100 adult women diagnosed of breast cancer non-mestastasic and were divided into two types of intervention groups (Self-esteem-Social Skills and Cognitive-Behavioral Therapy). Evaluation instruments were questionnaire Functional Assessment of Breast-cancer Therapy (FACT-B) and Hospital…