Search results for "fusion"
showing 10 items of 4513 documents
Preclinical Effect of Absorption Modifying Excipients on Rat Intestinal Transport of Model Compounds and the Mucosal Barrier Marker 51Cr-EDTA
2017
There is a renewed interest from the pharmaceutical field to develop oral formulations of compounds, such as peptides, oligonucleotides, and polar drugs. However, these often suffer from insufficient absorption across the intestinal mucosal barrier. One approach to circumvent this problem is the use of absorption modifying excipient(s) (AME). This study determined the absorption enhancing effect of four AMEs (sodium dodecyl sulfate, caprate, chitosan, N-acetylcysteine) on five model compounds in a rat jejunal perfusion model. The aim was to correlate the model compound absorption to the blood-to-lumen clearance of the mucosal marker for barrier integrity, 51Cr-EDTA. Sodium dodecyl sulfate a…
A Multisensor Proposal for Wireless Sensor Networks
2008
Every sensor node in a wireless sensor network (WSN) has a microcontroller, a transmitter/receiver and a sensor. It is able to acquire data from specific point in a real environment and transmit it through the WSN. Sometimes it is useful to gather different type of data from the same place in order to obtain a final result. In the related literature, very few works are about sensing different parameters using a unique sensor. In this paper we propose a Wireless IP multisensor that is able to gather several types of data from the environment and transmit the result of their combination. Our proposal decision has being mainly based on its development costs, its expansion capacity and its flex…
Small solid renal masses: Characterization by diffusion-weighted MRI at 3 T
2013
AIM: To describe the appearance of small solid renal lesions (≤3 cm) on diffusion-weighted magnetic resonance imaging (MRI) and to determine whether ADC measurements may help to differentiate benign from malignant small solid renal masses. METHODS AND MATERIALS: Thirty-five patients with 47 small renal masses (23 malignant, 24 benign) who underwent 3 T MRI of the kidney using diffusion-weighted sequences (b values of 0 and 1000 s/mm(2)) were retrospectively evaluated. Qualitative and quantitative analysis of diffusion-weighted images was performed. RESULTS: Most lesions were hyperintense to kidney on high b-value diffusion-weighted images and hypointense on apparent diffusion coefficient (A…
Regional hypothermia of the kidney: surface or transarterial perfusion cooling? A functional study.
1980
Hypothermia reduces ischemic damage if prolonged occlusion of the renal artery is required during an in situ kidney operation. Hypothermia may be achieved by external cooling or by transarterial hypothermic perfusion. External cooling may lower intrarenal temperature heterogeneously. Perfusion techniques via intra-arterial catheters introduced percutaneously are associated with minimal technical difficulties. The 95 patients who underwent extensive hypothermic nephrolithotomy had differential 131iodine hippuran clearance studies preoperatively, and 2 weeks and 6 to 46 months postoperatively. Sixty-three kidneys were cooled by transarterial hypothermic perfusion and 39 were cooled with topic…
Study of the retention and release of n-hexanal incorporated into soy protein isolate–lipid composite films
2010
[EN] This work deals with the study of the kinetic of aroma release, which had been previously incorporated into soy protein isolate (SPI)-lipid composite films. The aim was to determine the influence of type and amount of lipidic material on aroma (n-hexanal) release and retention, as well as the apparent diffusion coefficients. To carry out this study it have been employed SPI-based films containing two SPI:LIPID ratios (1:0.25 and 1:0.5), and two types of lipids, oleic acid (OA) and beeswax (BW), in OA:BW ratios 100:0, 70:30, 50:50, 30:70 and 0:100. The measurements were performed by a gas chromatography technique. The films that showed more retention were SPI:LIPID 1:0.5 100% BW and con…
On the Kneser property for reaction–diffusion systems on unbounded domains
2009
Abstract We prove the Kneser property (i.e. the connectedness and compactness of the attainability set at any time) for reaction–diffusion systems on unbounded domains in which we do not know whether the property of uniqueness of the Cauchy problem holds or not. Using this property we obtain that the global attractor of such systems is connected. Finally, these results are applied to the complex Ginzburg–Landau equation.
Population targeted requirements acquisition
2018
ABSTRACTWe use social science theories, design science research methodology, and our experience in five development projects to design principles for selecting or adapting requirements acquisition (RA) techniques for use with populations of customers and users. The information systems (IS) literature has not systematically focused on the adaption of RA techniques to particular populations. We developed a nascent design theory for RA to target specific populations to define functional requirements for new IS. Five reference theories – personal construct theory, theory of disability, diffusion of innovations, social actor theory, and media richness and information synchronicity theory – suppo…
Levels of Adoption in Organizational Implementation of E-Collaboration Technologies
2008
While the e-collaboration term only dates back a few years, its roots can be traced back at least two decades to the research and development in areas such as groupware, computer supported cooperative work (CSCW), group support systems (GSS), and computer-mediated communication (CMC). As defined by Kock (2005), the e-collaboration term can be seen to encompass a wide range of technologies supporting collaboration among indivduals engaged in a common task. In this article, the e-collaboration term thus incorporates previous research and practice within the areas mentioned above. The term organizational implementation is used to denote the process of introducing the technology in an organizat…
Digital innovations in rural micro-enterprises
2020
Digitalization gives micro-enterprises and rural areas new possibilities and it can support their competitiveness. In this paper, we have presented one way of supporting the diffusion and adoption of digital innovations in rural micro-enterprises. First, we examined the challenges and digital competence of the micro-enterprises in the rural areas of Central Finland to better understand what they needed. The second step was to develop a workshop concept. Theories of innovation diffusion and adoption were used as a base for these workshops. The last step was to evaluate the developed concept, its effects and challenges. We found that the workshop concept worked well for spreading information,…
Study of Toner Penetration in Papers by Laser Induced Plasma Spectroscopy and Optical Profilometry
2023
Four major toners are used in the printing industry, cyan, magenta, yellow and black (Key) for making color images on paper. Paper brands suitable for printing have thin mineral/latex coatings, and toners are applied on top of the coating in the printing process. Chemical compositions from toner to toner, as well as from coating to coating, vary according to the needs of the end user. Interactions between the toner and the coating define the final color formation of the images in printing. Hence, it is important to study characteristics and dynamics of toners on coated papers. In this paper, we have used laser-induced plasma spectroscopy (LIBS) to provide information on elemental distributi…