Search results for "fusion"

Gold Nanorods as Plasmonic Sensors for Particle Diffusion.

2016

Plasmonic gold nanoparticles are normally used as sensor to detect analytes permanently bound to their surface. If the interaction between the analyte and the nanosensor surface is negligible, it only diffuses through the sensor’s sensing volume, causing a small temporal shift of the plasmon resonance position. By using a very sensitive and fast detection scheme, we are able to detect these small fluctuations in the plasmon resonance. With the help of a theoretical model consistent with our detection geometry, we determine the analyte’s diffusion coefficient. The method is verified by observing the trends upon changing diffusor size and medium viscosity, and the diffusion coefficients obtai…

Two-Dimensional Indium Selenide for Sulphur Vapour Sensing Applications

2020

Surface-to-volume ratio in two-dimensional (2D) materials highlights among their characteristics as an inherent and intrinsic advantage taking into account their strong sensitivity to surface effects. For this reason, we have proposed in this work micromechanically exfoliated 2D nanosheets of InSe as an optical vapour sensor. As a proof of concept, we used 2-mercaptoethanol as the chemical analyte in vapour phase to monitor the change of the InSe photoluminescence (PL) before and after exposure to the analyte. For short vapour exposure times (at low analyte concentration), we found a PL enhancement of InSe nanosheets attributed to the surface localization of Se defects. For long vapour expo…

Characterization of porous alumina membranes for efficient, real-time, flow through biosensing

2015

Abstract Nanofluidic sensing devices promise high performance by overcoming issues of mass transport of analyte molecules to the sensing surface, whilst micro-porous membranes promise high sensitivity due to a large surface for their capture. Anodic alumina (AAO) filter membranes allow the flow through of samples, and could be used as a convenient and readily available fluidic platform for the targeted delivering of analytes to bioreceptors immobilized on the pore walls. The relatively small pore dimensions, compared to fluidic diffusion lengths, promise highly efficient capture of analytes from the whole sample volume, enabling relatively fast sensing response times and the use of small sa…

Electrochemical pH Control at Gold Nanowires

2018

In this work, interdigitated arrays of nanowire electrodes are used with one array acting as the working electrode while the other is used to generate the required protons. Finite element simulations of the pH control electrodes were performed to provide insight on the generation and subsequent diffusion of protons. This informed the inter-tine spacing of the electrodes used.. This electrochemical pH control method was then used to enable the detection of analytes of interest.

Application of a Novel Refinement Method for Accurate Determination of Chemical Diffusion Coefficients in Electroactive Materials by Potential Step T…

2005

We describe application of a novel refinement method for an accurate determination of the chemical diffusion coefficient, D, and the generalized kinetic parameter, A, from experimental potentiostatic intermittent titration technique (PITT) data suited for a variety of electrochemically doped electroactive polymers and inorganic intercalation host materials. The proposed, simple, two-step refinement procedure, based on earlier derived analytical expressions for the PITT response, is exemplified by the analysis of chronoamperometric responses to small-amplitude potential perturbation for p- and n-doped poly(fluorenone-bithiophene) (PFDOBT-HH) thin film electrode. The initial p-doping and the …

Application of C1-Esterase Inhibitor During Reperfusion of Ischemic Myocardium

2001

Background—Complement activation during reperfusion of ischemic myocardium augments myocardial injury, and complement inhibition with C1-esterase inhibitor (C1-INH) at the time of reperfusion exerts marked cardioprotective effects in experimental studies. Application of C1-INH in newborns, however, was recently reported to have dangerous and even lethal side effects. This study addresses the essential role of dosage in studies using C1-INH.Methods and Results—Cardioprotection by C1-INH was examined in a pig model with 60 minutes of coronary occlusion followed by 120 minutes of reperfusion. C1-INH was administered intravenously 5 to 10 minutes before coronary reperfusion without heparin at a…

Three-dimensional architecture of the whole human soleus muscle

2018

Background Most data on the architecture of the human soleus muscle have been obtained from cadaveric dissection or two-dimensional ultrasound imaging. We present the first comprehensive, quantitative study on the three-dimensional anatomy of the human soleus muscle in vivo using diffusion tensor imaging (DTI) techniques. Methods We report three-dimensional fascicle lengths, pennation angles, fascicle curvatures, physiological cross-sectional areas and volumes in four compartments of the soleus at ankle joint angles of 69 ± 12° (plantarflexion, short muscle length; average ± SD across subjects) and 108 ± 7° (dorsiflexion, long muscle length) of six healthy young adults. Microdissection and …

Anesthetic management of a patient diagnosed with CADASIL (cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopat…

2011

CADASIL (cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leu-koencephalopathy) is an infrequent inherited disease that could have anesthetic implica-tions. However these have rarely been reported. We present a male patient previously diagnosed with CADASIL, who had suffered an ischemic vascular cerebral accident with a MRI compatible with leukoencephalopathy, and who was dependent for daily activities, and sustained dementia, mood alterations, apathy, and urine incontinence. He had famil-ial antecedents of psychiatric symptoms and ischemic stroke events in several relatives including his father, two brothers and one sister. He was scheduled for arthrodesis of the le…

Massively bleeding trauma patient: intervene but not too late

2022

Detection of mitochondrial electron chain carrier redox status by transhepatic light intensity during rat liver reperfusion.

2003

The aim of the study was to investigate mitochondrial electron transfer during rat liver reperfusion after cold storage and hypothermic machine perfusion. Livers from male Brown Norway rats were preserved (UW) for 10h either by cold storage (CS) or by hypothermic oxygenated perfusion extracorporal (HOPE). Transhepatic photometric analysis allowed determination of the redox status of mitochondrial cytochromes during preservation, rewarming and reperfusion. Mitochondrial electron chain carriers were inhibited at different sites with rotenone and cyanide in some experiments. reversed transcriptional polymerase chain reaction (RT-PCR) was performed after reperfusion concerning transcription of …