Search results for "functional"

Standing time and daily proportion of sedentary time are associated with pain-related disability in a one month accelerometer measurement in adults w…

2022

Abstract Objectives: The association between the subjective experience of pain-related disability (PRD) and device-measured physical activity (PA) and sedentary behavior (SB) in overweight and obese adults is not well known. The aim of this study was to investigate the associations of pain markers with accelerometer-measured SB duration and different intensities of PA among physically inactive middle-aged adults with overweight or obesity. Methods: This cross-sectional analysis included 72 subjects (27 men) with mean age of 57.9 (SD 6.7) years and mean BMI of 31.6 (SD 4.1) kg/m². SB and standing time (ST), breaks in sedentary time, light physical activity (LPA) and moderate-to-vigorous phys…

Methodological advances in the functional profiling of genomic studies

2013

In this thesis we present bioinformatic tools and algorithms for the analysis of genomic data such as those generated by microarray devices or next generation sequencing techniques. Particularly, we develop new approaches to gene set analysis. The described procedures should be useful in practice to tackle complex biological experiments, but hopefully will also be methodologically relevant, as they introduce new ways of conceptualizing genomic functional profiling. Our very flexible approach allows for the inclusion of not just one kind of genomic measurement but many. It makes possible, for instance, to analyze expression measurement and genomic variation data at a time. This multidimensio…

An Information Systems Design Product Theory for Software Project Estimation and Measurement Systems

2009

There is relatively little research on software Project Estimation and Measurement Systems (PEMS). Commercial PEMS vary in functionality and effectiveness. Their intended users thus do not know what to expect from PEMS and how to evaluate them. This paper creates an information system design product theory for the class of PEMS that prescribes the meta-requirements, the meta-design, and applicable theories for all products within the class. Meta-requirements and the meta-design are derived from the project estimation and measurement literature, experiences obtained during more than ten years of empirical work in Finnish Software Measurement Association, and a commercially available PEMS.

Effects of Functional Strength Training on Functional Movement and Balance in Middle-Aged Adults

2021

Functional movement deficiencies cause falls and injuries in adults. Functional strength training (FST) is emerging as a new training method for athletes, middle-aged and older adults, to improve functional movement: The present study was conducted in order to investigate the effects of FST on balance and functional movement in healthy and independent middle-aged adults. The sample for this study consisted of 46 physically active individuals (24 female and 22 male). A total of 46 subjects were divided based on randomly into the functional strength training (FST) group (n = 26) aged: 51.55 ± 3.73 years; height: 168.69 ± 8.8 cm; body mass: 75.88 ± 12.18; and traditional s…

Infografikas skolēnu funkcionālās rakstīšanas prasmju pilnveidei 5. klases angļu valodas stundās

2020

Angļu valoda ir nostiprinājusies kā pasaules starptautiskā valoda. Tomēr, lai gūtu panākumus visās ikdienas dzīves jomās, ir nepieciešams apgūt rakstisko komunikāciju, jeb funkcionālās rakstīšanas prasmes. Neskatoties uz to, ka skolēni skolas laikā tiek mācīti rakstīt, viņi bieži izprot funkcionālās rakstīšanas principus un likumus ar lielām grūtībām. Tāpēc diplomdarba mērķis bija izpētīt efektīvas mācīšanas pieejas, lai uzlabotu 5. klases skolēnu funkcionālās rakstīšanas prasmes ar pašu veidotu infografiku palīdzību. Izvēlētā pētījuma metode bija gadījuma izpēte, kura ietvēra vienu anketu skolēniem un skolēnu rakstiskos darbus kā datu vākšanas metodes. Tika noskaidrots, ka funkcionālās rak…

Radiation engineered nanogels as platforms for medical diagnostics and therapeutic nanodevices

2015

A scalable, single step, synthetic approach for the manufacture of biocompatible, functionalized microgels and nanogels has been developed. Pulsed EB irradiation of PVP aqueous solutions, at relatively low energies per pulse and doses within the sterilization dose range, has led to a variety of ‘as-born’ sterile, functional nanostructures that exhibit a combination of favourable properties which make them suitable as biomedical nanocarriers. Reactive functional groups have been generated by graft copolymerization of functional acrylic monomers. These groups can be used to attach fluorescent probes to the NPs, to bioconjugate ligands of specific cell receptors and to incorporate therapeutics…

Clay nanocomposites based on functionalized polyethylene. Effect of the clay modifier and the preparation conditions

2009

INTERACTIONS BETWEEN FUNCTIONALIZED THERMOPLASTIC ELASTOMER AND LAYERED DOUBLE HYDROXIDES

2016

Results coming from rheological analysis clearly suggest that in SEBS-g-MA-based nanocomposites, containing high amount of o-LDH, the formation of strong interactions between the dispersed nanoparticles and maleic functionalities of matrix occurs. A significant modification of the rheological behaviour can be noticed due to the formation of gel-like structures.

Physical disability in community-dwelling older people after hip fracture : randomized controlled trials with physical rehabilitation

2013

Evoked local field potentials can explain temporal variation in blood oxygenation level-dependent responses in rat somatosensory cortex

2010

The aim of this study was to explain the temporal variations between subjects in the blood oxygenation level-dependent (BOLD) response. Somatosensory responses were elicited with the electrical forepaw stimulus at a frequency of 10 Hz in urethane-anesthetized rats, and functional magnetic resonance imaging (fMRI) with BOLD contrast and local field potential (LFP) measurements were performed simultaneously. BOLD fMRI activation was evaluated by two different models, one based on the stimulus paradigm (the block model) and the other on the simultaneously measured evoked LFP responses. In the initial analysis, the LFP model captured the BOLD activation in the primary somatosensory cortex in al…