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showing 10 items of 11436 documents

Tear Film Surface Quality in Modern Daily Disposable Contact Lens Wear

2021

Objectives As reported previously, tear film surface quality (TFSQ) should be considered in contact lens (CL) fitting. This study followed noninvasive keratograph tear film break-up time (NIKBUT) in CL wearers for 12 months to validate its clinical utility in predicting CL performance. Methods Fifty-five subjects (M/F=17/38) aged 26±4 years were prescribed silicone hydrogel or hydrogel CLs. The study included baseline measurements without CLs; 2 visits for CL fitting and control; follow-up after 3, 6, and 12 months of CL wear; and postwear visit without CLs. Ocular Surface Disease Index (OSDI), 8-Item Contact Lens Dry Eye Questionnaire (CLDEQ-8), first and mean NIKBUT (F/M-NIKBUT), fluoresc…

medicine.medical_specialtyCorneal stainingbusiness.industrySilicone hydrogelContact Lenses HydrophilicEyeContact lensOphthalmologyCLs upper limitsTearsOphthalmologyHumansTearsMedicineDry Eye SyndromesDaily disposableOcular Surface Disease IndexbusinessOcular surfaceVision OcularEye & Contact Lens: Science & Clinical Practice
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<p>A randomized multicenter study comparing seawater washes and carmellose artificial tears eyedrops in the treatment of dry eye syndrome</p…

2019

Purpose To investigate the safety and efficacy of sterile isotonic seawater washes vs standard treatment with carmellose artificial tears in dry eye syndrome (DES). Patients and methods This is a randomized multicenter prospective study with 12 weeks of follow-up. A group of patients with DES (N=60) were treated with seawater spray (Quinton®) five times daily, and another similar group (N=60) were treated with carmellose artificial tears eyedrops (Viscofresh® 0.5%) five times a day. The parameters studied and measured were as follows: Ocular Surface Disease Index questionnaire score, Schirmer I test (without anesthesia) score, tear osmolarity (TearLab®), tear breakup time, tear meniscus hei…

medicine.medical_specialtyCorneal stainingbusiness.industryStandard treatmentmedicine.medical_treatmenteye diseases03 medical and health sciencesOphthalmologyArtificial tears0302 clinical medicineMulticenter studyOphthalmology030221 ophthalmology & optometrymedicineTearsSeawaterOcular Surface Disease Indexsense organsbusinessProspective cohort study030217 neurology & neurosurgeryClinical Ophthalmology
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Evaluation of interface pressure and temperature management in five wheelchair seat cushions and their effects on user satisfaction

2020

Abstract Background Factors such as the manufacturing materials, shape or even the mechanical and thermal response of sitting Pressure Redistribution Support Surfaces (PRSS) can be potential contributors to pressure ulcers. However, few studies have compared a number of characteristics of the most frequently used devices. Objective To compare three potential contributors to pressure ulcers in five commercial PRSS: pressure redistribution, temperature and perceived comfort. Method: Study with a cross-over randomized design in healthy volunteer participants. Data was collected in a temperature and relative humidity controlled environment. To assess thermal response, the temperature (Flir-E60)…

medicine.medical_specialtyEnvironment controlledDermatologyDenture LinersSittingPathology and Forensic Medicine030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationWheelchairInterface pressurePressuremedicineHumansRelative humiditySpinal Cord InjuriesSitting PositionCross-Over Studies030504 nursingbusiness.industryUser satisfactionWheelchairsPatient SatisfactionThermographyCushionOpen cell0305 other medical sciencebusinessJournal of Tissue Viability
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SARS-CoV-2 outbreak in medical employees in a large urologic department: Spread, containment and outcome.

2021

Background The SARS-CoV-2 pandemic presents an unprecedented challenge to health care systems worldwide. Data on SARS-CoV-2 transmission in a hospital is rare and outbreaks among health care professionals are complex to control. Material and Methods Over the course of 6 consecutive weeks we recorded data on an exponential outbreak of SARS-CoV-2 within our department. We reconstructed the assumed route of the spread of infection, and the employees’ acute and late symptoms. Increasing preventive measures (mandatory face masks, intense training in hygiene, physical distancing whenever possible, and termination of visits from outside the hospital) were implemented. Results Within 6 weeks, 13 em…

medicine.medical_specialtyEpidemiologymedia_common.quotation_subjectSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Health PersonnelDisease Outbreaks03 medical and health sciences0302 clinical medicineHygienePandemicHealth careMajor ArticleMedicineHumans030212 general & internal medicinePandemicsmedia_common0303 health sciencesViral spreadPandemic030306 microbiologybusiness.industryTransmission (medicine)Medical settingSARS-CoV-2Health PolicyPublic Health Environmental and Occupational HealthOutbreakCOVID-19Face masksInfectious DiseasesEmergency medicinebusinessAmerican journal of infection control
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Online Professionalism-2018 Update of European Association of Urology (@Uroweb) Recommendations on the Appropriate Use of Social Media.

2018

Abstract Context Social media (SoMe) has transformed communication among health care professionals by enabling rapid and global information exchange. Yet, the novelty of SoMe and concerns about potential risks continue to be barriers to adoption. Objective To encourage appropriate professional use of SoMe by physicians in concordance with best practices and to update practical guidelines for effective and professional use of these communication technologies. Evidence aquisition The European Association of Urology (EAU; @Uroweb) brought together a committee of SoMe stakeholders in the urology field. PubMed and the grey literature were searched to identify SoMe position papers by other medica…

medicine.medical_specialtyFacebookAttitude of Health Personnel[SDV]Life Sciences [q-bio]Best practicemedia_common.quotation_subjectUrologistsUrologyTwitterWhatsApp030232 urology & nephrologyUrologyContext (language use)Guidelines[SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and NephrologyDigital media03 medical and health sciences0302 clinical medicineHonestyHealth caremedicineHumansSocial mediaCooperative BehaviorPhysician's RoleDigital mediamedia_commonCourtesybusiness.industryAttitude to ComputersYouTubeDigitalizationGrey literature3. Good healthScholarly CommunicationProfessionalism030220 oncology & carcinogenesisInstagramInterdisciplinary CommunicationbusinessProfessional MisconductSocial MediaConfidentialityEuropean urology
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Complications of Botulinum toxin A: An update review.

2021

Cosmetic surgery procedures have increased manifolds all over the world owing to the ever-increasing demand of people to look beautiful and young. Injectable treatments like botulinum toxin are becoming more popular owing to their rapid, well-defined, and lasting results for the reduction of facial fine lines, wrinkles, and facial rejuvenation. These emerging treatments are quite safe but can have certain adverse effects. In this article, we have highlighted the complications and side effects of botulinum toxin based on the anatomical location. The possible causes and precautions to prevent these complications are also discussed. The search of literature included peer-reviewed articles incl…

medicine.medical_specialtyFacial rejuvenationbusiness.industryMEDLINEDermatologyEnglish languageDermatologyBotulinum toxinBotulinum toxin aSkin AgingClinical trial030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineNeuromuscular Agents030220 oncology & carcinogenesisFacemedicineHumansRejuvenationBotulinum Toxins Type ASurgery PlasticAdverse effectbusinessmedicine.drugJournal of cosmetic dermatologyReferences
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Can Avatar Appearance Influence Physical Activity? User-Avatar Similarity and Proteus Effects on Cardiac Frequency and Step Counts

2020

This study combined user-avatar similarity and Proteus effect predictions to incentivize physical activity. 305 participants ran while wearing accelerometers and a heart rate monitor. They were randomly assigned to onscreen motion-capturing avatars displaying either participant or stranger faces dressed in sports or formal clothes. Participants assigned to avatars displaying their own face showed increased cardiac frequency compared with those exposed to avatars with a stranger's face. Relative to the remaining conditions, participants assigned to avatars with their own face also wearing sports clothes showed increased cardiac frequency but participants assigned to avatars with a stranger's…

medicine.medical_specialtyHealth (social science)Physical activity050801 communication & media studiesAudiologyUser-Computer Interface03 medical and health sciences0508 media and communicationsSimilarity (network science)medicineHumansExerciseComputingMethodologies_COMPUTERGRAPHICSAvatar030505 public healthbiologyCommunication05 social sciencesHeart rate monitorComputingMilieux_PERSONALCOMPUTINGProteus effectProteusbiology.organism_classificationProteus0305 other medical scienceCardiac frequencyPsychologyhuman activitiesHealth Communication
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Randomised clinical trials: a source of ethical dilemmas

2001

Clinical trials give rise to ethical dilemmas, especially in the acutely ill, but we take issue with two points raised in a recent comment on a specific acute myocardial infarction (AMI) trial. The commentators judged that the trial most likely could, and therefore should, have been terminated much earlier. By analysing the problem statistically we arrive at results that go against their intuitive judgment—they also see it as mandatory to update the patient Information sheet as trial results accrue and trends begin to emerge. In our view, interpreting subtle trends and borderline p-values must rest with data monitoring boards, not patients. Moreover, patients with AMI or in other medical em…

medicine.medical_specialtyHealth (social science)medicine.medical_treatmentAt the Coalface: Medical Ethics in PracticeTreatment outcomeMyocardial InfarctionAlternative medicineHospital mortalityResearch EthicsArts and Humanities (miscellaneous)Informed consentAngioplastymedicineHumansEthics MedicalThrombolytic TherapyHospital MortalityMyocardial infarctionIntensive care medicineRandomized Controlled Trials as TopicInformed Consentbusiness.industryPatient SelectionHealth PolicyAngioplastyCoronary Care Unitsmedicine.diseasehumanitiesClinical trialIssues ethics and legal aspectsTreatment OutcomeClinical researchEthics ClinicalData Interpretation StatisticalMedical emergencybusinessJournal of Medical Ethics
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Disposal Behavior of Used Masks during the COVID-19 Pandemic in the Moroccan Community: Potential Environmental Impact.

2021

The spread of coronavirus disease-2019 (COVID-19) levied on the Moroccan authorities to increase their mask production capacity, which reached up to 12 million facemask units produced per day. This increase in personal protective equipment (PPE) production and consumption is an efficient tool to address the spread of COVID-19. However, this results in more plastic and microplastic debris being added into the land and marine environments, which will harm the ecosystem, wildlife, and public health. Such a situation needs deep individual behavior observation and tracking, as well as an assessment of the potential environmental impact of this new type of waste. For this reason, we assessed the …

medicine.medical_specialtyHealth Toxicology and MutagenesisPopulation010501 environmental sciences01 natural sciencesFacemasksenvironmental impactArticleEnvironmental impact03 medical and health sciencesplastic pollution0302 clinical medicineCOVID‐19Environmental healthmedicineHumansEnvironmental impact assessment030212 general & internal medicineeducationPersonal protective equipmentPandemicsPersonal Protective EquipmentEcosystem0105 earth and related environmental sciencesConsumption (economics)education.field_of_studyBehaviorPublic healthbehaviorSARS-CoV-2Public healthpublic healthPublic Health Environmental and Occupational HealthRMasksCOVID-19MoroccoHarmGeographyGreenhouse gasPlastic pollutionCommunicable Disease ControlfacemasksMedicinePlastic pollutionPlasticsInternational journal of environmental research and public health
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Lysosomal trafficking in rat cardiac myocytes.

1990

By immunolabeling of cryosections, we have characterized in rat cardiac myocytes the cation-independent mannose-6-phosphate receptor (MPR), a lysosomal membrane glycoprotein, lgp120, and a lysosomal enzyme, MEP (homologous to cathepsin L). Most of the MPR label was located in large membrane-filled structures (MPR structures) in large clusters of mitochondria adjacent to but distinct from the Golgi complex. Lpg120 and MEP showed typical lysosomal localization throughout the cell, often associated with regions that appeared to contain autophagosome-like structures. In addition, MEP and lgp120 co-localized within MPR structures. MEP and MPR were localized inside the lumen of MPR structures. M…

medicine.medical_specialtyHistologyCathepsin LImmunoblottingFluorescent Antibody TechniqueReceptors Cell SurfaceMitochondrionMitochondria HeartReceptor IGF Type 2Cathepsin LImmunolabelingsymbols.namesakeAntigens CDLysosomal-Associated Membrane Protein 1Internal medicineLysosomeEndopeptidasesmedicineAnimalsFrozen SectionsMyocyteReceptorchemistry.chemical_classificationMembrane GlycoproteinsbiologyMyocardiumLysosome-Associated Membrane GlycoproteinsIntracellular MembranesGolgi apparatusCathepsinsRatsCell biologyCysteine EndopeptidasesMicroscopy ElectronEndocrinologymedicine.anatomical_structureAnimals NewbornLiverchemistrybiology.proteinsymbolsCattleAnatomyLysosomesGlycoproteinJournal of Histochemistry & Cytochemistry
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