Search results for "fertility"
showing 10 items of 629 documents
Fertility outcome after radical vaginal trachelectomy: a prospective study of 212 patients.
2011
ObjectiveFor treatment in patients with early-stage cervical cancer, radical vaginal trachelectomy (RVT) as a fertility-preserving surgery can be put on a par with radical hysterectomy as to oncologic safety. Our aim was to investigate the fertility concerns and outcome.MethodsProspective collection of fertility data of patients treated with RVT. The data were collected on personal communication, by telephone, or e-mail correspondence. Descriptive statistical analysis was performed.ResultsBetween March 2005 and April 2010, 212 patients were followed up after RVT. Only 76 patients (35.9%) were seeking parenthood currently. Sixty pregnancies occurred in 50 women. Five patients (8.3%) had firs…
Evaluation of Borderline Ovarian Tumor Recurrence Rate after Surgery with or without Fertility-Sparing Approach: Results of a Retrospective Analysis
2023
Borderline ovarian tumors (BOTs) comprise 15-20% of primary ovarian neoplasms and represent an independent disease entity among epithelial ovarian cancers. The present study (Clinical Trial ID: NCT05791838) aimed to report a retrospective analysis of the management and outcomes of 86 consecutive BOTs patients, 54 of which were at a reproductive age. All patients with BOTs undergoing surgical treatment from January 2010 to December 2017 were included. Data were retrospectively reviewed. High levels of Ca-125 were observed in 25.6% of the FIGO stage I patients and 58.3% of the advanced disease patients. Fertility-sparing surgery and comprehensive surgical staging were performed in 36.7% and 4…
Uterine sarcomas: A critical review of the literature
2023
This review aims to provide a comprehensive description of surgical approaches for the management of uterine sarcomas. Uterine sarcomas are rare uterine neoplasms. Frequently, diagnosis is made after hysterectomy or myomectomy scheduled for presumed benign leiomyomas. The gold standard for surgical treatment of uterine sarcomas is hysterectomy with bilateral salpingo-oophorectomy. It is possible to adopt a fertility-sparing approach for those patients who wish to maintain their fertility. The role of pelvic lymphadenectomy is controversial; in fact, removal of lymph nodes is only recommended in the case of radiological suspicion of nodal involvement. Use of a morcellator is associated with …
Reproductive and Obstetric Outcomes after Fertility-Sparing Treatments for Cervical Cancer: Current Approach and Future Directions
2023
Cervical cancer is one of the leading causes of cancer-related death in women of reproductive age. The established fertility-sparing approaches for the management of early-stage cervical cancer for women who plan pregnancy are associated with a decline in fecundity and an increased risk of pregnancy complications. This article aims to offer an overview of fertility-sparing approaches and the management of potential subfertility and pregnancy complications after these treatments. An extensive search for the available data about infertility and cervical cancer, fertility-sparing techniques in patients with cervical cancer, fertility treatment, obstetrical complications, and pregnancy outcomes…
Editorial: Minimally invasive surgery as a mean of improving fertility: What do we know so far?
2023
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Sensitivity of soil processes in northern forest soils: are management practices a threat?
2000
Abstract There is evidence that forest management practices influence soil-decomposer communities. It is also established that changes in the trophic structure and composition of these communities can induce changes in soil-nutrient dynamics, thereby affecting plant growth. Whether forest productivity is affected by management-induced changes in, e.g. soil faunal structure, is, however, yet to be shown. The aim of this study was (1) to determine the resolution of the ecological hierarchy (e.g. species, functional groups, trophic levels) at which a change in soil fauna would alter biotically-controlled processes in soils, and (2) to examine the sensitivity of soil fauna of the boreal forest …
Past and Contemporary Changes in Forest Cover and Forest Continuity in Relation to Soils (Southern Latvia)
2014
A set of medium-scale historical maps was used to reconstruct changes in spatial patterns of forest area during the last 220 years in an agricultural matrix of northeastern Europe (Zemgale region, Latvia). Changes in total forest area by soils were determined, as well as the time period of continuous forest cover. Proportion of protected area for each soil trophic group was also calculated. Patterns of recent forest development differed between soil trophic groups. Afforestation occurred mainly on wet and poor soils in the 19th and 20th centuries, while the proportion of woodland area on fertile soils typical for nemoral forests was fairly stable. Only 1% of the fertile soil area has been c…
Disrupting immune regulation incurs transient costs in male reproductive function.
2014
9 pages; International audience; BACKGROUND: Immune protection against pathogenic organisms has been shown to incur costs. Previous studies investigating the cost of immunity have mostly focused on the metabolic requirements of immune maintenance and activation. In addition to these metabolic costs, the immune system can induce damage to the host if the immune response is mis-targeted or over-expressed. Given its non-specific nature, an over-expressed inflammatory response is often associated with substantial damage for the host. Here, we investigated the cost of an over-expressed inflammatory response in the reproductive function of male mice. METHODOLOGY/PRINCIPAL FINDINGS: We experimenta…
Infectious transfer of a fertility factor inStreptomyces coelicolor
1973
SUMMARYInitial Fertility (IF) strains ofStreptomyces coelicolorare able to convert recipient strains (UF) to the IF condition by contact, without concomitant transfer of chromosomal markers. The conversion is prevented by the presence of acridine orange in the medium of the mixed culture. Acridine orange is also moderately effective in inducing the formation of UF variants from IF-treated strains. No effect of the drug is observed on UF variant formation from Normal Fertility (NF) strains nor on the behaviour of the fertility factor in NF × UF mixed cultures. The hypothesis is put forward that the fertility factor works as an episome inS. coelicolor, fixed to the chromosome in the NF strain…
Assisted reproductive technology results: Why are live-birth percentages so low?
2014
The present bioessay aims to analyze the impact of parental age, cause of infertility, embryo chromosomal anomalies, assisted reproduction technology (ART) treatments, and environmental and occupational exposures to xenobiotics on ART results, particularly on live-birth percentages per transfer. Special attention is paid to analyzing the effects of these factors on the mitochondrial, genetic, and epigenetic traits of gametes and embryos to ascertain the molecular/cellular mechanisms responsible for the relatively low percentages of live births reported year after year in ART cycles. The bias of age distribution of women attending fertility clinics toward the late thirties and beyond and the…