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showing 10 items of 7082 documents

Design and Baseline Characteristics of the HELP Study: An Extended and Long-Term Observation of Pathological Myopia in Caucasians.

2017

<b><i>Purpose:</i></b> To assess the natural disease progression of high myopia in Caucasians considered at risk for the development of myopic choroidal neovascularization (mCNV). <b><i>Methods:</i></b> Subjects were recruited in 25 clinical sites between June 2014 and June 2016. Main inclusion criteria included axial length of ≥26 mm, best-corrected visual acuity ≥0.05 decimal equivalent and presence of at least one out of five predefined morphological disease risk criteria. These were (1) subfoveal choroidal thinning < 50 µm, (2) enhanced choroidal curvature length > 6,300 µm, (3) lacquer cracks, (4) patchy atrophy &#x3…

AdultMalemedicine.medical_specialtyVisual acuityVisual AcuityDiseaseWhite People03 medical and health sciencesYoung Adult0302 clinical medicineAtrophyMyopic choroidal neovascularizationOphthalmologySurveys and QuestionnairesmedicineHumansProspective StudiesFluorescein AngiographyAgedAged 80 and overbusiness.industryChoroidPathological myopiaGeneral MedicineMiddle Agedmedicine.diseaseeye diseasesSensory SystemsChoroidal NeovascularizationClinical trialNatural historyOphthalmologyAxial Length EyeResearch DesignBaseline characteristicsMyopia Degenerative030221 ophthalmology & optometryDisease ProgressionFemalesense organsmedicine.symptomAtrophybusiness030217 neurology & neurosurgeryTomography Optical CoherenceFollow-Up StudiesOphthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
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Central retinal vein occlusion in young people.

1992

In a study performed on 20 subjects with central retinal vein occlusion (CRVO) aged 40 years or less we found the ischemic form in 20%. Disc edema was a common finding at the onset, while macular edema was less frequently seen. Systemic or ocular disorders that could be related with the development of the CRVO were often found; a patient was affected with myasthenia gravis and another with Sturge-Weber syndrome: these two diseases were not previously reported in association with CRVO. In only two of the 11 patients followed-up the visual acuity improved. The visual prognosis in CRVO of young people is often poor; the more frequent cause of the reduced visual acuity is chronic cystoid macula…

AdultMalemedicine.medical_specialtyVisual acuitygenetic structuresAdolescentEye diseaseIschemiaVisual AcuityCentral retinal vein occlusionIschemiaPhysiology (medical)OphthalmologyEdemaRetinal Vein OcclusionmedicineHumansYoung adultMacular edemabusiness.industrymedicine.diseasePrognosiseye diseasesSensory SystemsSurgeryOphthalmologyFemalesense organsmedicine.symptombusinessRetinopathyFollow-Up StudiesDocumenta ophthalmologica. Advances in ophthalmology
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Intravitreal clindamycin and dexamethasone for zone 1 toxoplasmic retinochoroiditis at twenty-four months.

2009

Purpose To report the anatomic and functional outcomes of intravitreal clindamycin and dexamethasone for the treatment of zone 1 toxoplasmic retinochoroiditis (TRC). Patients had 1 or more of the following indications for local therapy: intolerance to oral medication, contraindication to oral medication because of pregnancy, lack of response despite oral antimicrobial treatment, or treatment with concomitant oral and local therapy to avoid or limit foveal or optic disc involvement. Design Noncomparative, retrospective, multicentric interventional case series. Participants We reviewed the medical records of 12 consecutive patients (eyes) with posterior pole (zone 1) TRC who were treated week…

AdultMalemedicine.medical_specialtyVisual acuitygenetic structuresEye diseasePosterior poleAntiprotozoal AgentsVisual AcuityDexamethasoneInjectionsYoung AdultPregnancymedicineHumansFluorescein AngiographyToxoplasmosis OcularContraindicationGlucocorticoidsAntibacterial agentRetrospective Studiesmedicine.diagnostic_testbusiness.industryClindamycinDiabetic retinopathyMiddle Agedmedicine.diseaseFluorescein angiographyeye diseasesSurgeryVitreous BodyOphthalmologyTreatment OutcomeChorioretinitisPregnancy Complications ParasiticDrug Therapy CombinationFemalesense organsmedicine.symptombusinessTomography Optical CoherenceRetinopathyFollow-Up StudiesOphthalmology
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State anxiety and depression as factors modulating and influencing postoperative pain in dental implant surgery. A prospective clinical survey

2013

Objetives: To determine whether preoperative state anxiety and depression modulate or influence objective and subjective postoperative pain following dental implant insertion. Study Design: Prospective, clinical study with 7-day follow-up of a sample of 105 subjects who preoperatively completed the state anxiety questionnaire (STAI-E) and Beck Depression Inventory (BDI) and postoperatively, at 2 and 7 days, recorded objective pain with the Semmes-Weinstein mechanical esthesiometer (SW test) and subjective pain with the Visual Analog Scale (VAS). Results: 85.6% and 81.5% of patients, respectively, recorded no signs of state anxiety or depression. The correlation between anxiety and depressio…

AdultMalemedicine.medical_specialtyVisual analogue scalemedicine.medical_treatmentPostoperative painOdontologíaAnxietyYoung AdultmedicineHumansProspective StudiesYoung adultDental implantProspective cohort studyGeneral DentistryDepression (differential diagnoses)AgedAged 80 and overDental ImplantsPain PostoperativeDepressionbusiness.industryResearchBeck Depression InventoryMiddle AgedMedically compromised patients in Dentistry:CIENCIAS MÉDICAS [UNESCO]Health SurveysCiencias de la saludOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASPhysical therapyAnxietyFemaleSurgerymedicine.symptombusinessFollow-Up StudiesMedicina Oral Patología Oral y Cirugia Bucal
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Presentation, Management and Long-Term Outcome of Ureteropelvic Junction Obstruction in Duplex Kidneys.

2015

Ureteropelvic junction obstruction in association with a duplex collecting system is a rare but challenging upper urinary tract pathology. We report our 21-year experience with this anomaly in terms of presentation, diagnostic evaluation and management.We retrospectively identified all patients with ureteropelvic junction obstruction in a duplex collecting system between 1991 and 2012. We reviewed each case for presenting symptoms, anatomy and management. Median followup was 10.8 years (range 2 to 22).Ureteropelvic junction obstruction in duplex kidneys was diagnosed in 21 patients. Ten patients presented with clinical symptoms such as flank pain and urinary tract infection but 11 were asym…

AdultMalemedicine.medical_specialtyVoiding cystourethrogramAdolescentUrologyUrinary systemKidneyUrologic Surgical ProcedureAsymptomaticDuplex KidneyYoung AdultUretermedicineHumansChildUpper urinary tractAgedRetrospective Studiesmedicine.diagnostic_testbusiness.industryInfant NewbornDisease ManagementInfantMiddle AgedSurgerymedicine.anatomical_structureTreatment OutcomeDuplex (building)Child PreschoolUrologic Surgical ProceduresFemaleKidney Diseasesmedicine.symptomUreterbusinessFollow-Up StudiesForecastingUreteral ObstructionThe Journal of urology
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Vocational training integrated into inpatient psychosomatic rehabilitation--short and long-term results from a controlled study.

2005

Purpose. The aim of this study was to determine the impact of a vocational training programme on short- and long-term results after psychosomatic rehabilitation. Method. 1,590 inpatients were screened for vocational integration. A high-risk group of 266 patients was randomly assigned to the vocational training programme plus psychosomatic treatment; treatment- as- usual served as a control condition. An occupational training was conducted at local companies, closely integrated into psychosomatic treatment. Vocational attitudes and adjustment were studied at intake, discharge, three, 12 and 24 month follow-ups. Results. More than half of the study participants were unemployment and/or long-t…

AdultMalemedicine.medical_specialtyWorkmedicine.medical_treatmentmedia_common.quotation_subjectlaw.inventionRandomized controlled triallawGermanymedicineHumansmedia_commonInpatientsRehabilitationWork disabilityRehabilitationRehabilitation VocationalLong term resultsPsychophysiologic DisordersOccupational trainingTreatment OutcomeWork (electrical)AttitudeVocational educationUnemploymentPhysical therapyFemalePsychologyFollow-Up StudiesDisability and rehabilitation
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A decision tree to help determine the best timing and antiretroviral strategy in HIV-infected patients.

2011

SUMMARYOptimal antiretroviral strategies for HIV-infected patients still need to be established. To this end a decision tree including different antiretroviral strategies that could be adopted for HIV-infected patients was built. A 10-year follow-up was simulated by using transitional probabilities estimated from a large cohort using a time-homogeneous Markov model. The desired outcome was for patients to maintain a CD4 cell count of >500 cells/mm3without experiencing AIDS or death. For patients with a baseline HIV viral load ⩾5 log10copies/ml, boosted protease inhibitor-based immediate highly active antiretroviral therapy (HAART) allowed them to spend 12% more time with CD4 ⩾500/mm3than…

AdultMalemedicine.medical_specialty[ INFO ] Computer Science [cs]EpidemiologyAnti-HIV AgentsDecision treeHIV InfectionsDrug Administration ScheduleCohort Studies03 medical and health sciences0302 clinical medicineLife ExpectancyAcquired immunodeficiency syndrome (AIDS)Internal medicineAntiretroviral Therapy Highly ActiveHiv infected patientsMedicineHumansProtease inhibitor (pharmacology)In patient[INFO]Computer Science [cs]Computer Simulation030212 general & internal medicineCd4 cell countComputingMilieux_MISCELLANEOUS0303 health sciences030306 microbiologybusiness.industryDecision TreesMiddle AgedViral Loadmedicine.diseaseAntiretroviral therapyMarkov Chains3. Good healthCD4 Lymphocyte CountInfectious DiseasesTreatment OutcomeImmunologyDisease ProgressionFemalebusinessViral loadFollow-Up StudiesEpidemiology and infection
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Long-term follow-up of a multifocal apodized diffractive intraocular lens after cataract surgery.

2007

Purpose To report the long-term performance of the AcrySof ReSTOR SA60D3 intraocular lens (IOL) after cataract surgery. Setting University Hospital Maastricht, Maastricht, The Netherlands. Methods This prospective clinical trial comprised 44 eyes (22 consecutive patients) having cataract surgery with implantation of the ReSTOR IOL. Monocular and binocular uncorrected distance visual acuity, best corrected distance visual acuity, uncorrected near visual acuity, best distance-corrected near visual acuity, spectacle dependence, undesired visual symptoms, patient satisfaction, and incidence of posterior capsule opacification were analyzed 6 months and 3 years postoperatively. Results The mean u…

AdultMalemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentEye diseaseAcrylic ResinsVisual AcuityIntraocular lensRefraction OcularCataractContrast SensitivityPatient satisfactionLens Implantation IntraocularOphthalmologySurveys and QuestionnairesmedicineHumansProspective StudiesProspective cohort studyAgedAged 80 and overLenses IntraocularVision BinocularPhacoemulsificationbusiness.industryGlare (vision)PhacoemulsificationCataract surgeryMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomePatient SatisfactionCapsulotomyQuality of LifeOptometrySurgeryFemalesense organsbusinessFollow-Up StudiesJournal of cataract and refractive surgery
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Myxoma of the orbit: a clinicopathologic report.

1990

A 27-year-old white man developed proptosis of his left eye over a period of 2 years. It was associated with vertical diplopia and displacement of the left globe down and laterally. Ultrasonography showed a cystic mass in the superior orbital region. Computed tomography (CT) demonstrated a solid, well-defined lesion behind the globe displacing the optic nerve medially. A transfrontal craniotomy revealed a nodular mass in the posterior and superior orbit, which extended anteriorly up to the globe. Histopathology, immunohistochemistry, and transmission electron microscopy proved the tumor to be a myxoma.

AdultMalemedicine.medical_specialtygenetic structuresmedicine.medical_treatmentEye diseaseLesionCellular and Molecular NeurosciencemedicineDiplopiaExophthalmosHumansCraniotomyUltrasonographyDiplopiabusiness.industryMyxomaAnatomymedicine.diseaseeye diseasesSensory SystemsOphthalmologymedicine.anatomical_structureOptic nerveOrbital NeoplasmsHistopathologysense organsmedicine.symptombusinessTomography X-Ray ComputedMyxomaOrbit (anatomy)Follow-Up StudiesGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
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Associations of disordered sleep with body fat distribution, physical activity and diet among overweight middle-aged men

2015

This cross-sectional study aimed to investigate whether body fat distribution, physical activity levels and dietary intakes are associated with insomnia and/or obstructive sleep apnea among overweight middle-aged men. Participants were 211 Finnish men aged 30-65 years. Among the 163 overweight or obese participants, 40 had insomnia only, 23 had obstructive sleep apnea only, 24 had comorbid insomnia and obstructive sleep apnea and 76 were without sleep disorder. The remaining 48 participants had normal weight without sleep disorder. Fat mass, levels of physical activity and diet were assessed by dual-energy X-ray densitometry, physical activity questionnaire and 3-day food diary, respectivel…

AdultMalemedicine.medical_specialtyinsomniaCognitive Neurosciencephysical activityComorbidityMotor ActivityOverweightBody Mass IndexOSABehavioral NeuroscienceFolic AcidSleep Initiation and Maintenance DisordersSurveys and QuestionnairesInternal medicinemedicineInsomniaBody Fat DistributionHumansObesityExerciseFinlandAdiposityAgedSleep Apnea ObstructiveSleep disorderbusiness.industrySleep apneaApneata3141dietary intakesFeeding BehaviorGeneral MedicineMiddle AgedOverweightmedicine.diseaseDietary FatsObesityDietObstructive sleep apneaCross-Sectional Studiesfat distributionObesity AbdominalPhysical therapymedicine.symptombusinessBody mass indexJournal of Sleep Research
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