Search results for "gea"

showing 10 items of 1040 documents

Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the int…

2019

ObjectivesDuring a ‘cannot intubate, cannot oxygenate’ situation, asphyxia can lead to cardiac arrest. In this stressful situation, two complex algorithms facilitate decision-making to save a patient’s life: difficult airway management and cardiopulmonary resuscitation. However, the extent to which competition between the two algorithms causes conflicts in the execution of pivotal treatment remains unknown. Due to the rare incidence of this situation and the very low feasibility of such an evaluation in clinical reality, we decided to perform a randomised crossover simulation research study. We propose that even experienced healthcare providers delay cricothyrotomy, a lifesaving approach, d…

AdultMale1682medicine.medical_treatmentCrossoverClinical Decision-MakingCardiopulmonary Resuscitation [E02.365.647.110]Simulated patientAnaesthesia03 medical and health sciences0302 clinical medicineManikins [J01.897.280.500.545.129.400]medicineHumansCricothyrotomy030212 general & internal medicineCardiopulmonary resuscitation1506Airway ManagementOriginal ResearchAsphyxiaCross-Over Studiesbusiness.industryAirway Management [E02.041]Patient SelectionGeneral MedicineUniversity hospitalCrossover studyCardiopulmonary ResuscitationAnesthesiology [H02.403.066]Heart ArrestHigh Fidelity Simulation Training[MeSH Tree numbers]: SimulationFemalemedicine.symptomLaryngeal MusclesbusinessAlgorithmHealthcare providers030217 neurology & neurosurgeryAlgorithmsBMJ Open
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Laparoscopic treatment for esophageal achalasia: experience at a single center

2013

Background. Achalasia is a not frequent esophageal disorder cha- racterized by the absence of esophageal peristalsis and incomplete re- laxation of the lower esophageal sphincter (LES). Its cause is unknown. The aim of treatment is to improve the symptoms. We report the results of the treatment of this condition achieved in one center. Patients and methods. We conducted a retrospective study of pa- tients with esophageal achalasia. In the period 2010-2012 we observed 64 patients, of whom 19 were referred for medical treatment. Three of Introduction Achalasia is a not frequent esophageal motor disor- der that affects both the body of the esophagus and the lower esophageal sphincter (LES). It…

AdultMaleAdolescentMiddle AgedClinical PracticeEsophageal AchalasiaSettore MED/18 - Chirurgia GeneraleYoung Adultlaparoscopy - Heller myotomy - intraoperative manometryHumansFemaleLaparoscopyAgedRetrospective Studies
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Dental and periodontal lesions in patients with gastro-oesophageal reflux disease.

2003

Dental erosion has been considered an extraesophageal manifestation of gastro-oesophageal reflux disease, but few reports have studied the relationship between this disease and other periodontal or dental lesions. The aim of this study was to investigate the prevalence of dental and periodontal lesions in patients with gastro-oesophageal reflux disease.A total of 253 subjects were prospectively studied between April 1998 and May 2000. Two study groups were established: 181 patients with gastro-oesophageal reflux disease and 72 healthy volunteers. Clinical assessment, including body mass index and consumption of tobacco and alcohol, was performed in all subjects, as well as a dental and peri…

AdultMaleAdolescentPeriodontal examinationDentistryDiseaseDental CariesSurveys and QuestionnairesPrevalenceMedicineHumansGingival RecessionTooth ErosionProspective StudiesProspective cohort studyGingival recessionAgedHepatologybusiness.industrydigestive oral and skin physiologyDental Plaque IndexGastroenterologyRefluxCase-control studyAge FactorsMiddle Ageddigestive system diseasesDental Plaque IndexLogistic ModelsSpainCase-Control StudiesGastroesophageal RefluxFemalemedicine.symptomPeriodontal IndexbusinessBody mass indexDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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In-vivo investigation of material quality of bone tissue by measuring apparent phalangeal ultrasound transmission velocity

1995

The square of ultrasound transmission velocity in a material is related to the modulus of elasticity, which is known to be an indicator of stability in bone. The aim of our study was to use ultrasound transmission velocity to obtain information about the material properties of bone tissue, keeping other factors possibly influencing ultrasound transmission as constant as possible. Apparent phalangeal ultrasound transmission velocity (APU) measured in 54 isolated, fresh pig phalanges was shown to be independent of bone mineral density (BMD) measured by SPA. Fastest sound transmission led exclusively through cortical bone so that intertrabecular connectivity in spongious bone could not influen…

AdultMaleAdolescentSwineMiddle fingerBone tissueBone and BonesFingersMetacarpophalangeal JointRheumatologyBone DensityIn vivomedicineAnimalsHumansOsteoporosis PostmenopausalAgedUltrasonographyAged 80 and overBone mineralbusiness.industryUltrasoundAge FactorsReproducibility of ResultsGeneral MedicineAnatomyMiddle AgedPhalanxElasticitymedicine.anatomical_structureMaterial qualityFemaleCortical boneNuclear medicinebusinessClinical Rheumatology
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Treatment of skin swellings with C1-inhibitor concentrate in patients with hereditary angio-oedema.

2008

Background:  Skin swellings are the most frequent symptoms in hereditary angio-oedema (HAE) arising out of C1-inhibitor (C1-INH) deficiency. They may be painful and impact daily activities of patients. Detailed clinical data concerning the treatment of skin swellings by C1-INH concentrate have not been reported yet. Methods:  From 1976 through 2007, a total of 2104 skin-swelling attacks in 47 patients with HAE were treated with the C1-INH concentrate. Time to relief and duration of the swellings were documented during personal interviews using standardized questionnaires. The results were compared with 9046 untreated skin swellings in the same patients. Results:  The first clinical sign of …

AdultMaleAllergymedicine.medical_specialtyHereditary angio-oedemaAdolescentImmunologyC1-inhibitorImmunopathologyImmunology and AllergyMedicineHumansIn patientProspective StudiesChildAgedRetrospective StudiesSkinbiologybusiness.industryAngioedemas HereditaryDrug administrationMiddle Agedmedicine.diseaseTrunkSurgerybiology.proteinFemaleLaryngeal oedemabusinessComplement C1 Inhibitor ProteinAllergy
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Detection of Strands in Native Aortic Valves by Transesophageal Echocardiography

1997

Prevalence and echocardiographic characteristics of strands on the leaflets of native aortic valves were examined. According to our data, the strands we found in 39% of patients are most likely Lambl's excrescences.

AdultMaleAortic valvemedicine.medical_specialtybusiness.industryHeart Valve DiseasesMiddle AgedValvula aorticaDiagnosis Differentialmedicine.anatomical_structureAortic ValveInternal medicinecardiovascular systemmedicineCardiologyHumansFemaleProspective StudiesRadiologyEsophagusCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealAgedThe American Journal of Cardiology
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Absence of cardiovascular autonomic dysfunction and vagal pancreatic impairment in idiopathic achalasia of the oesophagus

2007

Abstract  Extra-oesophageal autonomic dysfunction in idiopathic achalasia is not well documented, due to contradictory results reported. We aimed to study the cardiovascular and pancreatic autonomic function in patients with idiopathic achalasia. Thirty patients with idiopathic achalasia (16M/14F; 34.5 ± 10.8 years) and 30 healthy volunteers (13M/17F; 34.8 ± 10.7 years) were prospectively studied. Age >60 years and conditions affecting results of autonomic evaluation were excluded. Both groups underwent the sham feeding test and plasmatic levels of pancreatic polypeptide (PP) were determined by radioimmunoassay (basal, at 5, 10, 20 and 30 min). Cardiovascular parasympathetic (deep breathing…

AdultMaleAutonomic functionmedicine.medical_specialtyAdolescentPhysiologyDiaphragmatic breathingAchalasiaAutonomic Nervous SystemPancreatic PolypeptideEatingEsophagusInternal medicinemedicineHumansPancreatic polypeptideEndocrine and Autonomic Systemsbusiness.industryGastroenterologyVagus NerveRadioimmunoassayMiddle Agedmedicine.diseaseSham feedingEsophageal AchalasiaBlood pressureTasteAnesthesiaCardiologyMasticationFemaleIdiopathic achalasiabusinessNeurogastroenterology & Motility
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Interchangeability among five devices that measure anterior eye distances.

2014

The aim was to study the interchangeability of various devices that measure anterior chamber depth (ACD) and white-to-white (WTW) distance.Eighty right eyes of eighty patients aged 20 to 40 years were included. Their spherical equivalent ranged from -4.25 to +1.00 dioptres. Each eye's ACD and the WTW distance were measured using the following devices: a Castroviejo surgical calliper, CA-200F Corneal Analyser, Orbscan II, Pentacam HR and IOLMaster 500.The Pentacam HR measured significantly greater ACD (p0.01) than the other two devices, whereas IOLMaster 500 and Orbscan II yielded comparable (p0.01) distances. Nonetheless, in every device comparison, the mean difference was within clinically…

AdultMaleBiometrybusiness.industryAnterior ChamberMeasure (physics)Corneal TopographyReproducibility of ResultsEquipment DesignRefraction OcularRefractive ErrorsInterchangeabilityCorneaOphthalmologyYoung AdultOpticsOptometryMedicineHumansFemaleProspective StudiesbusinessOptometryFollow-Up StudiesClinicalexperimental optometry
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Expression of Bax, a pro-apoptotic member of the Bcl-2 family, in esophageal squamous cell carcinoma

1997

Samples of normal esophageal squamous epithelium (n = 10), severe squamous cell dyplasia (n = 22), carcinoma in situ (n = 15), invasive squamous cell carcinoma (n = 172), lymph-node metastasis (n = 21) and 2 permanent esophageal squamous cell carcinoma cell lines were analyzed immunohistochemically for Bax expression using a polyclonal anti-Bax antibody. Immunostaining was evaluated according to a score system (0–8 points) based on the percentage of positive tumor cells and the relative immunostaining intensity. Cytoplasmatic staining for Bax protein was found uniformly in all cell layers of the normal esophageal squamous epithelium. In contrast, a gradual loss of immunoreactivity for Bax w…

AdultMaleCancer ResearchPathologymedicine.medical_specialtyEsophageal NeoplasmsCellBiologyMetastasisEsophagusProto-Oncogene ProteinsTumor Cells CulturedmedicineHumansEsophagusAgedbcl-2-Associated X ProteinAged 80 and overCarcinoma in situCancerMiddle AgedEsophageal cancermedicine.diseaseSurvival AnalysisNeoplasm Proteinsmedicine.anatomical_structureProto-Oncogene Proteins c-bcl-2OncologyEpidermoid carcinomaCarcinoma Squamous CellRegression AnalysisFemaleCarcinoma in SituImmunostainingInternational Journal of Cancer
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Differences in incidence and survival of oral cavity and pharyngeal cancers between Germany and the United States depend on the HPV-association of th…

2017

Abstract Introduction The epidemiology of squamous cell oral cavity and pharyngeal cancers (OCPC) has changed rapidly during the last years, possibly due to an increase of human papilloma virus (HPV) positive tumors and successes in tobacco prevention. Here, we compare incidence and survival of OCPC by HPV-relation of the site in Germany and the United States (US). Materials and methods Age-standardized and age-specific incidence and 5-year relative survival was estimated using data from population-based cancer registries in Germany and the US Surveillance Epidemiology and End Results (SEER) 13 database. Incidence was estimated for each year between 1999 and 2013. Relative survival for 2002…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPopulationHealthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18]03 medical and health sciencesYoung AdultAll institutes and research themes of the Radboud University Medical Center0302 clinical medicinePharyngeal cancerGermanyEpidemiologySurveillance Epidemiology and End ResultsMedicineHumans030212 general & internal medicineeducationAgededucation.field_of_studyRelative survivalbusiness.industryIncidence (epidemiology)IncidencePharynxPapillomavirus InfectionsCancerPharyngeal NeoplasmsMiddle Agedmedicine.diseaseSurvival AnalysisUnited StatesSurgeryTumor Virus Infectionsmedicine.anatomical_structureOncology030220 oncology & carcinogenesisFemaleMouth NeoplasmsOral SurgerybusinessDemography
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