Search results for "fragmentation"

Down-Regulation of Ku Autoantigen, DNA-Dependent Protein Kinase, and Poly(ADP-ribose) Polymerase during Cellular Senescence

1997

During aging and cellular senescence mutations accumulate in genomic and mitochondrial DNA. Ku autoantigens, DNA-dependent protein kinase, and poly (ADP-ribose) polymerase have an essential role in DNA damage recognition. Our purpose was to find out whether cellular senescence of fibroblasts affects the protein components that recognize DNA damage and induce the repair process. We compared presenescent and replicatively senescent human WI-38 fibroblasts with each other and with SV-40 immortalized and serum-deficient quiescent WI-38 cells. Our results showed that replicative senescence significantly decreased the nuclear level of both p70 and p86 components of Ku autoantigen. SV-40 immortali…

Functional Redundancy and Complementarities of Seed Dispersal by the Last Neotropical Megafrugivores

2013

Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:28:22Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:42:48Z : No. of bitstreams: 1 2-s2.0-84873586375.pdf: 1508075 bytes, checksum: 7e697f6c67a83195e9b0cb525355980e (MD5) Made available in DSpace on 2014-05-27T11:28:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-02-07 Background: Functional redundancy has been debated largely in ecology and conservation, yet we lack detailed empirical studies on the roles of functionally similar species in ecosystem function. Large bodied frugivores may disperse similar plant species and have strong impact on plant recruitment in tropical forests. Th…

Effects of work exposure to electromagnetic waves and organic compounds on sperm DNA fragmentation in patients undergoing ICSI

2011

Multiple stressors facilitate the spread of a non-indigenous bivalve in the Mediterranean Sea

2018

Aim The introduction of non‐indigenous species (NIS) via man‐made corridors connecting previously disparate oceanic regions is increasing globally. However, the environmental and anthropogenic factors facilitating invasion dynamics and their interactions are still largely unknown. This study compiles and inputs available data for the NIS bivalve Brachidontes pharaonis across the invaded biogeographic range in the Mediterranean basin into a species distribution model to predict future spread under a range of marine scenarios. Location Mediterranean Sea. Methods A systematic review produced the largest presence database ever assembled to inform the selection of biological, chemical and physic…

Geospatial modelling and map analysis allowed measuring regression of the upper limit of Posidonia oceanica seagrass meadows under human pressure

2018

Abstract Marine coastal ecosystems are facing structural and functional changes due to the increasing human footprint worldwide, and the assessment of their long-term changes becomes particularly challenging. Measures of change can be done by comparing the observed ecosystem status to a purposely defined reference condition. In this paper, a geospatial modelling approach based on 2D mapping and morphodynamic data was used to predict the natural position of the upper limit (i.e., the landward continuous front) of Posidonia oceanica seagrass meadows settled on soft bottom. This predictive model, formerly developed at the regional spatial scale, was here applied for the first time at the Medit…

Priority areas for the conservation of Atlantic forest large mammals

2009

Large mammal faunas in tropical forest landscapes are widely affected by habitat fragmentation and hunting, yet the environmental determinants of their patterns of abundance remain poorly understood at large spatial scales. We analysed population abundance and biomass of 31 species of medium to large-bodied mammal species at 38 Atlantic forest sites (including three islands, 26 forest fragments and six continuous forest sites) as related to forest type, level of hunting pressure and forest fragment size using ANCOVAs. We also derived a novel measure of mammal conservation importance for each site based on a "Mammalian Conservation Priority index" (MPi) which incorporates information on spec…

Shoreline Evolution and Environmental Changes at the NW Area of the Gulf of Gela (Sicily, Italy)

2021

Coastal areas are among the most biologically productive, dynamic and valued ecosystems on Earth. They are subject to changes that greatly vary in scale, time and duration and to additional pressures resulting from anthropogenic activities. The aim of this work was to investigate the shoreline evolution and the main environmental changes of the coastal stretch between the towns of Licata and Gela (in the Gulf of Gela, Sicily, Italy). The methodology used in this work included the analysis of: (i) shoreline changes over the long- and medium-term periods (1955–2019 and 1989–2019, respectively), (ii) dune system fragmentation and (iii) the impact of coastal structures (harbours and breakwaters…

Advanced fragmentation stage of oxide coating on polymer substrate under biaxial tension

2005

Crack patterns of 100-nm-thick silicon oxide coating on polypropylene film subjected to equibiaxial stress loading are studied experimentally. The loading is achieved by means of a bulging cell mounted under an optical microscope with stepwise pressurization of film specimens. The evolution of the coating fragment area distribution at relatively high strains is modeled using Weibull statistics to describe the coating strength. The fragment area distribution at an advanced fragmentation stage is shown to scale with the average fragment area, the latter being a power function of the applied biaxial strain.

Common Core in Danger? Personalized Information and the Fragmentation of the Public Agenda

2021

The diversification of information sources has reignited the controversy on media-induced fragmentation endangering social integration. The media's capability to set the public agenda and create issues as a common core is a pivotal part of the public sphere and contributes fundamentally to society's cohesion. Algorithm-driven sources like social media that personalize content to the preferences of individuals and their social networks are considered agents of fragmentation of the public sphere. Politically extreme individuals relying on them may be particularly vulnerable to losing touch with society's common core. We employ an innovative operationalization of fragmentation on the individu…

Structure, stability, and fragmentation of sodium bis(2-ethylhexyl)sulfosuccinate negatively charged aggregates in vacuo by MD simulations.

2014

Negatively charged supramolecular aggregates formed in vacuo by n bis(2-ethylhexyl)sulfosuccinate (AOT(-)) anions and n + n(c) sodium counterions (i.e., [AOT(n) Na(n+nc)](nc)) have been investigated by molecular dynamics (MD) simulations for n = 1 to 20 and n(c) = -1 to -5. By comparing the maximum excess charge values of negatively and positively charged AOTNa aggregates, it is found that the charge storage capability is higher for the latter systems, the difference decreasing as the aggregation number increases. Statistical analysis of physical properties like gyration radii and moment of inertia tensors of aggregates provides detailed information on their structural properties. Even for …