Search results for "flume"
showing 10 items of 85 documents
Pharmacokinetics, bioavailability and absorption of flumequine in the rat.
1999
Abstract The study demonstrates that the oral extent of bioavailability of flumequine in the rat, relative to the intravenous injection, is complete (0.94±0.04) and not significantly different from that found by the intraduodenal route (0.95±0.04). The rate of oral bioavailability, however, is slow ( k a =1.20±0.07 h −1 ; T max =2.0 h), but enough to maintain plasma levels above the minimal inhibitory concentration of the most common pathogens for an extended period of time (about 10 h). The reason for the oral absorption slowness could be a slow gastric emptying, an adsorption to the gastric mucosae, a precipitation in the gastric medium or any other feature concerning the stomach as the i…
Friction Factor for Gravel-Bed Channel with High Boulder Concentration
2000
This paper reports the results of an experimental investigation on flow resistance law for a gravel-bed channel having bed arrangements characterized by different values of the number of boulders. The dependence is studied of a parameter, proposed for describing the gravel-bed surfaces, on the boulder concentration and on the ratio between the median diameter of the coarser particles and the median diameter of the bed layer. Flume measurements carried out for the hydraulic condition of \Itransition\N and \Ilarge-scale\N roughness (1.5 ≤ \ih/\id\d5\d0 ≤ 6.9) show that the intercept of the semilogarithmic flow resistance law depends on the ratio and on boulder concentration. For concentration…
The influence of roughness geometry and shields parameter on flow resistance in gravel-bed channels
1997
The spatial variability of bed particles of a gravel-bed channel is analysed and treated experimentally in order to simulate the effects of the arrangement of coarse bed elements on the flow resistance law. For the studied bed patterns, characterized by the concentration Γ of coarser elements arranged on the bed layer, a particle arrangement parameter α is proposed. The α parameter is useful for estimating the intercept b0 of the semi-logarithmic flow resistance law deduced by flume measurements carried out for the hydraulic condition of large-scale and transition roughness. The differences between the experimental friction factor parameter values and the ones calculated by the proposed sem…
Experimental study on triangular central baffle flume
2019
Abstract In this paper the results of the experiments performed to study the flow through a Triangular Central Baffle Flume (TCBF) are reported. The investigated flume consists of a triangular baffle of the apex angle of 75° with a given base width. The theoretical stage-discharge formula was deduced by applying the Buckingham's Theorem and incomplete self-similarity hypothesis and was calibrated using the laboratory measurements carried out in this investigation. The proposed stage-discharge formula is characterized by a mean absolute relative error of 7.4% and 72% of the data points are in an error range of ±5%. The results indicate that TCBF flume is characterized by a flow capacity high…
Experimental Analysis of Horizontal Turbulence of Flow over Flat and Deformed Beds
2015
Abstract Laboratory experiments in a straight flume were carried out to examine the evolution of large-scale horizontal turbulent structures under flat-bed and deformed-bed conditions. In this paper, the horizontal turbulence of flow under these conditions is analyzed and compared. The conditioned quadrant method is applied to verify the occurrence of turbulent events. The distributions of horizontal Reynolds shear stress and turbulent kinetic energy are also presented and discussed. Results show the occurrence of an “initial” sequence of horizontal vortices whose average spatial length scales with the channel width. Under deformed-bed conditions, this spatial length does not change.
Turbulence structure and implications in exchange processes in high-amplitude vegetated meanders: Experimental investigation
2018
Aquatic plants in rivers interact with flow and exert an important role in maintaining suitable habitat and ecological equilibrium. Understanding turbulence structure in the presence of vegetation is important with respect to environmental processes, such as sediment transport and mixing of transported quantities. Literature indicates that mass and momentum exchanges in the presence of vegetation are strongly influenced by the sequence of coherent structures which form between vegetated and non-vegetated zones. In the present paper we investigate turbulence structure and coherent motion in high-curvature channels with submerged vegetation. The analysis is performed with the aid of detailed …
Plasmid-mediated QnrS2 determinant from a clinical Aeromonas veronii isolate.
2008
The main objective of this study was to determine the prevalence of the Qnr determinants in clinical and environmental Aeromonas spp. A total of 52 Aeromonas sp. isolates identified by biochemical methods (5), 25 isolated from natural waters (1) and 27 isolated from clinical samples from hospitals in Valencia, Spain, were tested for quinolone resistance by the disk diffusion method (4) (nalidixic acid, 30 μg; oxolinic acid, 2 μg; flumequine, 30 μg; ciprofloxacin, 5 μg; and levofloxacin, 5 μg). Among the studied isolates, 27 showed resistance to nalidixic acid and susceptibility to ciprofloxacin, 24 isolates were susceptible to both nalidixic acid and ciprofloxacin, and only 1, the A. veroni…
Hydrodynamics of periodic breathers
2014
We report the first experimental observation of periodic breathers in water waves. One of them is Kuznetsov–Ma soliton and another one is Akhmediev breather. Each of them is a localized solution of the nonlinear Schrödinger equation (NLS) on a constant background. The difference is in localization which is either in time or in space. The experiments conducted in a water wave flume show results that are in good agreement with the NLS theory. Basic features of the breathers that include the maximal amplitudes and spectra are consistent with the theoretical predictions.
Testing the stage-discharge relationship of a sharp crested sluice gate deduced by the momentum equation for a free-flow condition
2018
Abstract In this paper the stage-discharge relationship of a sharp crested sluice gate is deduced by applying the momentum equation for a free flow condition. The theoretically deduced stage-discharge formula was then calibrated using experimental flume data obtained in previous investigations carried out for a free-flow condition. The deduced stage–discharge relationship is characterized by a momentum coefficient which is empirically estimated by the ratio between the height of the orifice and the water depth in the section upstream the gate. The relative errors are always less than or equal to - 10% to +10% and 71.4% of the errors are less than or equal to ± 2%.
Analysis of Urine Samples Containing Cardiovascular Drugs by Micellar Liquid Chromatography with Fluorimetric Detection
1999
A simple direct injection chromatographic procedure with fluorimetric detection is successfully applied to the determination of mixtures of 4 diuretics (amiloride, bendroflumethiazide, piretanide, and triamterene) and 6 beta-blockers (acebutolol, atenolol, labetalol, metoprolol, nadolol, and propranolol), which are usually administered in combinations for the treatment of hypertension, in urine samples. The procedure makes use of C18 columns and micellar mobile phases of sodium dodecyl sulphate (SDS), propanol, and phosphate buffer at pH 3. The adequate resolution of most drugs is obtained with a chemometrics approach where the retention is modeled as a first step using the retention factor…