Search results for "functioning"

2020

Background: Physical activity (PA) of higher intensity and longer duration mainly accumulates from older adults' out-of-home activities. Outdoor PA is influenced by environmental features; however, the day-to-day variability of PA and its associations with environmental features have not been widely studied. This study focused on the associations of environmental features with accelerometer-measured PA in older people on weekdays and weekend days. Methods: The study population comprised 167 community-dwelling older people aged 75-90 years. Accelerometers were worn on 7 consecutive days and a structured interview on physical functioning, health, and socioeconomic factors was administered. A …

When people in close relationships are not prepared to listen to emotional disclosures

2007

The following article comprises a presentation of  research carried out on a group of 268 adults. The survey aimed at finding answers to questions posed about the meditative role played by social constraints in the relationship between shyness and certain aspects of emotional and social functioning. The results indicate that social constraints are a destructive factor in the everyday functioning of those facing everyday problems. Many shy people experience social constraints - people in close relationships: family, relatives, and friends react inadequately and negatively, demonstrating a lack of empathy, thus discouraging people who are shy from expressing their personal thoughts and emotio…

Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognition.

2014

ABSTRACT The Mycobacterium tuberculosis genome includes the large family of pe_pgrs genes, whose functions are unknown. Because of precedents in other pathogens in which gene families showing high sequence variation are involved in antigenic variation, a similar role has been proposed for the pe_pgrs genes. However, the impact of immune selection on pe_pgrs genes has not been examined. Here, we sequenced 27 pe_pgrs genes in 94 clinical strains from five phylogenetic lineages of the M. tuberculosis complex (MTBC). We found that pe_pgrs genes were overall more diverse than the remainder of the MTBC genome, but individual members of the family varied widely in their nucleotide diversity and in…

Funcionamiento diferencial del ítem de la evaluación internacional PISA. Detección y comprensión

2014

Este trabajo analiza el funcionamiento diferencial del ítem (FDI) de la prueba de comprensión lectora de la evaluación PISA2000 entre la muestras del Reino Unido y España. Se estudian los ítems liberados con el fin de aunar las fases de detección del FDI con la comprensión de sus causas. En la fase de detección se comparan los resultados de los procedimientos Mantel-Haenszel, Regresión Logística y Medias Estandarizadas en sus versiones para ítems dicotómicos y politómicos. Los resultados muestran que dos ítems presentan funcionamiento diferencial aunque el estudio post-hoc llevado a cabo sobre su contenido no ha podido precisar sus causas.

Neurobiological roots of language in primate audition : common computational properties

2015

Here, we present a new perspective on an old question: how does the neurobiology of human language relate to brain systems in nonhuman primates? We argue that higher-order language combinatorics, including sentence and discourse processing, can be situated in a unified, cross-species dorsal-ventral streams architecture for higher auditory processing, and that the functions of the dorsal and ventral streams in higher-order language processing can be grounded in their respective computational properties in primate audition. This view challenges an assumption, common in the cognitive sciences, that a nonhuman primate model forms an inherently inadequate basis for modeling higher-level language…

Frontiers of metal-coordinating drug design

2020

INTRODUCTION: The occurrence of metal ions in biomolecules is required to exert vital cellular functions. Metal-containing biomolecules can be modulated by small-molecule inhibitors targeting their metal-moiety. As well, the discovery of cisplatin ushered the rational discovery of metal-containing-drugs. The use of both drug types exploiting metal–ligand interactions is well established to treat distinct pathologies. Therefore, characterizing and leveraging metal-coordinating drugs is a pivotal, yet challenging, part of medicinal chemistry. AREA COVERED: Atomic-level simulations are increasingly employed to overcome the challenges met by traditional drug-discovery approaches and to compleme…

Parental Psychological Control, Quality of Family Context and Life Satisfaction Among Italian Adolescents

2012

The aim of the study was to explore the unique and common contributions of parental psychological control and family functioning to global life satisfaction among Italian adolescents while considering the type of parental psychological control: dependencyoriented and achievement-oriented. Two hundred fifty-five adolescents (104 boys and 151 girls) from 15 to 17 years of age (mean age = 15.98, SD = .76) completed self-report measures on perceived parental psychological control, dependency- and achievement-oriented, family functioning and global life satisfaction. Correlation analyses indicated that parental psychological control oriented to both dependency and achievement was negatively rela…

The Role of Individual and Relational Characteristics on Alcohol Consumption among Italian Adolescents: A Discriminant Function Analysis

2013

The aim of the present study was to explore the association between family functioning, coping strategies, peer influences and alcohol use among Italian adolescents. Nine hundred and sixty-three Italian adolescents, aged from 14 to 17 years, completed self-report measures assessing alcohol use, family functioning, and coping strategies. According to previous research, adolescents were categorized into non-drinkers, social, binge and heavy drinkers. Results showed that adolescents belonging to groups characterized by alcohol misuse differ in terms of coping strategies, family functioning dimensions, and typology of friends. In particular, heavy drinkers appeared to have more friends who drin…

Rasch Analysis of Authentic Evaluation of Young Children's Functioning in Classroom Routines.

2021

This study evaluated the functioning of children in early childhood education classroom routines, using the 3M Functioning in Preschool Routines Scale. A total of 366 children aged 36 to 70 months and 22 teachers from six early childhood education centers in Spain participated in the study. The authors used the Rasch model to determine the item fit and the difficulty of the items in relation to children's ability levels in this age range. The Rasch Differential Item Functioning (DIF) analysis by child age groups showed that the item difficulty differed according to the children's age and according to their levels of competence. The results of this study supported the reliability and validit…

Liberal and Conservative Differential Item Functioning Detection Using Mantel-Haenszel and SIBTEST: Implications for Type I and Type II Error Rates

2004

The aim of this work was to determine, in terms of Type I and Type II error rates, the risks of applying various statistical procedures for evaluating differential item functioning. To this end, the authors carried out a simulation study in which the Mantel-Haenszel and SIBTEST procedures were applied in conjunction. The variables manipulated were sample size and distribution of ability between groups. Results indicated that, although there was a high rate of agreement between the procedures, the joint Type I and Type II error rate may vary substantially from that obtained when each of the procedures was applied separately. Furthermore, the authors analyzed empirical data to obtain informat…