Search results for "g factor"
showing 10 items of 514 documents
Antecedents and Outcomes of Absorptive Capacity : Three Studies in the Spanish Manufacturing Sector
2013
En los últimos años, las investigaciones en dirección estratégica han señalado al conocimiento como uno de los recursos claves que permiten la generación de ventajas competitivas. No obstante, para la creación y mantenimiento de dichas ventajas es necesario el desarrollo de capacidades que permitan la transferencia y uso eficiente de dicho conocimiento, incluso en condiciones marcadas por la agitación y el dinamismo del entorno. En este marco, la capacidad de absorción ha sido destacada como una de las capacidades esenciales que proporciona a las organizaciones la habilidad de asimilar, transformar y explotar con éxito el conocimiento externo. No obstante, a pesar de las constantes contribu…
Decadal oscillations of the aquatic chemistry of river waters in Latvia
2018
Abstract. Water quality changes of surface waters can be used to assess human impact intensity, but of importance is to consider also impacts of climate change/variability and naturally occurring changes of environmental quality. In Latvia, during the recent decades a major reduction of anthropogenic pressure has happened due to restructuring of economy and industrial production, resulting in major decrease of loading of many groups of pollutants. However, trends and driving factors for other groups of substances have not been much studied. Long term (1980–2012) results of hydrochemical monitoring, performed in rivers of Latvia, are analysed during this study in connection with long-term se…
Long-term abundance dynamics of coastal zooplankton in the Gulf of Riga
1998
The dynamics of three most abundant mesozooplankton species in the coastal zone of the Gulf of Riga — Bosmina longispina, Synchaeta baltica, Keratella quadrata — is analyzed to detect the regulating environmental factors. The only significant downward trend of species abundance was found for S. baltica in autumn. Statistically significant correlation was estimated only between the summer salinity and the abundance of B. longispina. K. quadrata though showed a negative correlation with summer salinity. The abundance of S. baltica had only nonsignificant correlations with the environmental factors. The abundance of coastal mesozooplankton species is determined by the combination of hydrologic…
RUNX3 and T-Bet in Immunopathogenesis of Ankylosing Spondylitis—Novel Targets for Therapy?
2019
Susceptibility to ankylosing spondylitis (AS) is polygenic with more than 100 genes identified to date. These include HLA-B27 and the aminopeptidases (ERAP1, ERAP2, and LNPEPS), which are involved in antigen processing and presentation to T-cells, and several genes (IL23R, IL6R, STAT3, JAK2, IL1R1/2, IL12B, and IL7R) involved in IL23 driven pathways of inflammation. AS is also strongly associated with polymorphisms in two transcription factors, RUNX3 and T-bet (encoded by TBX21), which are important in T-cell development and function. The influence of these genes on the pathogenesis of AS and their potential for identifying drug targets is discussed here.
Carbon emissions by Ssouth american companies: driving factors for reporting decisions and emissions reduction
2018
In the last decade, companies have started to disclose information on carbon emissions. To our knowledge, this is the first paper to look into this phenomenon in South America, which is a very important geographical area regarding climate change because of the local nature and developing economies. This paper explores the relationships between some corporate variables and two important decisions: (i) whether to report carbon emissions, and (ii) the impact on the evolution of carbon emissions. Logit and linear panel data models are used to determine the driving factors for decisions (i) and (ii). Our results show that regarding the carbon reporting decision, a company&rsquo
A novel improved matlab-based software for the electric and magnetic analysis and design of rotating electrical machines
2015
The aim of this paper is to present a software for the analysis and design of windings of rotating electrical machines, considering both the electric and the magnetic specifications on the machine. The considered machines are induction motors (IM) and PM synchronous motors (PMSM). The software accounts for the case of buried magnets (IPMSM), but with some limits, because the calculations require a much more detailed analysis regarding the magnetic circuit. However, this initial limitation of the software, that will be removed in a later version, does not constitute a major limitation as confirmed by the examples presented in this paper.
Masennuksen pariterapian vaikuttavuuden erot tutkimusyksiköiden välillä ja niitä välittävät tekijät
2013
Tutkimuksen tarkoituksena oli selvittää masennuksen pariterapian vaikuttavuuden eroja tutkimusyksiköiden välillä ja niitä välittäviä tekijöitä. Näitä tavoitteita varten tutkittiin myös, onko pariterapia vaikuttavaa masennuksen hoidossa. Tutkimusyksiköiden välisiä eroja pariterapian tuloksellisuudessa on tutkittu vain vähän. Lisäksi tekijöitä, jotka välittävät tutkimusyksiköiden välisiä eroja masennuksen pariterapian tuloksellisuudessa ei ole ilmeisesti tutkittu. Kuitenkin masennuksen pariterapian tuloksellisuutta on tutkittu ja sen on todettu olevan tuloksellista (Kung, 2000). Tässä tutkimuksessa tarkasteltiin Länsi-Pohjan ja Pohjois-Savon tutkimusyksiköiden välisiä eroja masennuksen hoidon…
The Evolution of Hemophilia Care: Clinical and Laboratory Advances, Opportunities, and Challenges
2020
AbstractHemophilia A (HA) and B (HB) are X-linked bleeding disorders caused by mutations in the F8 or F9 gene that result in the absence, or reduced activity, of the corresponding clotting factor. The severity of bleeding and related complications is proportional to the amount of residual circulating functional factor. The development of a safe and effective hemophilia treatment lasted several decades and has been mainly based on clotting factor replacement. Advances in the engineering and manufacturing of clotting concentrates have led to the widespread availability of extended half-life products that reduced the number of intravenous infusions needed to achieve adequate trough levels. The…
Supportive care of the older cancer patient
2003
Aging is associated with decreased functional reserve of multiple organ systems and with changes in the pharmacokinetics and pharmacodinamics of drugs. Older individuals express enhanced susceptibility to the complications of cytotoxic chemotherapy, especially to myleotoxicity, mucositis, cardiotoxicity and neurotoxicity. The management of older individuals with chemotherapy involves then prevention of these complications. General precautions include proper patient selection, based on the comprehensive geriatric assessment (CGA), dose adjustment for agents that are renally excreted to the patient creatinine clearance and maintenance of hemoglobin levelsor =12 g/dl. Filgrastim and pegfilgras…
Infectious complications in patients with myelodysplastic syndromes: A review of the literature with emphasis on patients treated with 5-azacitidine.
2017
Myelodysplastic Syndromes are oligo-clonal stem cell disorders that are associated with cytopenias in the peripheral blood. Major causes for morbidity and mortality in myelodysplastic syndromes (MDS) patients are infections mostly due to bacteria or fungi. Beside leucopenia per se in affected patients, function of white blood cells particularly that of neutrophils seems to be impaired. Here we summarize the available data on infections in MDS patients in general and particularly those treated with 5-azacitidine.