Search results for "fusion"

showing 10 items of 4513 documents

Trastuzumab-emtansine induced pleural and pericardial effusions

2021

Introduction Trastuzumab emtansine (T-DM1) is an antibody-drug conjugate which combine trastuzumab (T), a monoclonal antibody targeting the human epidermal growth factor receptor-2 (HER2), and a cytotoxic molecule derived from maytansine (DM1). Case report We report the first case of T-DM1-associated pleural and pericardial effusions three weeks after the second course of T-DM1 in a patient with breast cancer. Drug-induced pleural and pericardial effusions was implicated in the absence of other etiologies. The Naranjo Scale indicated a probable drug-induced adverse reaction. Management & outcome: The patient fully recovered after thoracentesis and discontinuation of T-DM1. The patient h…

musculoskeletal diseasesReceptor ErbB-2medicine.drug_classBreast NeoplasmsAdo-Trastuzumab EmtansineAntibodies Monoclonal HumanizedMonoclonal antibodyPericardial effusionPericardial Effusion03 medical and health scienceschemistry.chemical_compound0302 clinical medicineTrastuzumabmedicineHumansMaytansinePharmacology (medical)business.industryHuman epidermal growth factorTrastuzumabmedicine.diseaseOncologychemistryTrastuzumab emtansine030220 oncology & carcinogenesisCancer researchFemalebusiness030215 immunologymedicine.drugConjugateJournal of Oncology Pharmacy Practice
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Stellenwert der MR-Tomographie bei akuten Schulterluxationen

1992

24 patients up to two weeks after primary traumatic shoulder dislocation were examined at 0.5 and 1.5 T. Surgical and/or arthroscopic correlation was available in 13, CT-arthrographic correlation in 16 patients. A joint effusion allowing sufficient evaluation of the capsulolabral complex was present in 21/24 (87.5%) cases. 11/14 patients with combined dislocated detachments of the glenoid labrum and capsular lesions were subsequently operated upon. Marrow edema of the humeral head was found in 16/19 Hill-Sachs lesions and in 4/5 fractures of the greater tuberosity. Two patients presented with a lesion of the long biceps tendon associated with rotator cuff tears and were also subsequently op…

musculoskeletal diseasesmedicine.medical_specialtyGlenoid labrumbusiness.industryJoint effusionSurgeryLesionmedicine.anatomical_structureEdemamedicineTearsRadiology Nuclear Medicine and imagingShoulder jointRotator cuffmedicine.symptombusinessGreater TuberosityRöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Clinical and economic impact of infliximab one-hour infusion protocol in patients with inflammatory bowel diseases: A multicenter study

2017

AIM To assess the impact of short infliximab (IFX) infusion on hospital resource utilization and costs. METHODS All inflammatory bowel diseases (IBD) patients who received IFX 1 h infusion from March 2007 to September 2014 in eight centers from Southern Italy were included in the analysis. Demographic, clinical and infusion related data were collected. The potential benefits related to the short infusion protocol were assessed both in terms of time saving and increased infusion unit capacity. In addition, indirect patient-related cost savings were evaluated. RESULTS One hundred and twenty-five patients were recruited (64 with ulcerative colitis and 61 with Crohn’s disease). Median duration …

musculoskeletal diseasesmedicine.medical_specialtyObservational StudyCost savings03 medical and health sciences0302 clinical medicineInternal medicinemedicineIn patient030212 general & internal medicineEconomic impact analysisskin and connective tissue diseasesProtocol (science)business.industryInflammatory Bowel DiseasesOne-hour infusionInfliximabInfliximabMulticenter studyCost savingsstomatognathic diseasesEconomic impactMulticenter studyPhysical therapy030211 gastroenterology & hepatologybusinessmedicine.drugWorld Journal of Gastrointestinal Pharmacology and Therapeutics
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Bestimmung der Knochenqualität vor Wirbelsäuleninstrumentation - Stellenwert verschiedener in vivo-Methoden

2008

OBJECTIVE: The present investigation should elucidate which assessment technique for bone quality is most appropriate to estimate preoperatively fixation strength of instrumental spine fusions. METHODS: VDS-screw fixation strength in 50 human cadaveric vertebral bodies was approximated by means of pullout force assessment. Bone quality was assessed by Dual Energy X-ray Absorptiometry (DEXA), Quantitative Computed Tomography (QCT), MRT and histomorphometry. For each of these techniques, correlation with axial pull out force strength was investigated. RESULTS: Highest correlation was found for cancellous bone density (QCT) (r = 0.72; p < 0.001) and DEXA (r = 0.70; p < 0.001). MRT, cortical bo…

musculoskeletal diseasesmedicine.medical_specialtymedicine.diagnostic_testBone densitybusiness.industrymedicine.medical_treatmentmusculoskeletal systemSurgerymedicine.anatomical_structureSpinal fusionmedicineOrthopedics and Sports MedicineSurgeryCortical boneQuantitative computed tomographyNuclear medicinebusinessCadaveric spasmCancellous boneDual-energy X-ray absorptiometryFixation (histology)Zeitschrift für Orthopädie und ihre Grenzgebiete
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Solar neutrino spectroscopy in Borexino

2018

International audience; In more than ten years of operation, Borexino has performed a precision measurement of the solar neutrino spectrum, resolving almost all spectral components originating from the proton-proton fusion chain. The presentation will review the results recently released for the second data taking phase 2012–2016 during which the detector excelled by its unprecedentedly low background levels. New results on the rate of pp, 7Be, pep and 8B neutrinos as well as their implications for solar neutrino oscillations and metallicity are discussed.

neutrino: solarPhysics::Instrumentation and DetectorsSolar neutrinoMetallicityNuclear physicsbackground: lowneutrino: spectrum[PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex]Neutrino oscillationSpectroscopyBorexinoPhysicsProton–proton chain reactionpp-chainp p: fusionprecision measurementDetector* Automatic Keywords *13. Climate actionsolar neutrinosspectralHigh Energy Physics::ExperimentBorexinoneutrino: oscillationNeutrino[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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Joint local quantization and linear cooperation in spectrum sensing for cognitive radio networks

2014

—In designing cognitive radio networks (CRNs), protecting the license holders from harmful interference while maintaining acceptable quality-of-service (QoS) levels for the secondary users is a challenge effectively mitigated by cooperative spectrum sensing schemes. In this paper, cooperative spectrum sensing in CRNs is studied as a three-phase process composed of local sensing, reporting, and decision/data fusion. Then, a significant tradeoff in designing the reporting phase, i.e., the effect of the number of bits used in local sensing quantization on the overall sensing performance is identified and formulated. In addition, a novel approach is proposed to jointly optimize the linear soft-…

non-ideal reporting channelcognitive radio (CR)quantizationdecision fusioncooperative spectrum sensing
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La classificació de la documentació parlamentària de les Corts Valencianes: la funció de control al Consell.

2008

El dinamisme necessari en una institució parlamentària com les Corts Valencianes requereix de l'organització del fons documental i, per tant, la necessitat d'elaborar un sistema de gestió documental integral. L'objectiu és facilitar la recuperació d'informació parlamentària per a la millora de la gestió, la presa de decisions, l'enriquiment dels debats i la investigació sobre la institució. L'accés a la documentació facilita també el coneixement de les funcions de la cambra, i l'aproximació dels ciutadans a les Corts. Això s'ha concretat en l'elaboració d'un quadre de classificació per a descriure el fons documental i gestionar-ne la recuperació, l'eliminació o la conservació. La metodologi…

noneJE. Record keeping.Facultat de Medicina i OdontologiaBG. Information dissemination and diffusion.02DL. Archives.
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Częstość wykonywania zabiegu transfuzji uzupełniającej u noworodków donoszonych i przedwcześnie urodzonych w latach 2012–2016 na podstawie analizy do…

2018

Wprowadzenie. Transfuzja krwi jest częstym zabiegiem u noworodków. Osoba podejmująca decyzję o jego przeprowadzeniu musi być świadoma, że ratuje on życie i jest obciążony wieloma powikłaniami. Cel pracy. Określenie częstości wykonywania transfuzji uzupełniających u noworodków leczonych na Od-dziale Anestezjologii i Intensywnej Terapii Dzieci i Noworodków (OAITDiN) w Uniwersyteckim Szpitalu Klinicznym w Opolu latach 2012–2016. Ustalenie, czy istnieje istotna zależność między wiekiem noworodka a liczbą transfuzji. Zidentyfikowanie najczęstszych wskazań do przeprowadzenia transfuzji. Materiał i metody. Przeprowadzono analizę retrospektywną dokumentacji medycznej techniką nowoczesną polegającą …

noworodkiprzetaczanie krwinewbornblood transfusionneonatal intensive care unitoddział intensywnej opieki nad noworodkiemPielęgniarstwo i Zdrowie Publiczne
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Penning-trap mass measurements on 92, 94-98, 100Mo with JYFLTRAP

2012

Penning-trap measurements on stable 92, 94-98, 100Mo isotopes have been performed with relative accuracy of \ensuremath1⋅10−8\ensuremath1⋅10−8 with the JYFLTRAP Penning-trap mass spectrometer by using 85Rb as a reference. The Mo isotopes have been found to be about 3keV more bound than given in the Atomic Mass Evaluation 2003 (AME03). The results confirm that the discrepancy between the ISOLTRAP and JYFLTRAP data for 101-105Cd isotopes was due to an erroneous value in the AME03 for 96Mo used as a reference at JYFLTRAP. The measured frequency ratios of Mo isotopes have been used to update mass-excess values of 30 neutron-deficient nuclides measured at JYFLTRAP. peerReviewed

nuclear spectroscopyPhysicsNuclear and High Energy PhysicsMass excessIsotopeaccelerator-based physicsPenning trapMass spectrometrykiihdytinpohjainen fysiikkaISOLTRAPAtomic massNuclear physicsydinrakennenuclear structureydinspektroskopiaNuclear fusionNuclideAtomic physicsydinfysiikkaThe European Physical Journal A
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Mass measurements of neutron-deficient nuclei and their implications for astrophysics

2012

During the years 2005-2010 the double-Penning-trap mass spectrometer JYFLTRAP has been used to measure the masses of 90 ground and 8 isomeric states of neutron-deficient nuclides with a typical precision of better than 10keV. The masses of 14 nuclides -- 84Zr , 88, 89Tc , 90-92Ru , 92-94Rh , 94, 95Pd , 106, 108, 110Sb -- have been experimentally determined for the first time. This article gives an overview on these measurements and their impact on the modeling of the astrophysical rp -process. peerReviewed

nuclear spectroscopyPhysicsNuclear and High Energy PhysicsMass excessaccelerator-based physicsHadronMeasure (physics)Mass spectrometrykiihdytinpohjainen fysiikkaMass measurementNuclear physicsydinrakennenuclear structureydinspektroskopiaNuclear fusionNeutronNuclideydinfysiikkaThe European Physical Journal A
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