Search results for "fol"
showing 10 items of 7082 documents
Development of a novel in vitro system for biomedical applications
2022
Nella ricerca scientifica e medica, l'uso degli animali ha apportato notevoli benefici all’uomo. Sebbene la loro fisiologia non imiti perfettamente il corpo umano, essi agiscono come perfetti "modelli" per lo studio delle malattie umane e lo sviluppo di nuovi farmaci e trattamenti. Tuttavia, secondo la Food and Drug Administration (FDA), solo l'8% dei farmaci testati sugli animali è considerato sicuro ed efficace per l'uso sull’essere umano, il 92% non lo è. Questi tassi di fallimento estremamente elevati nello sviluppo di farmaci, insieme ai costi in forte aumento, hanno portato molti ricercatori a rivalutare il valore degli studi in vivo sugli animali. Questo è stato il motivo per cui, ne…
3D numerical modeling of an anthropogenic sinkhole in the Marsala area of western Sicily
2013
SCAFFOLDS POLILATTIDICI PER APPLICAZIONI BIOMEDICHE
2010
PLLA scaffolds with controlled architecture as potential microenvironment for in vitro tumor model
2019
Abstract The "microenvironment" where a tumor develops plays a fundamental role in determining its progression, the onset of metastasis and, eventually, its resistance to therapies. Tumor cells can be considered more or less invasive depending both on the nature of the cells and on the site where they are located. Commonly adopted laboratory culture protocols for the investigation of tumor cells take usually place on standard two-dimensional supports. However, such cultures do not allow for reproduction of the biophysical properties of the tumor’s microenvironment, thus causing the cells to lose most of their relevant characteristics. In this work MDA-MB 231 breast cancer cells were cultiva…
"Anche Madama petrarcheggia?"
2010
Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29
2002
Abstract ERp29 is a soluble protein localized in the endoplasmic reticulum (ER) of eukaryotic cells, which is conserved in all mammalian species. The N-terminal domain of ERp29 displays sequence and structural similarity to the protein disulfide isomerase despite the lack of the characteristic double cysteine motif. Although the exact function of ERp29 is not yet known, it was hypothesized that it may facilitate folding and/or export of secretory proteins in/from the ER. ERp29 is induced by ER stress, i.e. accumulation of unfolded proteins in the ER. To gain an insight into the mechanisms regulating ERp29 expression we have cloned and characterized the rat ERp29 gene and studied in details …
"Table 7" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Unfolded Dijet conditional yields (Delta p_{T} > 3). Full markers represent p+Pb, open markers p+p
"Table 3" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Unfolded Dijet conditional yields. Full markers represent p+Pb, open markers p+p
"Table 5" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Ratio of unfolded Dijet conditional yields (P PB/ P P). Different colors correspond to different combinations of p_{T,1} and p_{T,2}
"Table 9" of "Dijet azimuthal correlations and conditional yields in $pp$ and $p$+Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV with the ATLAS dete…
2020
Ratio of unfolded Dijet conditional yields (P PB/ P P) (Delta p_{T} > 3). Different colors correspond to different combinations of p_{T,1} and p_{T,2}