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showing 10 items of 7082 documents

Does Hybrid Surgery Improve Quality of Life in Multilevel Cervical Degenerative Disk Disease? Five-Year Follow-up Study.

2020

Background: Patient satisfaction is becoming an increasing factor worthy of consideration when evaluating the surgical quality. The correlation between patient satisfaction and surgical outcomes 5 years after cervical hybrid surgery (HS), which incorporates anterior cervical decompression and fusion and cervical disk arthroplasty techniques in multilevel cervical degenerative disk disease, has not been evaluated. Methods: The aim of this study was firstly to analyze prospectively collected data from a sample of patients (n = 50) treated with cervical HS for selected cases of radiculopathy and myelopathy in order to evaluate pain levels of patients, using the Neck and Arm Pain scale as an ex…

AdultMalemedicine.medical_specialtyTotal Disc ReplacementVisual analogue scalemedicine.medical_treatmentDiseaseIntervertebral Disc DegenerationFunctional score03 medical and health sciencesMyelopathyAnterior cervical diskectomy fusion0302 clinical medicinePatient satisfactionPostoperative ComplicationsQuality of lifemedicineHumansRadiculopathyAgedbusiness.industryPain scaleMiddle AgedArtificial disk replacementmedicine.diseaseDecompression SurgicalArthroplastyCombined Modality TherapyMagnetic Resonance ImagingSurgerySpinal FusionTreatment OutcomePatient Satisfaction030220 oncology & carcinogenesisOrthopedic surgeryCervical VertebraeQuality of LifeSurgeryFemaleNeurology (clinical)businessDeglutition DisordersSpinal Cord CompressionHybrid surgery030217 neurology & neurosurgeryFollow-Up StudiesWorld neurosurgery
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Survival in young patients with intermediate-/high-risk myelofibrosis: Estimates derived from databases for non transplant patients

2009

Recent studies have suggested that allogenic stem cell transplantation (allo-SCT) might be a better treatment option, compared to drug therapy, for young patients with high-/intermediate-risk primary myelofibrosis (PMF). However, there are no controlled studies that validate this contention and allo-SCT is associated with a substantial risk of procedure-related mortality and morbidity. In a retrospective analysis of nontransplant PMF patients, who were both young (age <60 years) and with high-/intermediate-risk disease, 1- and 3-year survival estimates were 87% and 55%, 95% and 77%, 71% and 58%, respectively, involving patients seen at three different centers with expertise in PMF; these da…

AdultMalemedicine.medical_specialtyTransplantation ConditioningAdolescentmedicine.medical_treatmentbone marrow transplantationContext (language use)myelofibrosisHematopoietic stem cell transplantationKaplan-Meier EstimateSettore MED/15 - Malattie Del Sanguemyelofibrosis survivalYoung AdultPharmacotherapyInternal medicinemedicineHumansTransplantation HomologousYoung adultMyelofibrosisRetrospective Studiesbusiness.industryAge FactorsHematopoietic Stem Cell TransplantationRetrospective cohort studyHematologyMiddle Agedmedicine.diseaseSurgeryTransplantationmyelofibrosis; bone marrow transplantationPrimary MyelofibrosisFemaleTransplantation ConditioningbusinessFollow-Up Studies
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Reduced intensity conditioning HLA identical sibling donor allogeneic stem cell transplantation for patients with follicular lymphoma: long-term foll…

2010

Background Allogeneic hematopoietic stem cell transplantation is an effective treatment for patients with poor risk lymphoma, at least in part because of the graft-versus-lymphoma effect. Over the past decade, reduced intensity conditioning regimens have been shown to offer results similar to those of conventional high-dose conditioning regimens but with lower toxicity early after transplantation, especially in patients with chemosensitive disease at transplant. Design and Methods The aim of this study was to analyze the long-term outcome of patients with follicular lymphoma who received an HLA identical sibling allogeneic stem cell transplant with a reduced intensity conditioning regimen w…

AdultMalemedicine.medical_specialtyTransplantation Conditioningmedicine.medical_treatmentFollicular lymphomaHematopoietic stem cell transplantationGastroenterologyreduced intensity conditioningfollicular lymphomaallogeneic stem cell transplantationInternal medicinemedicinegraft-versus-host diseaseHumansTransplantation HomologousLymphoma FollicularSurvival ratebusiness.industryHistocompatibility TestingSiblingsHematopoietic Stem Cell TransplantationHematologyMiddle Agedmedicine.diseaseSurgeryFludarabineSurvival RateTransplantationTreatment OutcomeGraft-versus-host diseaseFemaleOriginal ArticleTransplantation ConditioningbusinessProgressive diseaseFollow-Up Studiesmedicine.drugHLA identical sibling donor
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Prediction of symptom remission in schizophrenia during inpatient treatment

2007

Standardized consensus criteria for remission in schizophrenia were recently proposed. The present study applied the symptom-severity component of these criteria to a sample of inpatients in order to determine the rates of remission during inpatient treatment and to explore predictors of remission.A total of 288 inpatients from a multi-centre follow-up programme who fulfilled ICD-10 criteria for schizophrenia were included in the present analyses. PANSS ratings at admission and at discharge from hospitalization were used to examine remission status. Clinical and sociodemographic variables at admission were tested for their ability to predict remission at discharge.In total, 55% of the sampl…

AdultMalemedicine.medical_specialtyTreatment outcomeConsensus criteriaLogistic regressionYoung Adult03 medical and health sciences0302 clinical medicineInternational Classification of DiseasesGermanyInternal medicineInterview PsychologicalmedicineHumansYoung adultPsychiatryBiological PsychiatryPsychiatric Status Rating ScalesModels StatisticalFollow up studiesMiddle AgedPrognosismedicine.disease030227 psychiatryHospitalizationPsychiatry and Mental healthTreatment OutcomeROC CurveMulticenter studySchizophreniaPsychiatric status rating scalesSchizophreniaFemaleSchizophrenic PsychologyPsychology030217 neurology & neurosurgeryFollow-Up StudiesThe World Journal of Biological Psychiatry
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Free style facial artery perforator flap for one stage reconstruction of the nasal ala.

2007

Summary The nasolabial skin is the ideal donor site for nasal ala reconstruction. The classic techniques involve a two-stage procedure to reconstruct an aesthetically pleasing nasal ala. A one-stage technique for reconstruction of the nasal ala with a free style nasolabial perforator flap is presented in this article. Patients and methods The technique has been used in eight patients between November 2004 and June 2007. In most of the cases (seven out of eight) the whole alar subunit was reconstructed. Results Besides a small distal 2mm necrosis in one flap – which healed without further treatment – all the flaps healed uneventfully with aesthetically pleasing results using the one-stage te…

AdultMalemedicine.medical_specialtyTreatment outcomeNose NeoplasmsSensationFacial arteryFree flapSurgical Flapsnose reconstructionmedicine.arteryfree style flapperforatorMedicineHumansNose reconstructionNosefacial arteryAgedAged 80 and overbusiness.industryFollow up studiesOne stageAnatomyRhinoplastySurgeryNasal alamedicine.anatomical_structureTreatment OutcomeCarcinoma Basal CellCarcinoma Squamous CellSurgeryFemalebusinessFollow-Up Studies
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Sudden Sensorineural Hearing Loss: Results of intratympanic steroids as salvage treatment

2012

Objective: The aim of the present study was to verify the efficacy and the safety of intratympanic dexamethasone to treat sudden sensorineural hearing loss as salvage therapy. Materials and methods: A prospective study was conducted on patients affected by idiopathic sudden hearing loss who were treated before with some systemic therapy, but without recovery of the hearing The patients able to undergo the study, but who refused salvage treatment were considered as control group. A solution of Dexamethasone 4 mg/ml was then injected through the posterior–inferior quadrant filling completely the middle ear. The follow-up in the following 6 months included an audiogram every month. Results: Th…

AdultMalemedicine.medical_specialtyTympanic MembraneAdolescentNeurosensorial Hearing Loss Steroids treatmentHearing lossHearing Loss SensorineuralSalvage therapyInjections IntralesionalAudiologyRisk AssessmentSystemic therapyDexamethasoneYoung AdultConfidence IntervalsOdds Ratiootorhinolaryngologic diseasesmedicineHumansProspective StudiesProspective cohort studyDexamethasoneAgedSalvage TherapyAnalysis of VarianceAbsolute threshold of hearingmedicine.diagnostic_testbusiness.industryAudiogramHearing Loss SuddenMiddle AgedTreatment OutcomeSettore MED/31 - OtorinolaringoiatriaOtorhinolaryngologyCase-Control StudiesAnesthesiaAudiometry Pure-ToneFemaleAudiometrymedicine.symptombusinessFollow-Up Studiesmedicine.drugAmerican Journal of Otolaryngology
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Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy: a randomized clinical study.

2011

The aim of this study was to verify the efficacy and the safety of transtympanic dexamethasone to treat sudden sensorineural hearing loss as first and single drug method. Considering ethical implication of performing a mininvasive procedure on middle ear, we matched such proposed treatment with systemic prednisone administration that represents the widest adopted protocol. Randomized prospective study was conducted. The inclusion criterion was a sudden sensorineural hearing loss of at least 30 dB across three contiguous frequencies over a period of 24 h. Group A received transtympanic steroid injections; Group B received oral administration of steroids. 25 patients were treated with transty…

AdultMalemedicine.medical_specialtyTympanic MembraneHearing Loss SensorineuralAdministration OralInjections IntralesionalRisk AssessmentSeverity of Illness IndexDexamethasoneDrug Administration ScheduleAudiometryOral administrationPrednisoneSeverity of illnessmedicineHumansProspective StudiesProspective cohort studyDexamethasoneAgedAnalysis of Variancemedicine.diagnostic_testDose-Response Relationship Drugbusiness.industryGeneral MedicineHearing Loss SuddenMiddle AgedSurgeryCochlea Deafness Round window Sudden sensorineural hearing loss Steroid TranstympanicTreatment OutcomeOtorhinolaryngologyOtorhinolaryngologyFemaleNeurosurgeryAudiometrybusinessmedicine.drugFollow-Up Studies
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Treatment of Ménière's disease by low-dosage intratympanic gentamicin application: effect on otolith function.

2007

Objectives: The intratympanic application of a low dosage of gentamicin is increasingly favored as treatment for Meniere's disease. While posttreatment observations have confirmed a long-term success of the therapy of vertigo attacks, clear differences in the posttreatment recovery interval can be observed. In addition to differences in central-vestibular compensation, the degree of peripheral vestibular damage, i.e., to the saccule, utricle, and semicircular canal ampullae, varies among patients. This study provides comprehensive pre- and posttreatment results from unilateral functional tests of the individual vestibular receptors and of the cochlea in patients with Meniere's disease. Stud…

AdultMalemedicine.medical_specialtyTympanic MembraneVestibular evoked myogenic potentialAdministration TopicalOtolithic MembraneUtricleVertigootorhinolaryngologic diseasesmedicineHumansProspective StudiesMeniere DiseaseAntibacterial agentAgedVestibular systemSemicircular canalbiologyDose-Response Relationship Drugbusiness.industryElectromyographymedicine.diseasebiology.organism_classificationSurgeryAnti-Bacterial Agentsmedicine.anatomical_structureTreatment OutcomeOtorhinolaryngologyAnesthesiaEvoked Potentials AuditoryFemalesense organsSacculeGentamicinsbusinessMeniere's diseaseFollow-Up StudiesThe Laryngoscope
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Shock-wave therapy for tennis and golfer's elbow - 1 year follow-up

1999

Thirty patients with chronic medial epicondylitis were treated with low-energy shock waves. They received 500 impulses of 0.08 mJ/mm2 three times at weekly intervals. At 1 year follow-up examinations were performed. According to the Verhaar criteria, only seven patients reached excellent or good results. In eight cases a fair outcome was recorded, and in 14 patients the outcome was poor. Only six patients were satisfied with the treatment. The average relief of pain was 32%. These data were significantly worse than for identically treated patients with chronic tennis elbow. Thus, the question arises as to whether extracorporal shock-wave therapy is indicated in medial epicondylitis.

AdultMalemedicine.medical_specialtyUltrasonic TherapyElbowTennis injuriesElbow JointmedicineTennis elbowHumansGolfer's elbowOrthopedics and Sports MedicineRange of Motion ArticularAgedPain MeasurementHand Strengthbusiness.industryEpicondylitisTennis ElbowEquipment DesignGeneral MedicineMiddle Agedmedicine.diseaseSurgeryTreatment Outcomemedicine.anatomical_structureTennisChronic DiseaseOrthopedic surgeryPhysical therapyGolfUpper limbFemaleSurgerybusinessRange of motionFollow-Up StudiesArchives of Orthopaedic and Trauma Surgery
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Durability of open popliteal artery aneurysm repair

2014

Objective The objective of this study was to analyze our long-term results after open surgery for popliteal artery aneurysm. Methods Records of patients who received surgery between 1998 and 2010 were retrieved from a computerized database and analyzed retrospectively. End points of the study were perioperative mortality and morbidity and patency and limb salvage rate. Results Two hundred and six popliteal aneurysms (median diameter, 30 mm; interquartile range, 18 mm) were treated (161 elective, 45 emergent) in 154 patients (mean age, 67 ± 11 years) using vein grafts (82%) via the medial approach (92%). Above-knee popliteal artery (45%) and below-knee popliteal artery (65%) were the predomi…

AdultMalemedicine.medical_specialtyUmbilical VeinsLimb salvageVein graftInterquartile rangemedicine.arteryMedicineHumansPopliteal ArteryAgedRetrospective StudiesComputerized databasesAged 80 and overUltrasonography Doppler Duplexbusiness.industryOpen surgeryAnastomosis SurgicalPopliteal artery aneurysmAngiography Digital SubtractionPerioperativeMiddle AgedPlastic Surgery ProceduresAneurysmPopliteal arterySurgeryTreatment OutcomeAnesthesiaFemaleSurgerybusinessCardiology and Cardiovascular MedicineVascular Surgical ProceduresMagnetic Resonance AngiographyFollow-Up StudiesForecastingJournal of Vascular Surgery
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