Search results for "focused ultrasound"

showing 10 items of 37 documents

Combining split-and-merge and multi-seed region growing algorithms for uterine fibroid segmentation in MRgFUS treatments

2016

Uterine fibroids are benign tumors that can affect female patients during reproductive years. Magnetic resonance-guided focused ultrasound (MRgFUS) represents a noninvasive approach that uses thermal ablation principles to treat symptomatic fibroids. During traditional treatment planning, uterus, fibroids, and surrounding organs at risk must be manually marked on MR images by an operator. After treatment, an operator must segment, again manually, treated areas to evaluate the non-perfused volume (NPV) inside the fibroids. Both pre- and post-treatment procedures are time-consuming and operator-dependent. This paper presents a novel method, based on an advanced direct region detection model, …

SpeedupUterine fibroidsImage ProcessingBiomedical EngineeringThermal ablation02 engineering and technologyMagnetic Resonance Imaging InterventionalFocused ultrasound030218 nuclear medicine & medical imaging03 medical and health sciencesComputer-Assisted0302 clinical medicineImage Processing Computer-Assisted0202 electrical engineering electronic engineering information engineeringmedicineHumansSegmentationRadiation treatment planningSplit-and-merge segmentationSettore ING-INF/05 - Sistemi Di Elaborazione Delle InformazioniMRgFUS treatmentsInterventionalLeiomyomaMulti-seed adaptive region growingbusiness.industrymedicine.diseaseMagnetic Resonance Imagingfemale genital diseases and pregnancy complicationsComputer Science ApplicationsAutomatic segmentation MRgFUS treatments Multi-seed adaptive region growing Split-and-merge segmentation Uterine fibroids Algorithms Female High-Intensity Focused Ultrasound Ablation Humans Leiomyoma Magnetic Resonance Imaging Magnetic Resonance Imaging Interventional Image Processing Computer-AssistedMRgFUS treatmentRegion growingAutomatic segmentation; MRgFUS treatments; Multi-seed adaptive region growing; Split-and-merge segmentation; Uterine fibroids; Algorithms; Female; High-Intensity Focused Ultrasound Ablation; Humans; Leiomyoma; Magnetic Resonance Imaging; Magnetic Resonance Imaging Interventional; Image Processing Computer-AssistedHigh-Intensity Focused Ultrasound AblationFemale020201 artificial intelligence & image processingAutomatic segmentationbusinessMerge (version control)AlgorithmAlgorithmsUterine fibroidsMedical & Biological Engineering & Computing
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MRgFUS results Italy

2017

PURPOSE: To present our preliminary results achieved with the first Italian installation of a trans-cranial MRI-guided Focused Ultrasound Surgery (tcMRgFUS) certified system for functional neurosurgery. Moreover, to our knowledge, this is the world-first tcMRgFUS system ever installed on a 1.5T MRI unit. Technical issues faced to achieve a safe and effective treatment will be discussed focusing on MR high-resolution live imaging and thermometry sequences optimization. METHOD AND MATERIALS: Patient enrollment was based on indication for functional neurosurgery and evidence of medication-refractory disease; a detailed medical history has been collected together with a complete clinical examin…

Stereotaxic TechniquesBrain; High-Intensity Focused Ultrasound ablation; Magnetic Resonance Imaging Interventional; Minimally Invasive Surgical Procedures; Stereotaxic TechniquesHigh-Intensity Focused Ultrasound ablationSettore MED/27 - NeurochirurgiaBrainSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaMinimally Invasive Surgical ProcedureMagnetic Resonance Imaging InterventionalSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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MR-guided focused ultrasound application for moving target tumor ablation in abdominal area: Coil selection

2020

PubMed: 32276552

SwineThermal ablationMagnetic Resonance Imaging InterventionalTumor ablationFocused ultrasound030218 nuclear medicine & medical imagingMagnetic resonance guided focused ultrasound surgery03 medical and health sciencesCE marking0302 clinical medicineEcho planar imagingAbdomenAnimalsHumansMedicineRadiology Nuclear Medicine and imagingRadiological and Ultrasound TechnologyEcho-Planar ImagingPhantoms Imagingbusiness.industryCoils magnetic resonance thermometry tracking echo planar imaging magnetic resonance-guided focused-ultrasound surgery CE marking validation verificationTrackingLiver NeoplasmsVerificationSettore MED/37 - NeuroradiologiaCoilsGeneral MedicineFocused ultrasound surgeryDisease Models AnimalLiverMagnetic resonance thermometryElectromagnetic coil030220 oncology & carcinogenesisHigh-Intensity Focused Ultrasound AblationbusinessSettore MED/36 - Diagnostica Per Immagini E RadioterapiaMri guidedMagnetic resonance thermometryBiomedical engineering
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[Non-invasive trans-cranial magnetic resonance imaging-guided focused ultrasounds surgery to treat neurologic disorders]

2016

Negli anni passati le applicazioni non invasive degli ultrasuoni focalizzati guidati da risonanza magnetica per il trattamento dei disordini neurologici sono state osta- colate da limiti tecnici oggi finalmente superati. In Italia, nel corso del 2015, sono stati effettuati i primi trattamenti utilizzando per la prima volta al mondo un comune scanner di risonanza magnetica da 1.5T. I risultati a oggi ottenuti con questa nuova metodica e le sue future possibili appli- cazioni sono molto promettenti e aprono la strada verso nuove opzioni terapeutiche, sicure ed efficaci, un tempo impensabili. In past years non-invasive clinical applications of magnetic resonance-guided focused ultrasound for t…

Treatment OutcomeItalySettore MED/27 - NeurochirurgiaHumansHigh-Intensity Focused Ultrasound AblationSettore MED/37 - NeuroradiologiaNervous System DiseasesMagnetic Resonance ImagingHuman
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Direct activation of zebrafish neurons by ultrasonic stimulation revealed by whole CNS calcium imaging

2020

Abstract Objective. Ultrasounds (US) use in neural engineering is so far mainly limited to ablation through high intensity focused ultrasound, but interesting preliminary results show that low intensity low frequency ultrasound could be used instead to modulate neural activity. However, the extent of this modulatory ability of US is still unclear, as in in vivo studies it is hard to disentangle the contribution to neural responses of direct activation of the neuron by US stimulation and indirect activation due either to sensory response to mechanical stimulation associated to US, or to propagation of activity from neighboring areas. Here, we aim to show how to separate the three effects and…

Ultrasonic Therapy0206 medical engineeringBiomedical EngineeringCalcium imagingStimulationSensory systembrain-stimulation02 engineering and technologysystem03 medical and health sciencesCellular and Molecular NeuroscienceUltrasounds0302 clinical medicineCalcium imagingmedicineAnimalsZebrafishZebrafishNeuronscalcium imaging ultrasonic stimulation ultrasound zebrafishSensory stimulation therapybiologyCalcium imaging; Neuromodulation; Ultrasounds; ZebrafishNeuromodulationneuromodulation; zebrafish; ultrasounds; calcium imagingtranscranial focused ultrasoundNeural engineeringbiology.organism_classification020601 biomedical engineeringNeuromodulation (medicine)cellular resolutionmedicine.anatomical_structureLarvaCalciumNeuronNeuroscience030217 neurology & neurosurgeryneurostimulation
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TRANS-FUSIMO – A novel system for treatment support for FUS applications in moving abdominal organs

2018

Computer based treatemnt support for FUS therapy of moviving abdominal organs is essential due to great intrinsic challenges: the target moves due to breathing and may be occluded by the rib cage. In the EU project TRANS-FUSIMO we have developed a sophisticated software system that connects to a FUS transducer and an MRI. This enables physicians to conduct safe, effective and efficient ablation of tumors in the moving liver.

abdominal organs focused ultrasounds softwareSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Trans-cranial Magnetic Resonance-guided Focused UltraSound (tcMRgFUS) system integrated with a 1.5T: an SNR study on DQA phantoms

2018

Background: In recent years transcranial Magnetic Resonance-guided Focused Ultrasound Surgery (tcMRgFUS) treatments have been performed only using 3T units. Since following some internal analysis, planning images obtained using a 1.5T MRI’s body RF coil (as usually done with 3T systems) showed generally reasonable quality in terms of anatomy visualization and SNR but thermal images noise was above acceptable standard for treatments, a dedicated 2-channels head coil was developed (InSightec Ltd.) to ensure an adequate signal-to-noise ratio (SNR). Hence, we present the imaging protocol and the technological methods successfully used with the world-first installation of a certified tcMRgFUS sy…

dose quality assurance phantom focused ultrasound SNR MRISettore MED/37 - NeuroradiologiaSettore MED/36 - Diagnostica Per Immagini E RadioterapiaSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)
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MAGNETIC RESONANCE IMAGING–GUIDED FOCUSED ULTRASOUND THALAMOTOMY IN PATIENT WITH TREMOR COMBINED WITH PARKINSONISM: RETREATMENT AFTER BENEFIT DECAY

2019

Background In recent years, transcranial Magnetic Resonance-guided Focused UltraSounds (tcMRgFUS) treatments for functional neurological disorders are giving a new thrust to the field of therapeutic brain lesioning. This technique has been proven safe and effective in selected patients. Here we present the case of a patient affected by tremor combined with parkinsonism who underwent a second tcMRgFUS thalamotomy because of relapsing tremor after a few months from the first tcMRgFUS treatment. Materials and Methods A 72-year-old, right-handed man, who came to our observation because of a disabling tremor affecting mainly his upper right limb and refusing any invasive surgical procedure. His …

focused ultrasound Parkinsonism thalamotomy thermal ablation retreatemtnSettore MED/27 - NeurochirurgiaSettore MED/37 - NeuroradiologiaSettore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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TRANS-FUSIMO: preliminary in-vivo animal results of MR-guided focused ultrasound of liver under respiratory motion

2019

Purpose: Treating liver tumors using Focused Ultrasound (FUS) is a great challenge. Prior to human applications, an in-vivo animal trial using the TRANS-FUSIMO treatment system (TTS) is ongoing in order to evaluate the safety and the technical efficacy and efficiency of generating predefined necrotic lesions. Methods and Materials: The trial includes a crossbred porcine model of thirty large white swine (all females; 55-85Kg) that will be treated using the TTS under general anaesthesia with intubation. All treatments haven been performed under ventilator-controlled breathing and using an improved non-clinical prototype FUS transducer integrated with a 1,5T MRI unit; a set of interventional …

focused ultrasound liver motion tracking interventional radiology interventional magnetic resonance imagingSettore MED/36 - Diagnostica Per Immagini E Radioterapia
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Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) for uterine fibroids: our experience on patients’ eligibility

2014

Learning objectives Background Findings and procedure details Conclusion Personal information References

genetic structuresNeoplasiaMagnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) uterine fibroids eligibilityeducationUltrasoundAbdomenSettore MED/50 - Scienze Tecniche Mediche ApplicateMRMultidisciplinary cancer careSettore MED/36 - Diagnostica Per Immagini E RadioterapiaAblation proceduresGenital / Reproductive system female
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