Search results for "fertility"
showing 10 items of 629 documents
Distribution of soil organic carbon in Wadi Al-Thulaima, Saudi Arabia: A hyper-arid habitat altered by wastewater reuse
2018
The carbon cycle is being altered as a result of human-induced changes in the Earth's system. Therefore, ecosystems such as wetlands, authentic CO2 sinks, are becoming especially important. Little information exits on the soil organic carbon (SOC) stock for the middle east-countries man-made wetlands making wadis permanent with the outflow of wastewater treatment plants. This paper presents the vertical distribution of SOC content, soil bulk density (SBD) and SOC density in soil of vegetated and bare sites in Wadi Al-Thulaima, one of the artificial wetlands in central Saudi Arabia. The mean distribution of SBD in the vegetated and bare sites increased significantly with depth. Inversely, th…
Thyroid disorders in polycystic ovary syndrome
2017
OBJECTIVE: Thyroid disorders, especially Hashimoto’s thyroiditis (HT), are observed significantly more often in patients with polycystic ovary syndrome (PCOS) than in the general population – approximately 27% and 8%, respectively. This is extremely important in young women, because both disorders are connected with fertility problems. As HT and PCOS occur together, fertility problems may become a serious clinical issue in these patients. MATERIALS AND METHODS: A systematic literature review in PubMed of PCOS- and HT-related articles in English, published until December 2015 was conducted. RESULTS: The reasons for joint prevalence still remain unclear. Genetic and autoimmune backgrounds are…
Luteinised unruptured follicle syndrome: pathophysiological background and new target therapy in assisted reproductive treatments
2022
Luteinised unruptured follicle syndrome (LUFS) is a cause of infertility consisting in the unruptured of the dominant follicle after the LH-surge. In fact, during assisted reproductive treatments (ART) clomiphene citrate and letrozole are frequently administered in order to achieve ovulation. However, considering the pathophysiology of LUFS, new possible therapy can be proposed. On this scenario, we performed a review of the literature searching for LUFS recurrency and its impact in infertility and ART. An inflammation theory has been proposed that can be fuel for further therapeutic possibilities. In particular, considering the increase in granulocytes accumulation, the granulocyte colony-…
Rodent plagues, immunocontraception and the mousepox virus
2001
Abstract Rodent plagues cause a major problem for agriculture in many temperate regions, and immunocontraception offers a new method to control fertility in these and other pest vertebrates. However, it is difficult to find an effective carrier for contraceptives for large numbers of pest animals in the field. In a new study, Jackson et al. manipulated the mousepox virus to boost the immune response in infected mice Mus musculus when testing the basis for controlling their fecundity rates. However, all infected mice (and half of recently immunized mice) died. Despite these unexpected and dramatic results of the engineering of mousepox virus, immunocontraception remains the most promising me…
Involvement of SYCP2L and TDRD3 gene variants on ovarian reserve and reproductive outcomes: a cross-sectional study
2023
Objective: Single nucleotide variants have been implicated in the response to fertility treatment and a pharmacogenomic approach may help to customize therapy based on patient genome. We aimed to evaluate the effect, individual and combined, of SYCP2L (rs2153157:G>A) and TDRD3 (rs4886238:G>A) variants on ovarian reserve, response to controlled ovarian stimulation (COS) and reproductive outcomes of women undergoing in vitro fertilization (IVF) treatment. Methods: This cross-sectional study included 149 normoovulatory women undergoing IVF. Genotyping was performed using the TaqMan real-time polymerase chain reaction method. Clinical parameters and reproductive outcomes were compared acc…
Chronic Endometritis
2016
Chronic endometritis is a persistent inflammation of the inner lining of the uterine cavity. Several studies have demonstrated that it is a condition frequently associated with repeated unexplained implantation failure at in vitro fertilization, recurrent miscarriage, as well as poor obstetric outcomes such as preterm labor. The aim of this paper is to provide information about diagnosis and treatment of this condition to improve reproductive outcome. In fact, significantly higher rate of successful pregnancies was achieved in those patients in whom antibiotic treatment was able to normalize both hysteroscopic and histologic endometrial pattern compared with women who were not treated or wi…
How do individual attachment patterns of both members of couples affect their perceived infertility stress? An actor–partner interdependence analysis
2016
Abstract There exists a lack of dyadic research examining how the attachment characteristics of infertile individuals influence their experience of infertility-related distress. The actor partner interdependence model was used to test a theoretical model by examining whether both infertile wives and husbands, who display high levels of attachment avoidance and/or attachment anxiety, will experience infertility-related distress. Seven hundred and seventy individuals (385 couples) completed the experience in close relationships, the fertility problem inventory, and the state-trait anxiety inventory prior to infertility treatment. Wives' distress was predicted by their own and by their husband…
Myomectomy in infertile women: More harm than good?
2023
Adhesion formation following gynecological surgery remains a challenge. The adoption of minimally invasive surgical approaches, such as conventional or robotic-assisted laparoscopy combined with meticulous microsurgical principles and the application of adhesion–reducing substances, is able to reduce the risk of de novo adhesion formation but do not eliminate it entirely. Myomectomy is the most adhesiogenic surgical procedure and postoperative adhesions can have a significant impact on the ability to conceive. Therefore, when surgery is performed as infertility treatment, attention should be paid to whether the benefits outweigh the risks. Among several factors, the size and the location of…
Ovarian Hyperstimulation Syndrome as a Growing Diagnostic Problem in Emergency Department Settings: A Case Report.
2018
Abstract Background Ovarian hyperstimulation syndrome (OHSS) is a common complication of an in-vitro fertilization (IVF) procedure, which is usually clinically insignificant. However, without monitoring, it can progress into a life-threatening condition. With the increasing popularity of IVF technology, patients with OHSS may begin visiting emergency departments (EDs) more frequently. Case Report We report the case of a patient admitted to the ED presenting with severe abdominal pain, cough, and nausea. An ultrasound examination was inconclusive. Computer tomography revealed enlarged ovaries and fluid in the pleural cavities, around the liver and spleen, between the bowel loops, and in the …
First clinical uterus transplantation trial: a six-month report.
2014
Objective To report the 6-month results of the first clinical uterus transplantation (UTx) trial. This type of transplantation may become a treatment of absolute uterine-factor infertility (AUFI). Design Prospective observational study. Setting University hospital. Patient(s) Nine AUFI women and their live uterine donors, the majority being mothers. Intervention(s) Live-donor UTx and low-dose induction immunosuppression. Main Outcome Measure(s) Data from preoperative investigations, surgery and follow-up for 6 months. Result(s) Durations of donor and recipient surgery ranged from 10 to 13 hours and from 4 to 6 hours, respectively. No immediate perioperative complications occurred in any of …