Search results for "facilities"
showing 10 items of 304 documents
Colorectal Cancer in Elderly Patients: From Best Supportive Care to Cure
2013
Colorectal cancer is one of the major causes of cancer mortality in the elderly population (median age at diagnosis of 71 years) in Western Countries. Moreover patients with metastatic disease are often elderly with significant co- morbidities. Unfortunately, elderly patients are often untreated and under-represented in clinical trials, even if most clinical trials that have included this setting of population have shown similar survival rates and toxicities to younger patients. Age itself should not be considered for candidacy to chemotherapy but it should be taken in consideration the great heterogeneity of co-morbidities present in the elderly population. Therefore, the best treatment st…
Hospital and outpatient models for Hematopoietic Stem Cell Transplantation: A systematic review of comparative studies for health outcomes, experienc…
2021
The number of Hematopoietic Stem Cell Transplantations has risen in the past 20 years. The practice of outpatient Hematopoietic Stem Cell Transplantation programs is increasing in an attempt to improve the quality of patient care and reduce the demand for hospital admission. A systematic review of 29 comparative studies between in-hospital and outpatient treatment of Hematopoietic Stem Cell Transplantation, with no restriction by outpatient regime was conducted. This study aims to analyse the current evidence on the effects of the outpatient model on patient-centred outcomes, comparing both in-hospital and outpatient models for autologous and allogeneic HSCT using the Triple Aim framework: …
Child maltreatment by nursing staff and caregivers in German institutions: A population-representative analysis.
2019
Abstract Background Child maltreatment by caregivers seem to make a significant contribution to general maltreatment rates. Interestingly, research assessing prevalence rates of maltreatment mainly focuses on individual components either in relation to different types of maltreatment or in relation to different types of institutions. Objective The current study assesses prevalence rates for child maltreatment by caregivers in hospitals, rehabilitation centers, facilities for the disabled, schools, Kindergartens, and after-school care or residential care. Participants and setting: In a cross-sectional survey, a representative sample of the German population above the age of 14 (N = 2,516) wa…
Prevalence of burnout in a sample of Brazilian teachers
2011
Background and Objectives: Burnout is a psychological response to chronic work-related stress of an interpersonal and emotional nature. Brazilian law have already contemplated burnout syndrome as a mental and behavioural disorder related to work. The aim of this study was to identify the prevalence of burnout in a sample of Brazilian teachers. Methods: The sample was composed of 714 teachers from 8 schools in Porto Alegre and its metropolitan area (Brazil). The levels of burnout were evaluated by the Spanish Burnout Inventory, educational version (SBI-Ed). In addition, Psychosomatic disorders were estimated by the UNIPSICO subscale. Results: The percentage of participants who indicated high…
Smart Phone, Smart Science: How the Use of Smartphones Can Revolutionize Research in Cognitive Science
2011
WOS:000295936900019; International audience; Investigating human cognitive faculties such as language, attention, and memory most often relies on testing small and homogeneous groups of volunteers coming to research facilities where they are asked to participate in behavioral experiments. We show that this limitation and sampling bias can be overcome by using smartphone technology to collect data in cognitive science experiments from thousands of subjects from all over the world. This mass coordinated use of smartphones creates a novel and powerful scientific "instrument" that yields the data necessary to test universal theories of cognition. This increase in power represents a potential re…
Perfil del usuario de la fundación deportiva municipal de valencia y sus hábitos de práctica deportiva
2019
El objetivo de la presente investigación es analizar el uso de las instalaciones de la Fundación Deportiva Municipal de Valencia y determi- nar el perfil del usuario de las mismas. Para ello se recogen un total de 727 cuestionarios vía online formados por diferentes secciones extraídas a partir de la bibliografía existente. Los resultados muestran una alta satisfacción e intenciones futuras de los usuarios. Además, los usuarios muestran una ma- yor pasión armoniosa por el deporte en comparación con la pasión obsesiva. La mayor parte de la práctica deportiva se concentra entre semana y a partir de las 19:00h. Los usuarios de las instalaciones en su mayoría tienen trabajo y estudios universit…
RETROFITTING DETENTION BUILDINGS OF HISTORICAL-CULTURAL INTEREST. A CASE STUDY IN ITALY
2021
Penitentiary buildings in Italy include many buildings of undoubted historical and architectural importance. These have been, or will soon be, subject to structural changes necessary to adapt their spaces to the current regulations of prisons. The idea of punishment itself has changed over the centuries, so it is a physiological necessity to adapt existing buildings accordingly. When, however, such buildings date back centuries, they should not be considered a mere container but a historical testimony rich in meaning for the entire nation. The characteristics of the materials, distribution, and what these buildings have represented for the city should be the object of study and protection, …
Prevalence and risk factors of actinic keratosis in patients attending Italian dermatology clinics
2017
Background: Actinic keratosis (AK) is a common keratinocyte intraepidermal neoplasia. Objective: To assess AK prevalence and potential risk factors in patients attending Italian general dermatology clinics. Materials & methods: This retrospective study was conducted on clinical data from consecutive white outpatients aged ≥30 years, attending 24 general dermatology clinics between December 2014 and February 2015. AK prevalence (entire population) and multivariate risk factor analysis (patients with current/previous AK and complete data) are presented. Results: AK prevalence in 7,284 patients was 27.4% (95% CI: 26.4-28.4%); 34.3% in men and 20.0% in women (p<0.001). Independent AK ris…
Computational Approaches: Drug Discovery and Design in Medicinal Chemistry and Bioinformatics
2021
To date, computational approaches have been recognized as a key component in drug design and discovery workflows. Developed to help researchers save time and reduce costs, several computational tools have been developed and implemented in the last twenty years. At present, they are routinely used to identify a therapeutic target, understand ligand–protein and protein–protein interactions, and identify orthosteric and allosteric binding sites, but their primary use remains the identification of hits through ligand-based and structure-based virtual screening and the optimization of lead compounds, followed by the estimation of the binding free energy. The repurposing of an old drug for the tr…
Pheromone-induced odour learning in newborn rabbits: action, development and adaptive function
2012
Communication orale; International audience