Search results for "finite-element"
showing 2 items of 22 documents
Pre-Operative Modeling of Transcatheter Mitral Valve Replacement in a Surgical Heart Valve Bioprosthesis
2020
Obstruction of the left ventricular outflow tract (LVOT) is a common complication of transcatheter mitral valve replacement (TMVR). This procedure can determine an elongation of an LVOT (namely, the neo-LVOT), ultimately portending hemodynamic impairment and patient death. This study aimed to understand the biomechanical implications of LVOT obstruction in a patient who underwent TMVR using a transcatheter heart valve (THV) to repair a failed bioprosthetic heart valve. We first reconstructed the heart anatomy and the bioprosthetic heart valve to virtually implant a computer-aided-design (CAD) model of THV and evaluate the neo-LVOT area. A numerical simulation of THV deployment was then deve…
3D Printing and Computational Modeling for the Evaluation of LVOT obstruction in Transcatheter Mitral Valve Replacement
2022
Transcatheter mitral valve replacement (TMVR) is an emerging alternative treatment for those patients not qualified for surgery. However, TMVR can determine an obstruction of the left ventricular outflow tract (namely, neo-LVOT) induced by the transcatheter heart valve (THV) displacing the native mitral valve leaflet towards the myocardial wall. This condition can lead to haemodynamic impairment and ultimately patient death. We sought to predict the neo-LVOT obstruction by first developing patient-specific simulations of the THV deployment and then comparing predictions with post-TMVR diagnostic images and 3D printed human models. Using pre-TMVR computed-tomography (CT) imaging, patient-spe…