Search results for "fusion"
showing 10 items of 4513 documents
The tumor-agnostic treatment for patients with solid tumors: a position paper on behalf of the AIOM- SIAPEC/IAP-SIBioC-SIF Italian Scientific Societi…
2021
The personalized medicine is in a rapidly evolving scenario. The identification of actionable mutations is revolutionizing the therapeutic landscape of tumors. The morphological and histological tumor features are enriched by the extensive genomic profiling, and the first tumor-agnostic drugs have been approved regardless of tumor histology, guided by predictive and druggable genetic alterations. This new paradigm of "mutational oncology", presents a great potential to change the oncologic therapeutic scenario, but also some critical aspects need to be underlined. A process governance is mandatory to ensure the genomic testing accuracy and homogeneity, the economic sustainability, and the r…
What happened to body-to-body sociability?
2013
This article aims to investigate how the body-to-body forms of sociability evolved from 1996 to 2009 simultaneously with the proliferation of ICTs in Europe and why this happened. The article also aims to find out how the socio-demographic profile of Europeans practising these forms developed in the same period of time. The analysis is based on two surveys carried out in Italy, France, the United Kingdom, Germany and Spain in 1996 (N = 6609) and 2009 (N = 7255). Results show that although the internal diffusion and frequency of the forms of communicative sociability changed, on the whole the amount of sociability has increased so slightly that it would be more appropriate to speak about rea…
Can ‘Openness-to-change’ and ‘Conservation’ Values Predict the Diffusion of the Internet into European Homes?
2019
Abstract This study investigated whether openness-to-change values (self-direction and stimulation) and conservation values (security and tradition) could predict the diffusion of the internet into homes by 2014, at the level of 159 European regions. All four value scales were correlated with the diffusion of the internet, after controlling for regional wealth and population density. Self-direction was by far the most consistent predictor of the diffusion of internet connections; a combination of self-direction and stimulation values could predict home internet use better than other combinations of human values. A longitudinal analysis, at the level of 25 countries, investigated the possibi…
Modelling of electromagnetic heating and mixing conditions in glass melt output equipment
2011
PurposeThe purpose of this paper is to investigate the outlet of a special glass melting system, which is used to control melt flow and modify flow pattern.Design/methodology/approachNumerical calculations in ANSYS and ANSYS CFX were used to study electromagnetic, thermal, hydrodynamic and chemical mixing processes, results are validated by comparison with experimental data.FindingsObtained results show that investigated approach can improve glass melt chemical homogeneity significantly – Lorentz force driven melt movement in conjunction with diffusion process ensures good mixing quality.Research limitations/implicationsThe mixing in glass melt is present only in azimuthal direction (in cyl…
A halocin acting on Na+/H+ exchanger of Haloarchaea as a new type of inhibitor in NHE of mammals
2006
10 páginas, 3 figuras.
Mechanisms for Translocation of Heavy Metals from Soil to Epigeal Mosses
2011
The mechanisms for translocation of heavy metals from soil to epigeal mosses were investigated. The first mechanism was demonstrated for (137)Cs and involved the uplifting of the pollutant-containing dust from the soil, followed by the local secondary deposition on surfaces of epigeal mosses and epiphytic lichens. The second mechanism involved the diffusion of metal cations from the soil through water wetting the moss into the gametophyte. The mechanism was demonstrated by measuring the electric conductance of wetted gametophytes with single ends immersed in solutions of Cu and Na salts. In addition, the concentrations of Cu and Cd were compared in moss samples exposed to the natural soil a…
Continental degassing of helium in an active tectonic setting (northern Italy): the role of seismicity
2020
AbstractIn order to investigate the variability of helium degassing in continental regions, its release from rocks and emission into the atmosphere, here we studied the degassing of volatiles in a seismically active region of northern Italy (MwMAX = 6) at the Nirano-Regnano mud volcanic system. The emitted gases in the study area are CH4–dominated and it is the carrier for helium (He) transfer through the crust. Carbon and He isotopes unequivocally indicate that crustal-derived fluids dominate these systems. An high-resolution 3-dimensional reconstruction of the gas reservoirs feeding the observed gas emissions at the surface permits to estimate the amount of He stored in the natural reserv…
Die thermische diffusion von polystyrol in verschiedenen lösungsmitteln
1969
Es wird uber Messungen von thermischen Diffusionskoeffizienten und LUDWIG-SORET-Koeffizienten von Polystyrol in den Losungsmitteln Toluol, Methylathylketon, Butylacetat und Cyclohexan berichtet. Es zeigte sich, das der rein thermisch bedingte Diffusionsprozes in Butylacetat und im Θ-Losungsmittel Cyclohexan unabhangig vom Molekulargewicht ist, wie as fur Toluol bereits fruher nachgewiesen werden konnte. Fur Methylathylketon wurde eine schwache, aber deutliche Abhangigkeit von D' vom Molekulargewicht zu D' ∼ M−0,12 gefunden. Bemerkenswerterweise verhalten sich die beiden in Bezug auf Polystyrol thermodynamisch sehr ahnlichen Losungsmittel Butylacetat und Methylathylketon in dieser Hinsicht s…
Response of cybrids and a somatic hybrid of lemon to Phoma tracheiphila infections
2000
The reaction of lemon hybrids obtained by symmetrical and asymmetrical protoplast fusion, toward “mal secco” infection caused by Phoma tracheiphila (Petri) Kanc. et Ghik. was examined. Resistance was tested in `Valencia' sweet orange [Citrus sinensis (L.) Osbeck] and `Femminello' lemon [C. limon (L.) Burm. f.] somatic hybrid and cybrids, by stem and leaf inoculation tests and by analysis of propagule number of P. tracheiphila in the xylem of stem-inoculated plants. In general, the somatic hybrid and the cybrids showed an intermediate degree of resistance, with slight differences in disease symptoms, in comparison with resistant `Monachello' lemon and susceptible `Femminello' lemon, used as …
Role of Wood Macromolecules on Selective Sorption of Phenolic Compounds by Wood
2008
Wood is a complex structure of various macromolecules, mainly cellulose, hemicellulose, and lignin. Although the sorption process of some organic compounds by wood has been elucidated, the relative contribution of its different fractions in the sorption mechanism is not clearly determined. Certain works predict the amount of organic compounds sorbed on wood as a direct relationship to its lignin fraction. All wood macromolecules, however, seem to have the capacity to sorb organic compounds. Sorption of phenolic compounds on individual wood macromolecules has been studied and compared to that on wood. Wood-water partition coefficients ( K wood) for phenolic volatiles and their sorption rates…