Search results for "fetal programming"
showing 3 items of 13 documents
Early life determinants of frailty in old age : the Helsinki Birth Cohort Stud
2018
Background there is evidence suggesting that several chronic diseases have their origins in utero and that development taking place during sensitive periods may affect the aging process. We investigated whether early life determinants would be associated with frailty in old age. Methods at a mean age of 71 years, 1,078 participants belonging to the Helsinki Birth Cohort Study were assessed for frailty according to the Fried frailty criteria. Early life measurements (birth weight, length, mother body mass index [BMI] and parity) were obtained from birth, child welfare and school health records. Multinomial regression analysis was used to assess the association between early life determinants…
Fetal programming and its effects on vascular pulmonary circulation
2018
Into the scientific community, consensus about the emerging concept of “the fetal origin of adult diseases” is growing. It sustains that the parental (of the two parents) adversities, and the related external influences, during the intra-utero/ perinatal life of each eutherian mammal organism, human included, can permanently set the structure and functionality of specific body systems (i.e., immune, endocrine, nervous and cardiovascular systems), predisposing them to early ageing and disease during adulthood. The pulmonary circulation system also appears to be one of its targets. Established evidence supports the strong association between developmental programming and pulmonary arterial re…
Fetal programming as the cause of all the evils in adult humans: atherosclerosis and coronary heart disease included
2020
〈 Collection 2020/3 About us Imprint Open access Editorial board Contact Vision and mission Services Picture credits Disclaimer Congresses Job vacancies For readers Subscription Current issue Archives Search For authors Guidelines Copyright Submission Article types Supplements For advertisers Media data Portfolio Reader poll Reprints Offer Sales team Collection 2020/3 REVIEW ARTICLE Fetal programming as the cause of all the evils in adult humans: atherosclerosis and coronary heart disease included DOI: https://doi.org/10.4414/cvm.2020.02113 Publication Date: 11.06.2020 Cardiovasc Med. 2020;23:w02113 Balistreri Carmela R. Affiliationskeyboard_arrow_down Summary The theory of David Barker on …