Search results for "fusion"

A generalized Degn–Harrison reaction–diffusion system: Asymptotic stability and non-existence results

2021

Abstract In this paper we study the Degn–Harrison system with a generalized reaction term. Once proved the global existence and boundedness of a unique solution, we address the asymptotic behavior of the system. The conditions for the global asymptotic stability of the steady state solution are derived using the appropriate techniques based on the eigen-analysis, the Poincare–Bendixson theorem and the direct Lyapunov method. Numerical simulations are also shown to corroborate the asymptotic stability predictions. Moreover, we determine the constraints on the size of the reactor and the diffusion coefficient such that the system does not admit non-constant positive steady state solutions.

Highly protective alkalinization by ammonia vapor diffusion in viscosimetric DNA damage assessment.

1988

A method for the measurement of viscosities correlated to DNA alterations in alkaline homogenate suspensions is described. The alkaline pH shift to afford cell lysis, DNA unfolding, and denaturation is attained by gaseous ammonia diffusion, thus avoiding shear stress from mechanical mixing. At the same time a stabilizing density gradient is established. This solution is run through a plastic measuring tube that is wide enough to minimize the influence of uneven swelling of the lysing DNA-containing components. Flow times under a carefully controlled water head are registered, and their ratios to control solutions are evaluated. The relative viscosities show a strong and irreversible depende…

A chimera carrying the functional domain of the orphan protein SLC7A14 in the backbone of SLC7A2 mediates trans-stimulated arginine transport.

2012

In human skin fibroblasts, a lysosomal transport system specific for cationic amino acids has been described and named system c. We asked if SLC7A14 (solute carrier family 7 member A14), an orphan protein assigned to the SLC7 subfamily of cationic amino acid transporters (CATs) due to sequence homology, may represent system c. Fusion proteins between SLC7A14 and enhanced GFP localized to intracellular vesicles, co-staining with the lysosomal marker LysoTracker(®). To perform transport studies, we first tried to redirect SLC7A14 to the plasma membrane (by mutating putative lysosomal targeting motifs) but without success. We then created a chimera carrying the backbone of human (h) CAT-2 and …

p42 MAPK phosphorylates 80 kDa MARCKS at Ser-113.

1996

Abstract It is demonstrated here that p42 MAPKinase (p42 MAPK) phosphorylates the M yristoylated A lanine- R ich C - K inase S ubstrate (MARCKS) at Ser-113. In permeabilised Swiss 3T3 cells activation of protein kinase C (PKC) leads to p42 MAPK activation, but only the protein kinase C sites in MARCKS become phosphorylated and not Ser-113. The mitogen platelet-derived growth factor (PDGF) elicits the same response. These results demonstrate that while Ser-113 is a substrate for p42 MAPK in vitro and can be phosphorylated in vivo as shown by Taniguchi et al. [(1994) J. Biol. Chem. 269, 18299–18302], its phosphorylation is not subject to acute regulation by p42 MAPK in Swiss 3T3 cells.

Characterization of a medium size Xe/TMA TPC instrumented with microbulk Micromegas, using low-energy gamma-rays

2014

NEXT-MM is a general-purpose high pressure (10 bar, $\sim25$ l active volume) Xenon-based TPC, read out in charge mode with an 8 cm $\times$8 cm-segmented 700 cm$^2$ plane (1152 ch) of the latest microbulk-Micromegas technology. It has been recently commissioned at University of Zaragoza as part of the R&D of the NEXT $0\nu\beta\beta$ experiment, although the experiment's first stage is currently being built based on a SiPM/PMT-readout concept relying on electroluminescence. Around 2 million events were collected during the last months, stemming from the low energy $\gamma$-rays emitted by a $^{241}$Am source when interacting with the Xenon gas ($\epsilon$ = 26, 30, 59.5 keV). The localized…

In situobservation of the generation and annealing kinetics of E ′ centres induced in amorphous SiO2by 4.7 eV laser irradiation

2011

The kinetics of E' centers induced in silica by 4.7eV laser irradiation was investigated observing in situ their optical absorption band at 5.8 eV. After exposure the defects decay due to reaction with diffusing molecular hydrogen of radiolytic origin. Hydrogen-related annealing is active also during exposure and competes with the photo-induced generation of the centers until a saturation is reached. The concentrations of E' and H2 at saturation are proportional, so indicating that the UV-induced generation processes of the two species are correlated. These results are consistent with a model in which E' and hydrogen are generated from a common precursor Si-H.

Transfusion sanguine. Responsabilité

1996

International audience; (Riom 6 avr. 1995, JCP 1995.4.325)

Swarming : An Investigation Practice Supporting a Bottom-up Ecological Transition

2022

Dans cet article, nous rendons compte des pratiques d’essaimage d’initiatives locales de transition portées par des collectifs citoyens et associatifs en région Bourgogne Franche-Comté. L’essaimage, défini comme une façon d’enquêter pour agir, caractérise un « activisme environnemental du faire » qui se structure de manière réticulaire et translocale. Ces multiples initiatives qui font des gestes du quotidien un levier de transformation écologique s’activent avec ou sans les institutions territoriales. Celles-ci, indépendamment de l’écho qu’elles renvoient à ces expérimentations, sont interpellées dans leur manière de concevoir l’action publique sous contrainte écologique forte.

L'ESSENZIALE NELL'IMAGING RM DI DIFFUSIONE, COLLO

2011

Whole-Body MRI and 18F-FDG-PET-CT for Lymphoma Staging: Comparison of Patient Experience

2015

Aims and objectives Methods and materials Results Conclusion Personal information References