Search results for "forme"

Campaniformes et cultures locales en France méditerranéenne

2006

Since the 1998 Riva del Garda conference and the synthesis coordinated by J Guilaine (2001), the new bell beakers archaeological data of Mediterranean France make it possible to specify the relations between the Bell Beakers ones and indigenous populations of the final Neolithic in this area. The phase of synchrony between Bell Beakers and local cultures, highlighted for the Early Bell Beakers between 2500 and 2400 before our era, can undoubtedly be wide at the first times, at least, development of the regional groups of recent bell beakers ("Rhodano- Provençal" and "Pyrénéen"). In parallel, differences in relations between these Bell beakers and the indigenous populations can be supposed i…

Une nouvelle sépulture campaniforme à Hégenheim (F-Haut-Rhin), in : Jeunesse C. et Denaire A., dir.

2009

Decline in Coccolithophore Diversity and Impact on Coccolith Morphogenesis Along a Natural CO2 Gradient

2014

A natural pH gradient caused by marine CO2 seeps off Vulcano Island (Italy) was used to assess the effects of ocean acidification on coccolithophores, which are abundant planktonic unicellular calcifiers. Such seeps are used as natural laboratories to study the effects of ocean acidification on marine ecosystems, since they cause long-term changes in seawater carbonate chemistry and pH, exposing the organisms to elevated CO2 concentrations and therefore mimicking future scenarios. Previous work at CO2 seeps has focused exclusively on benthic organisms. Here we show progressive depletion of 27 coccolithophore species, in terms of cell concentrations and diversity, along a calcite saturation …

Subcellular distribution of ras in human and murine fibroblasts.

1996

Abstract Ras proteins play a significant role in signal transduction in response to growth factors and in cell transformation. To be active, ras has to be translocated to the cell membrane. Since subcellular distribution has been mainly studied in vector-transformed cells which highly express ras proteins, and it has been difficult to detect ras in cells expressing the protein at physiological levels, we studied subcellular distribution in human and murine fibroblasts. Here we show for the first time that a significant amount of ras is associated with the membrane skeleton and the cytoskeleton.

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme

2008

Abstract Purpose: Cancer stem cells (CSC) are thought to represent the population of tumorigenic cells responsible for tumor development. The stem cell antigen CD133 identifies such a tumorigenic population in a subset of glioblastoma patients. We conducted a prospective study to explore the prognostic potential of CSC analysis in glioblastoma patients. Experimental Design: We investigated the relationship between the in vitro growth potential of glioblastoma CSCs and patient death or disease progression in tumors of 44 consecutive glioblastoma patients treated with complete or partial tumorectomy followed by radiotherapy combined with temozolomide treatment. Moreover, we evaluated by immun…

P03.04 Signaling questions assessing brain tumor patients’ distress in clinical routine - a feasibility study

2019

Abstract BACKGROUND Approximately 20%-35% of patients with intracranial tumors show depressive symptoms and distress. Assessment in these patients remains challenging due to cognitive and/or neurological deficits. We developed 3 signaling questions in order to assess patients during patient-doctor consultation. The aim is to implement them in clinical routine and to compare the results with patient reported outcome measures (PROMs) along disease trajectory. MATERIAL AND METHODS Patients were prospectively examined in a structured interview applying the 3 following questions: 1),Has your mood worsened? (I)”; 2),Are you strained by physical changes? (II)”; 3),Has your faculty of thought decre…

Quantitative modeling of clinical, cellular, and extracellular matrix variables suggest prognostic indicators in cancer: a model in neuroblastoma

2014

BACKGROUND: Risk classification and treatment stratification for cancer patients is restricted by our incomplete picture of the complex and unknown interactions between the patient's organism and tumor tissues (transformed cells supported by tumor stroma). Moreover, all clinical factors and laboratory studies used to indicate treatment effectiveness and outcomes are by their nature a simplification of the biological system of cancer, and cannot yet incorporate all possible prognostic indicators. METHODS: A multiparametric analysis on 184 tumor cylinders was performed. To highlight the benefit of integrating digitized medical imaging into this field, we present the results of computational s…

Le mineur de 13 ans au seuil de la responsabilité pénale

2019

International audience

A bibliometric analysis of the literature on non-financial information reporting: Review of the research and network visualization

2022

[EN] This paper presents a bibliometric analysis of articles on the topic of non-financial information (NFI) reporting. The exponential growth over the last decade (90% of the articles were published in the last 10 years) indicates the relevance of the topic, but little is known about the structure and extent of research in this academic field. The purpose of this article is to provide a structured and up-to-date picture of the state of the art on the topic. We analyse the most relevant articles, authors, journals, countries and organizations. The analysis includes 3113 articles, collected from the Web of Science (WoS) Core Collection from 1970 —when the first two articles on the topic were…

LES VARIATIONS DU NIVEAU MARIN SUR LE BASSIN DE PARIS AU BATHONIEN-CALLOVIEN. IMPACTS SUR LES COMMUNAUTÉS BENTHIQUES ET SUR L'ÉVOLUTION DES ORNITHELL…

1992

The study deals with the biological impacts of sea-Ievel changes on evolution of a Jurassic benthic fossil group (Ornithellida, Brachiopoda). The different time and scale at which the shifts in marine environments occur leads to the recognition of three interacting dynamic systems: environmental, communities, populations dynamics. The analysis is thus divided into a three steps hierarchy: sequence stratigraphy, analysis of the diversity of brachiopod assemblages, and analysis of morphological variations within omithellid populations. Sequence stratigraphy of the Dogger marly and carbonate successions in the Paris basin provides accurate correlations of depositional environments from shallow…