Search results for "genome"

showing 10 items of 1913 documents

The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild

2013

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.

0106 biological sciencesConservation geneticsMalegenotype phenotype correlationGorillaComputingMilieux_LEGALASPECTSOFCOMPUTINGarginineGenoma humà01 natural sciencesOculocutaneous albinism type 4single nucleotide polymorphismAlbinismegenetic variabilityGorillaInbreedinggenetic conservationGenetics0303 health sciencesGenomebiologyarticlecopy number variationHigh-Throughput Nucleotide SequencingSLC45A2 geneGenomicszygosityOculocutaneous albinismFloquet de neu (Goril·la)AlbinismFemaleBiotechnologyamino acid substitutionResearch ArticleSLC45A2Gorilla gorilla gorillaHeterozygoteAlbinismMolecular Sequence Datacomparative genomic hybridizationgene sequenceConservation010603 evolutionary biology03 medical and health sciencesWestern lowland gorillabiology.animalmedicineGeneticsheterozygosityAnimalsAmino Acid Sequencegene030304 developmental biologygene identificationWhole genome sequencingnonhumanGorilla gorillaMembrane Transport ProteinsSequence Analysis DNA15. Life on landbiology.organism_classificationmedicine.diseaseGenòmicaData_GENERALMutationbiology.proteinGenèticaoculocutaneous albinismglycineMicrosatellite RepeatsBMC Genomics
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The application of the CRISPR-Cas9 genome editing machinery in food and agricultural science: Current status, future perspectives, and associated cha…

2019

The recent progress in genetic engineering has brought multiple benefits to the food and agricultural industry by enhancing the essential characteristics of agronomic traits. Powerful tools in the field of genome editing, such as siRNA-mediated RNA interference for targeted suppression of gene expression and transcription activator-like effector nucleases (TALENs) and zinc-finger nucleases (ZFNs) for DNA repair have been widely used for commercial purposes. However, in the last few years, the discovery of the CRISPR-Cas9 system has revolutionized genome editing and has attracted attention as a powerful tool for several industrial applications. Herein, we review current progresses in the uti…

0106 biological sciencesCrops AgriculturalComputer scienceBioengineeringComputational biology01 natural sciencesApplied Microbiology and Biotechnology03 medical and health sciencesGenome editingRNA interference010608 biotechnologyTranscription Activator-Like Effector NucleasesCRISPRFood IndustryHumans030304 developmental biologyGene Editing0303 health sciencesTranscription activator-like effector nucleasebusiness.industryPlants Genetically ModifiedZinc finger nucleaseZinc Finger NucleasesAgricultureGene TargetingEthical concernsCRISPR-Cas SystemsbusinessGenetic EngineeringBiotechnologyBiotechnology advances
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Nested core collections maximizing genetic diversity in Arabidopsis thaliana.

2004

Summary The successful exploitation of natural genetic diversity requires a basic knowledge of the extent of the variation present in a species. To study natural variation in Arabidopsis thaliana, we defined nested core collections maximizing the diversity present among a worldwide set of 265 accessions. The core collections were generated based on DNA sequence data from a limited number of fragments evenly distributed in the genome and were shown to successfully capture the molecular diversity in other loci as well as the morphological diversity. The core collections are available to the scientific community and thus provide an important resource for the study of genetic variation and its …

0106 biological sciencesDNA PlantArabidopsisSingle-nucleotide polymorphismPlant Science01 natural sciencesGenomePolymorphism Single NucleotideDNA sequencing[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health sciencesArabidopsis[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsGenetic variationGeneticsArabidopsis thalianaComputingMilieux_MISCELLANEOUS030304 developmental biologyGenetic associationGenetics0303 health sciencesGenetic diversitybiologyGenetic VariationCell Biology15. Life on landbiology.organism_classificationPhenotypeEvolutionary biologyhuman activitiesGenome Plant010606 plant biology & botanyThe Plant journal : for cell and molecular biology
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Phylogeography and Molecular Evolution of Potato virus Y

2012

Potato virus Y (PVY) is an important plant pathogen, whose host range includes economically important crops such as potato, tobacco, tomato, and pepper. PVY presents three main strains (PVYO, PVYN and PVYC) and several recombinant forms. PVY has a worldwide distribution, yet the mechanisms that promote and maintain its population structure and genetic diversity are still unclear. In this study, we used a pool of 77 complete PVY genomes from isolates collected worldwide. After removing the effect of recombination in our data set, we used Bayesian techniques to study the influence of geography and host species in both PVY population structure and dynamics. We have also performed selection and…

0106 biological sciencesEvolutionary GeneticsAmino-acid sitesSelective constraintsPotyviruslcsh:Medicine01 natural sciencesAmino-Acid SitesRecombinant strainPlant RNA virusesNegative selectionMaximum-Likelihoodlcsh:Sciencepathologie végétaleSelective ConstraintsPhylogenyGenetics0303 health sciencesCoat proteinMultidisciplinaryNatural selectionVegetal BiologybiologyEcologyGenetic-structurePotyvirusfood and beveragesEuropePhylogeneticsVenous necrosisPhylogeographyPotato virus YBiogeographyVenous NecrosisSequence AnalysisResearch ArticlePlant RNA VirusesGenome ViralMicrobiologyEvolution Molecular03 medical and health sciencesGenetic-StructureMolecular evolutionVirologyMosaic-virus[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyEvolutionary SystematicsBiology030304 developmental biologySolanum tuberosumGenetic diversityEvolutionary BiologyMosaic virusHost (biology)Maximum-likelihoodlcsh:RComputational Biologyvirus à de la pomme de terreBayes Theoremlégumebiology.organism_classificationMutational analysisMosaic-VirusMutational AnalysisEvolutionary EcologyRecombinant StrainNorth Americalcsh:QBiologie végétalePopulation Genetics010606 plant biology & botany
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The genome sequence of the grape phylloxera provides insights into the evolution, adaptation, and invasion routes of an iconic pest

2020

Background: Although native to North America, the invasion of the aphid-like grape phylloxera Daktulosphaira vitifoliae across the globe altered the course of grape cultivation. For the past 150 years, viticulture relied on grafting-resistant North American Vitis species as rootstocks, thereby limiting genetic stocks tolerant to other stressors such as pathogens and climate change. Limited understanding of the insect genetics resulted in successive outbreaks across the globe when rootstocks failed. Here we report the 294-Mb genome of D. vitifoliae as a basic tool to understand host plant manipulation, nutritional endosymbiosis, and enhance global viticulture. Results: Using a combination of…

0106 biological sciencesFil·loxeraPhysiology[SDV]Life Sciences [q-bio]Introduced speciesPlant Science01 natural sciencesGenomeGene duplicationsStructural BiologyVitislcsh:QH301-705.5ComputingMilieux_MISCELLANEOUS2. Zero hunger0303 health scienceseducation.field_of_studyHost plant interactionsGenomeEndosymbiosisbiologyfood and beveragesBiological SciencesBiological EvolutionGeneral Agricultural and Biological SciencesRootstockInfectionDaktulosphaira vitifoliaeBiotechnologyResearch ArticlePopulation010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular BiologyHemiptera03 medical and health sciencesGeneticsInsect pestsAnimalsPlagues d'insectesAdaptationBiological invasionsGenomeseducationPhylloxeraEcology Evolution Behavior and Systematics030304 developmental biologyObligateHuman GenomeViticulturaCell Biology15. Life on landbiology.organism_classificationBiologicalEffectorsClimate Actionlcsh:Biology (General)13. Climate actionEvolutionary biologyArthropod genomesPhylloxeraAdaptationIntroduced SpeciesInsectAnimal DistributionDevelopmental Biology
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High-Quality Genome Assembly and Annotation of the Big-Eye Mandarin Fish (Siniperca knerii)

2020

Abstract The big-eye mandarin fish (Siniperca knerii) is an endemic species of southern China. It belongs to the family Sinipercidae, which is closely related to the well-known North American sunfish family Centrarchidae. Determining the genome sequence of S. knerii would provide a foundation for better examining its genetic diversity and population history. A novel sequenced genome of the Sinipercidae also would help in comparative study of the Centrarchidae using Siniperca as a reference. Here, we determined the genome sequence of S. knerii using 10x Genomics technology and next-generation sequencing. Paired-end sequencing on a half lane of HiSeq X platform generated 56 Gbp of raw data. R…

0106 biological sciencesGene predictionPopulationChinese perchSequence assemblyGenomicsSinipercaQH426-470BiologyGenome sequencing010603 evolutionary biology01 natural sciencesGenome03 medical and health sciencesGenome SizeGeneticsAnimalsSiniperca kneriieducationMolecular BiologyGenome sizeGenetics (clinical)030304 developmental biologyWhole genome sequencing0303 health scienceseducation.field_of_studyGenome assemblyGenome10x GenomicsFishesHigh-Throughput Nucleotide SequencingMolecular Sequence AnnotationGenomicsbiology.organism_classificationGenome ReportEvolutionary biologyG3: Genes|Genomes|Genetics
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Analysis of plant diversity with retrotransposon-based molecular markers

2010

Retrotransposons are both major generators of genetic diversity and tools for detecting the genomic changes associated with their activity because they create large and stable insertions in the genome. After the demonstration that retrotransposons are ubiquitous, active and abundant in plant genomes, various marker systems were developed to exploit polymorphisms in retrotransposon insertion patterns. These have found applications ranging from the mapping of genes responsible for particular traits and the management of backcrossing programs to analysis of population structure and diversity of wild species. This review provides an insight into the spectrum of retrotransposon-based marker syst…

0106 biological sciencesGenetic MarkersGenome evolutionRetroelementsRetrotransposonReviewBiology01 natural sciencesGenome03 medical and health scienceschemistry.chemical_compoundMolecular markerGenetic variationGeneticsGenetics (clinical)Phylogeny030304 developmental biologyGenetics0303 health sciencesGenetic diversityfungifood and beveragesGenetic VariationPlantsMutagenesis InsertionalchemistryGenetic markerEvolutionary biologyBackcrossinghuman activitiesGenome Plant010606 plant biology & botany
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Mutations in voltage-gated sodium channels from pyrethroid resistant salmon lice (Lepeophtheirus salmonis)

2018

BACKGROUND Parasitic salmon lice (Lepeophtheirus salmonis) cause high economic losses in Atlantic salmon farming. Pyrethroids, which block arthropod voltage-gated sodium channels (Nav 1), are used for salmon delousing. However, pyrethroid resistance is common in L. salmonis. The present study characterized Nav 1 homologues in L. salmonis in order to identify channel mutations associated to resistance, called kdr (knockdown) mutations. RESULTS Genome scans identified three L. salmonis Nav 1 homologues, LsNav 1.1, LsNav 1.2 and LsNav 1.3. Arthropod kdr mutations map to specific Nav 1 regions within domains DI-III, namely segments S5 and S6 and the linker helix connecting S4 and S5. The above …

0106 biological sciencesGeneticsMutationGene knockdownPyrethroidbiologySodium channelGeneral Medicinebiology.organism_classificationmedicine.disease_cause01 natural sciencesGenome010602 entomologychemistry.chemical_compoundDeltamethrinchemistryLepeophtheirusInsect Scienceparasitic diseasesmedicineAgronomy and Crop ScienceAllele frequency010606 plant biology & botanyPest Management Science
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The chloroplast genome of the lichen‐symbiont microalga Trebouxia sp. Tr9 (Trebouxiophyceae, Chlorophyta) shows short inverted repeats with a single …

2019

The Trebouxiophyceae is the class of Chlorophyta algae from which the highest number of chloroplast genome (cpDNA) sequences has been obtained. Several species in this class participate in symbioses with fungi to form lichens. However, no cpDNA has been obtained from any Trebouxia lichen-symbiont microalgae, which are present in approximately half of all lichens. Here, we report the sequence of the completely assembled cpDNA from Trebouxia sp. TR9 and a comparative study with other Trebouxio-phyceae. The organization of the chloroplast genome of Trebouxia sp. TR9 has certain features that are unusual in the Trebouxiophyceae and other green algae. The most remarkable characteristics are the …

0106 biological sciencesGeneticsTrebouxiaNuclear genebiology010604 marine biology & hydrobiologyTrebouxiophyceaePlant ScienceAquatic Sciencebiology.organism_classification010603 evolutionary biology01 natural sciencesGenomeIntergenic regionChloroplast DNARRNA OperonViridiplantaeJournal of Phycology
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Phylogenetic and genomic relationships in Setaria italica and its close relatives based on the molecular diversity and chromosomal organization of 5S…

2001

We have analyzed the phylogenetic and genomic relationships in the genus Setaria Beauv. including diploid and tetraploid species, by means of the molecular diversity of the 5S rDNA spacer and chromosomal organization of the 5S and 18S-5.8S-25S rDNA genes. PCR amplification of the 5S rDNA sequences gave specific patterns. All the species studied here share a common band of about 340 bp. An additional band of an approximately 300-bp repeat unit was found for Setaria verticillata and the Chinese accessions of Setaria italica and Setaria viridis. An additional band of 450 bp was found in the sole species Setaria faberii. Fluorescent in situ hybridization was used for physical mapping of the 5S …

0106 biological sciencesGenetics[SDV.GEN]Life Sciences [q-bio]/Genetics0303 health sciencesSetariaGenetic diversitySetaria verticillataPhylogenetic treeSetaria viridis[SDV.GEN] Life Sciences [q-bio]/GeneticsGeneral MedicineBiologybiology.organism_classification01 natural sciencesGenomeADN RIBOSOMIAL03 medical and health sciencesPhylogeneticsGeneticsAgronomy and Crop ScienceRibosomal DNAComputingMilieux_MISCELLANEOUS030304 developmental biology010606 plant biology & botanyBiotechnologyTheoretical and Applied Genetics
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