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showing 10 items of 7082 documents

BMI and an anthropometry-based estimate of fat mass percentage are both valid discriminators of cardiometabolic risk: A comparison with DXA and bioim…

2013

Objective. To determine whether categories of obesity based on BMI and an anthropometry-based estimate of fat mass percentage (FM% equation) have similar discriminative ability for markers of cardiometabolic risk as measurements of FM% by dual-energy X-ray absorptiometry (DXA) or bioimpedance analysis (BIA).Design and Methods. A study of 40–79-year-old male (n=205) and female (n=388) Finns. Weight, height, blood pressure, triacylglycerols, HDL cholesterol, and fasting blood glucose were measured. Body composition was assessed by DXA and BIA and a FM%-equation.Results. For grade 1 hypertension, dyslipidaemia, and impaired fasting glucose >6.1 mmol/L, the categories of obesity as defined b…

AdultMalelcsh:Internal medicinemedicine.medical_specialtyArticle SubjectEndocrinology Diabetes and MetabolismBody Mass IndexBMIAbsorptiometry PhotonPredictive Value of Testscardiometabolic riskInternal medicinefat mass percentagebioimpedanceElectric ImpedancemedicineHumansObesitylcsh:RC31-1245AgedDXACardiometabolic riskNutrition and DieteticsAnthropometrybusiness.industryReproducibility of ResultsPublic Health Global Health Social Medicine and Epidemiologyta3141Middle AgedAnthropometryImpaired fasting glucosemedicine.diseaseObesityConfidence intervalNäringsläraFolkhälsovetenskap global hälsa socialmedicin och epidemiologiBlood pressureEndocrinologyAdipose TissueROC CurvePredictive value of testsBody CompositionCardiologyFemalebusinessBody mass indexResearch ArticleJournal of Obesity
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[Arterial hypertension and prediabetes].

2016

Abstract Background and objectives The aim of this study was to assess the factors related to new diabetes in hypertensive. Patients and methods This prospective follow-up study involved 2588 non-diabetic, hypertensive patients. The total follow-up was 15,053 patient-years with a median of 3.4 years (interquartile interval 1.4–6.8). Results During the follow-up, 333 (13%) patients had new diabetes, with a conversion rate of 2.21 (95% confidence interval [CI], 1.98–2.46) 100/patients/year. In a Cox proportional hazard model including baseline characteristics and modifications during the follow-up the three components of metabolic syndrome (excluding blood pressure and glucose values) HR 1.69…

AdultMalemedicine.medical_specialty030204 cardiovascular system & hematologyPrediabetic State03 medical and health sciences0302 clinical medicineInterquartile rangeRisk FactorsDiabetes mellitusInternal medicinemedicineHumans030212 general & internal medicinePrediabetesProspective StudiesFamily historyAgedProportional Hazards ModelsAged 80 and overbusiness.industryProportional hazards modelMiddle Agedmedicine.diseaseCombined Modality TherapyConfidence intervalPrimary PreventionEndocrinologyBlood pressureDiabetes Mellitus Type 2HypertensionFemaleMetabolic syndromebusinessFollow-Up StudiesMedicina clinica
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Subcutaneous interferon β-1a may protect against cognitive impairment in patients with relapsing-remitting multiple sclerosis: 5-year follow-up of th…

2013

ObjectiveTo assess the effects of subcutaneous (sc) interferon (IFN) -1a on cognition over 5 years in mildly disabled patients with relapsing-remitting multiple sclerosis (RRMS).MethodsPatients aged 18-50 years with RRMS (Expanded Disability Status Scale score ≤4.0) who had completed the 3-year COGIMUS study underwent standardized magnetic resonance imaging, neurological examination, and neuropsychological testing at years 4 and 5. Predictors of cognitive impairment at year 5 were identified using multivariate analysis.ResultsOf 331 patients who completed the 3-year COGIMUS study, 265 participated in the 2-year extension study, 201 of whom (75.8%; sc IFN β-1a three times weekly: 44 µg, n = …

AdultMalemedicine.medical_specialty5 year follow upMultiple SclerosisAdolescentScienceInjections SubcutaneousBrain damageYoung AdultInterferonRecurrenceInternal medicinemedicineHumansIn patientYoung adultCognitive impairmentSex CharacteristicsMultidisciplinarymedicine.diagnostic_testbusiness.industryMultiple sclerosisQRMultiple Sclerosis Subcutaneous interferon β-1a cognitive impairmentMagnetic resonance imagingInterferon-betamedicine.diseaseTreatment OutcomeImmunologyMedicineFemaleSettore MED/26 - Neurologiamedicine.symptomSafetybusinessCognition DisordersInterferon beta-1amedicine.drugResearch ArticleFollow-Up Studies
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Knee arthroscopy and exercise versus exercise only for chronic patellofemoral pain syndrome: 5-year follow-up.

2011

Objective To study the long-term outcome of arthroscopy in patients with chronic patellofemoral pain syndrome (PFPS), the authors conducted a randomised controlled trial. The authors also investigated factors predicting the outcome in patients with PFPS. Methods Fifty-six patients with PFPS were randomised into two groups: an arthroscopy group (N=28), treated with knee arthroscopy and an 8-week home exercise programme, and a control group (N=28), treated with a similar 8-week home exercise programme only. The primary outcome was the Kujala score on pain and function at 5-year. Secondary outcomes were visual analogue scales (VASs) to assess activity-related symptoms. Results According to the…

AdultMalemedicine.medical_specialty5 year follow upPhysical Therapy Sports Therapy and Rehabilitationlaw.inventionArthroscopyYoung AdultRandomized controlled triallawmedicineHumansOrthopedics and Sports MedicineIn patientYoung adultta315Knee arthroscopyIntention-to-treat analysismedicine.diagnostic_testbusiness.industryArthroscopyGeneral Medicinemedicine.diseaseCombined Modality TherapyExercise TherapyIntention to Treat AnalysisTreatment OutcomePatellofemoral Pain SyndromeChronic DiseasePhysical therapyFemalebusinessPatellofemoral pain syndromeFollow-Up StudiesBritish journal of sports medicine
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Unexplained Elevated Serum Pancreatic Enzymes: A Reason to Suspect Celiac Disease

2006

BACKGROUND & AIMS: The frequency of elevated serum pancreatic enzymes in patients with celiac disease (CD) is unknown. The aim of this study was to evaluate the serum levels of pancreatic enzymes in CD patients. METHODS: Serum pancreatic isoamylase and lipase levels were assayed in 90 adult and 112 pediatric consecutive CD patients at diagnosis and after 12 months of gluten-free diet (GFD). Serum elastase and trypsin levels were assayed in a subgroup of adult CD patients. Pancreatic ultrasonography was also performed. RESULTS: Twenty-six adult (29%) and 29 pediatric (26%) CD patients exhibited elevated values of serum pancreatic amylase and/or lipase; trypsin was elevated in 69% and elastas…

AdultMalemedicine.medical_specialtyAbdominal painSettore MED/09 - Medicina InternaPancreatic diseaseAdolescentGlutensAsymptomaticInternal medicineDiabetes mellitusGFD gluten-free dietmedicineHumansTrypsinAmylaseLipaseChildPancreatic ElastaseHepatologybiologybusiness.industryElastaseGastroenterologyCase-control studyLipasemedicine.diseasetTGs transglutaminasePancreatic celiacCeliac DiseaseEmA anti-endomysiumEndocrinologyCase-Control StudiesChild PreschoolCD celiac diseaseAmylasesbiology.proteinFemalemedicine.symptomSD standard deviationbusinessIsoamylaseFollow-Up StudiesClinical Gastroenterology and Hepatology
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Changes in accommodative responses with multifocal contact lenses: a pilot study.

2011

Our aim was to evaluate induced changes in pupil and accommodative response for different accommodative stimuli with three different multifocal contact lenses (CLs). Accommodative and pupil responses with three aspheric multifocal CLs of simultaneous focus center near (PureVision Low Add, PureVision High Add and Focus Progressives) for two accommodative stimuli of -2.5 and -4.00 D were recorded in 10 young subjects. Accommodative response, peak velocity, and time constant of accommodation and pupil constriction were assessed. The measurements were evaluated in all the participants with distance-single vision CLs and with the three multifocal CLs. The monocular measurements were performed in…

AdultMalemedicine.medical_specialtyAccommodative responsegenetic structuresContact LensesVisual AcuityPilot ProjectsRefraction OcularPupillaw.inventionOpticsCLs upper limitslawOphthalmologymedicineHumansMathematicsMonocularCross-Over Studiesbusiness.industryAccommodation OcularPupilPresbyopiaEquipment Designmedicine.diseaseRefractive Errorseye diseasesLens (optics)OphthalmologyTreatment OutcomePeak velocityOftalmologíaFemalebusinessAccommodationOptometryFollow-Up StudiesOptometry and vision science : official publication of the American Academy of Optometry
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Long-term functional results of digital replantation: A survey of 28 patients

2019

We sought to evaluate the long-term quality of life and functional outcome of patients who underwent digital replantation after amputation. A retrospective single-center study was conducted of patients treated between January 2010 to May 2016. Twenty-eight patients who underwent successful replantation after single or multiple digital amputation were reviewed in person after at least 2years' follow-up (mean 4.6years). Total active range of motion, grip and pinch strength were assessed. Functional outcomes were evaluated using the SF-36 and DASH questionnaires. The patients' occupational status and daily activities were reported. Mean total active range of motion was 42% of the contralateral…

AdultMalemedicine.medical_specialtyActivities of daily livingAdolescentmedicine.medical_treatment[SDV]Life Sciences [q-bio]030230 surgeryThumb03 medical and health sciencesGrip strengthDisability EvaluationYoung Adult0302 clinical medicineReturn to WorkQuality of lifeAmputation TraumaticDashFinger InjuriesmedicineHumansOrthopedics and Sports MedicineRange of Motion ArticularAgedRetrospective Studies030222 orthopedicsHand Strengthbusiness.industryRehabilitationMiddle AgedSurgerybody regionsCold Temperaturemedicine.anatomical_structureAmputationReplantationSensory ThresholdsReplantationQuality of LifeSurgeryFemaleRange of motionbusinessFollow-Up Studies
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Effects of a three-month active rehabilitation program on psychomotor performance of lower limbs in subjects with low back pain: a controlled study w…

1998

Proper psychomotor performance is needed in work and in activities of daily living, but among subjects with low back pain this area has been studied Little. The present purpose was to evaluate the effect and permanence of a 3-mo. physical exercise program on the psychomotor performance of lower limbs in subjects with low back pain. The associations between psychomotor performance and intensity of low back pain and subjective disability were also evaluated. 90 subjects with nonspecific, subacute low back pain were assigned to one of the three groups: one given three months intensive training, one home exercise, or the control group. Four measurement sessions were made during the 1-yr. study…

AdultMalemedicine.medical_specialtyActivities of daily livingmedicine.medical_treatmentMovementExperimental and Cognitive PsychologyPhysical exerciseSeverity of Illness Index050105 experimental psychology03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineBack painReaction TimeHumans0501 psychology and cognitive sciencesExercise physiologyExercisePain MeasurementPsychomotor learningLegRehabilitation05 social sciences030229 sport sciencesLow back painTrunkSensory SystemsExercise TherapySelf CareTreatment OutcomePhysical therapyFemalemedicine.symptomPsychologyLow Back PainPsychomotor PerformanceFollow-Up StudiesPerceptual and motor skills
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Analysis of the Blood Viscosity Behavior in the Sicilian Study on Juvenile Myocardial Infarction

2018

Considering the role of hemorheology in coronary circulation, we studied blood viscosity in patients with juvenile myocardial infarction. We examined whole blood viscosity at high shear rate using the cone-on-plate viscosimeter Wells-Brookfield ½ LVT and at low shear rate employing a viscometer Contraves LS30 in 120 patients (aged <46 years) with myocardial infarction, at the initial stage and subsequently 3 and 12 months after. At the initial stage, patients had an increased whole blood viscosity in comparison to normal controls. This hemorheological profile was not influenced by the cardiovascular risk factors, nor by the extent of coronary lesions, even if some differences were evide…

AdultMalemedicine.medical_specialtyAcute coronary syndromeBlood viscosityInfarction030204 cardiovascular system & hematologyFollow-Up Studie03 medical and health sciencesCoronary circulation0302 clinical medicineInternal medicinemedicineHumanscardiovascular diseases030212 general & internal medicineMyocardial infarctionAcute Coronary SyndromeNeutrophil to lymphocyte ratioblood rheologybusiness.industryOriginal ArticlesHematologyGeneral MedicineMiddle AgedBlood Viscositymedicine.diseasemedicine.anatomical_structureItalyHeart failureCardiologyST Elevation Myocardial InfarctionFemaleHemorheologyjuvenile myocardial infarctionbusinessFollow-Up StudiesHumanClinical and Applied Thrombosis/Hemostasis
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Improving the Course of Depressive Symptoms After Inpatient Psychotherapy Using Adjunct Web-Based Self-Help: Follow-Up Results of a Randomized Contro…

2019

Background We recently showed in a randomized controlled trial that Web-based self-help as an adjunct improved the effectiveness of multimodal inpatient psychotherapy for depression. Objective The aims of this study were (1) to determine whether a Web-based self-help adjunctive to multimodal inpatient psychotherapeutic treatment could also improve the course of depressive symptoms and (2) to identify predictors of residual depressive symptoms at follow-up. Methods Overall, 229 patients were randomized either to the Web-based self-help intervention group (Deprexis) or an active control group (Web-based information about depression and depressive symptoms) in addition to multimodal inpatient…

AdultMalemedicine.medical_specialtyAdolescent020205 medical informaticsMEDLINEPsychological interventionHealth Informatics02 engineering and technologylaw.inventionYoung Adult03 medical and health sciences0302 clinical medicineQuality of lifeRandomized controlled triallaw0202 electrical engineering electronic engineering information engineeringHumansMedicineDepression (differential diagnoses)AgedOriginal PaperInpatientsInternetDepressionbusiness.industrypsychology clinicalMiddle AgedCombined Modality TherapyMental health030227 psychiatryPsychotherapySelf-Help GroupsQuality of LifeNumber needed to treatPhysical therapyAnxietyFemalemedicine.symptombusinessmental healthaftercareFollow-Up StudiesJournal of Medical Internet Research
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