Search results for "g(1)"
showing 7 items of 717 documents
Geography of urban and locational conflicts in Valencia and its metropolitan area
2021
Aquest article fa una anàlisi sobre els conflictes territorials sorgits al llarg dels darrers anys, de principis de la dècada de 2000 fins a 2013, a l’àrea metropolitana de València. Amb aquesta anàlisi, volem realitzar una radiografia sobre la conflictivitat territorial d’aquest espai urbà i avançar hipòtesis amb referència a les causes que la van provocar, com també estudiar les connexions espacials que es van establir, de cara a una formulació posterior de recomanacions per a una planificació urbana i territorial i un govern de la ciutat millors. Aquest treball és el resultat d’una recerca sistemàtica sobre conflictes territorials, actors i estratègies en tota mena de disputes relacionad…
Early Health, Risk Aversion and Stock Market Participation
2019
To examine the relationship between early health status and financial decisions in adulthood, we link information on birth weight in 1966 from the Northern Finland Birth Cohort to data from the Finnish Central Securities Depository over the period of 19952010. We find that persons predisposed to poor health status in early childhood (indicated by low birth weight) avoid participating in the stock market in adulthood. The link between birth weight and stock market participation is partially explained by the fact that poor early health status leads to risk aversion. Early health status is not significantly related to the portfolio’s value-growth tilt. nonPeerReviewed
Rab33B and its autophagic Atg5/12/16L1 effector assist in hepatitis B virus naked capsid formation and release
2015
Hepatitis B virus morphogenesis is accompanied by the production and release of non-enveloped capsids/nucleocapsids. Capsid particles are formed inside the cell cytosol by multimerization of core protein subunits and ultimately exported in an uncommon coatless state. Here, we investigated potential roles of Rab GTPases in capsid formation and trafficking by using RNA interference and overexpression studies. Naked capsid release does not require functions of the endosome-associated Rab5, Rab7 and Rab27 proteins, but depends on functional Rab33B, a GTPase participating in autophagosome formation via interaction with the Atg5-Atg12/Atg16L1 complex. During capsid formation, Rab33B acts in conju…
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
Assembly and Translocation of Papillomavirus Capsid Proteins
2002
ABSTRACT The major and minor capsid proteins of polyomavirus are preassembled in the cytoplasm and translocated to the nucleus only as a VP1-VP2/VP3 complex. In this study, we describe independent nuclear translocation of the L1 major protein and the L2 minor capsid protein of human papillomavirus type 33 by several approaches. First, we observed that expression and nuclear translocation of L2 in natural lesions precede expression of L1. Second, using a cell culture system for coexpression, we found that accumulation of L2 in nuclear domain 10 (ND10) subnuclear structures precedes L1 by several hours. In contrast, complexes of L2 and mutants of L1 forced to assemble in the cytoplasm are tra…
Volatility risk premia and financial connectedness
2014
In this paper we use the Diebold Yilmaz (2009 and 2012) methodology to construct an index of connectedness among five European stock markets: France, Germany, UK, Switzerland and the Netherlands, by using volatility risk premia. The volatility risk premium, which is a proxy of risk aversion, is measured by the difference between the implied volatility and expected realized volatility of the stock market for next month. While Diebold and Yilmaz focus is on the forecast error variance decomposition of stock returns or range based volatilities employing a stationary VAR in levels, we account for the (locally) long memory stationary properties of the levels of volatility risk premia series. The…
Les types de temps associés aux risques d’inondations et d’érosions en Camargue : éléments de diagnostic et de prospectives pour le 21e siècle (1993-…
2010
Les fortes surcotes marines et les fortes vagues sont les principaux aléas météo-marins associés aux risques de submersion et d’érosion du littoral camarguais. Sur la période 1993-2002, une forte fréquence mensuelle de très hautes surcotes marégraphiques est généralement associée à une forte fréquence de très hautes vagues. Ces deux phénomènes locaux se produisent principalement lorsqu'une dépression autour du Golfe de Gascogne est associée à des hautes pressions sur l’Europe Centrale. La fréquence mensuelle de ce type de temps nous renseigne sur la probabilité d’occurrence de fortes surcotes marégraphiques et vagues en Camargue. Au 21e siècle, la fréquence du type de temps associé aux plus…