Search results for "fusion"
showing 10 items of 4513 documents
Optimization of the enzyme power source for a nano drug delivery system fuelled by glucose in blood plasma
2019
A unique in vivo electrical pulse generator to improve membrane permeability for drugs and simultaneously facilitate self-powered nano devices for nano drug delivery systems (NDDS) was identified. The use of an unsupported biological catalyst component of the power supply was aimed at the NDDS instead of a conventional membrane electrode assembly (MEA). Self-powered carriers of drugs and prodrugs with improved controlled release capability to target areas using substrate available in biological matrices such as glucose in blood is envisaged. The experimental application implemented prototype designed chambers allowing the entry of premixed precursors and low ohm resistance due the absence o…
Experimental Introgression To Evaluate the Impact of Sex Specific Traits on Drosophila melanogaster Incipient Speciation
2019
AbstractSex specific traits are involved in speciation but it is difficult to determine whether their variation initiates or reinforces sexual isolation. In some insects, speciation depends of the rapid change of expression in desaturase genes coding for sex pheromones. Two closely related desaturase genes are involved in Drosophila melanogaster pheromonal communication: desat1 affects both the production and the reception of sex pheromones while desat2 is involved in their production in flies of Zimbabwe populations. There is a strong asymmetric sexual isolation between Zimbabwe populations and all other “Cosmopolitan” populations: Zimbabwe females rarely copulate with Cosmopolitan males w…
In vivoanalysis of the lumenal binding protein (BiP) reveals multiple functions of its ATPase domain
2007
International audience; The endoplasmic reticulum (ER) chaperone binding protein (BiP) binds exposed hydrophobic regions of misfolded proteins. Cycles of ATP hydrolysis and nucleotide exchange on the ATPase domain were shown to regulate the function of the ligand-binding domain in vitro. Here we show that ATPase mutants of BiP with defective ATP-hydrolysis (T46G) or ATP-binding (G235D) caused permanent association with a model ligand, but also interfered with the production of secretory, but not cytosolic, proteins in vivo. Furthermore, the negative effect of BiP(T46G) on secretory protein synthesis was rescued by increased levels of wild-type BiP, whereas the G235D mutation was dominant. U…
Electrochemical polymerization of ambipolar carbonyl-functionalized indenofluorene with memristive properties
2019
Abstract Carbonyl-functionalized indenofluorene was electropolymerized with a high faradaic efficiency of 85% and the solid state properties of the resulting polymeric thin films were investigated. They displayed modular optical properties depending on their oxidation state. The approach used for inorganic semiconductors was applied to polyindeonofluorene derivative. Mott-Schottky analysis evidenced a switching from p-type to n-type electrical conduction, suggesting an ambipolar behaviour of the polymer. As an application, flexible organic memristors were fabricated and resistive switching properties were observed.
On Some Misconceptions Concerning Digital Banking and Alternative Delivery Channels
2016
A great deal of conceptual confusion surrounds the notions of digital banking and innovative alternative delivery channels that support banking and other financial transactions globally. The authors contend that the concepts of digital banking and associated delivery channels are ambiguous and restrictive; their usability has been undermined and their purpose and objective have, to a large extent, been misunderstood. Against this backdrop, the authors offer an inclusive definition of digital banking and delivery channels and provide logical explanations of these terms that can benefit scholars, the telecommunication sector, the banking industry, policy makers, and service providers (in term…
Cost-Effective eHealth System Based on a Multi-Sensor System-on-Chip Platform and Data Fusion in Cloud for Sport Activity Monitoring
2018
eHealth systems provide medical support to users and contribute to the development of mobile and quality health care. They also provide results on the prevention and follow-up of diseases by monitoring health-status indicators and methodical data gathering in patients. Telematic management of health services by means of the Internet of Things provides immediate support and it is cheaper than conventional physical presence methods. Currently, wireless communications and sensor networks allow a person or group to be monitored remotely. The aim of this paper is to develop and assess a system for monitoring physiological parameters to be applied in different scenarios, such as health or sports.…
Integrated GNSS/IMU Hub Motion Estimator for Offshore Wind Turbine Blade Installation
2019
Abstract Offshore wind turbines (OWTs) have become increasingly popular for their ability to harvest clean offshore wind energy. Bottom-fixed foundations are the most used foundation type. Because of its large diameter, the foundation is sensitive to wave loads. For typical manually assisted blade-mating operations, the decision to perform the mating operation is based on the relative distance and velocity between the blade root center and the hub, and in accordance with the weather window. Hence, monitoring the hub real-time position and velocity is necessary, whether the blade installation is conducted manually or automatically. In this study, we design a hub motion estimation algorithm f…
Ship-to-Ship State Observer Using Sensor Fusion and the Extended Kalman Filter
2019
In this paper, a solution for estimating the relative position and orientation between two ships in six degrees-of-freedom (6DOF) using sensor fusion and an extended Kalman filter (EKF) approach is presented. Two different sensor types, based on time-of-flight and inertial measurement principles, were combined to create a reliable and redundant estimate of the relative motion between the ships. An accurate and reliable relative motion estimate is expected to be a key enabler for future ship-to-ship operations, such as autonomous load transfer and handling. The proposed sensor fusion algorithm was tested with real sensors (two motion reference units (MRS) and a laser tracker) and an experime…
An adaptive multi-rate system for visual tracking in augmented reality applications
2016
The visual tracking of an object is a well-known problem, and it involves many fields of applications. Often a single sensor, the camera, could not provide enough information in order to track the whole object trajectory due to a low updating rate; therefore a multi-sensor system, based also on inertial measurements, could be necessary to improve the tracking accuracy. This leads to the fundamental question: how can information from different sensors be combined when they work at different rates? In this paper an approach based on recursive parameter estimation focusing on multi-rate situations is suggested. The problem is here formulated as the state-of-the-art problem of the visual tracki…
Friction Stir Welding of Ti6Al4V complex geometries for aeronautical applications: a feasibility study
2020
Abstract While Friction Stir Welding (FSW) of aluminium alloys can be considered a mature technology, even for complex joint morphologies, as T joints welded “in transparency”, welding of hard material still presents several open issues. In fact, welding of titanium alloys is a challenging process due to the chemical, mechanical and thermal characteristics of such materials which are subjected to atmosphere contamination resulting in joint hydrogen, oxygen and nitrogen embrittlement; additionally, due to the high melting temperature, large distortion and residual stress are found in joints obtained by traditional fusion welding processes as gas metal arc welding, electron beam welding and l…