Search results for "flagellin"

showing 2 items of 12 documents

Identification of the VvFLS2 grapevine flagellin receptor by a functional genomics strategy

2012

[SDE] Environmental Sciencesflagellin receptor[SDV]Life Sciences [q-bio]VvFLS2 grapevine flagellin receptorgrapevinegenomic[SDV] Life Sciences [q-bio]functional[SDE]Environmental Sciences[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyVvFLS2[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyfunctional genomics strategystrategyVvFLS2;grapevine;flagellin receptor;functional;genomic;strategy
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Vascular Adhesion Protein 1 Mediates Gut Microbial Flagellin-Induced Inflammation, Leukocyte Infiltration, and Hepatic Steatosis

2021

Toll-like receptor 5 ligand, flagellin, and vascular adhesion protein 1 (VAP-1) are involved in non-alcoholic fatty liver disease. This study aimed to determine whether VAP-1 mediates flagellin-induced hepatic fat accumulation. The effects of flagellin on adipocyte VAP-1 expression were first studied in vitro. Then, flagellin (100 ng/mouse) or saline was intraperitoneally injected into C57BL/6J (WT) and C57BL/6-Aoc3-/- (VAP-1 KO) mice on a high-fat diet twice a week every 2 weeks for 10 weeks. After that, the effects on inflammation, insulin signaling, and metabolism were studied in liver and adipose tissues. Hepatic fat was quantified histologically and biochemically. Because flagellin cha…

medicine.medical_specialtysuolistomikrobistoAdipose tissueInflammationliver03 medical and health scienceschemistry.chemical_compound0302 clinical medicineAdipocyteInternal medicineMaterials ChemistrymedicineLipolysislcsh:Scienceaineenvaihdunta030304 developmental biology0303 health sciencesbiologygut microbiotatulehdusChemistryFatty livermaksamedicine.diseasebacterial infections and mycosesrespiratory tract diseasesEndocrinologyinflammation030220 oncology & carcinogenesisbiology.proteinlcsh:Qmedicine.symptomSteatosisHepatic fibrosismetabolismFlagellin
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