Search results for "gero"
showing 10 items of 2629 documents
Genetics of longevity. Data from the studies on Sicilian centenarians
2012
Abstract The demographic and social changes of the past decades have determined improvements in public health and longevity. So, the number of centenarians is increasing as a worldwide phenomenon. Scientists have focused their attention on centenarians as optimal model to address the biological mechanisms of "successful and unsuccessful ageing". They are equipped to reach the extreme limits of human life span and, most importantly, to show relatively good health, being able to perform their routine daily life and to escape fatal age-related diseases, such as cardiovascular diseases and cancer. Thus, particular attention has been centered on their genetic background and immune system. In thi…
Pathophysiology of vascular dementia.
2009
The concept of Vascular Dementia (VaD) has been recognized for over a century, but its definition and diagnostic criteria remain unclear.Conventional definitions identify the patients too late, miss subjects with cognitive impairment short of dementia, and emphasize consequences rather than causes, the true bases for treatment and prevention. We should throw out current diagnostic categories and describe cognitive impairment clinically and according to commonly agreed instruments that document the demographic data in a standardized manner and undertake a systematic effort to identify the underlying aetiology in each case.Increased effort should be targeted towards the concept of and criteri…
Report from the second cytomegalovirus and immunosenescence workshop
2011
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.; International audience; The Second International Workshop on CMV & Immunosenescence was held in Cambridge, UK, 2-4th December, 2010. The presentations covered four separate sessions: cytomegalovirus and T cell phenotypes; T cell memory frequency, inflation and immunosenescence; cytomegalovirus in aging, mortality and disease states; and the immunobiology of cytomegalovirus-specific T cells and effects of the virus on vacc…
Pathophysiology of ageing, longevity and age related diseases
2007
Abstract On April 18, 2007 an international meeting on Pathophysiology of Ageing, Longevity and Age-Related Diseases was held in Palermo, Italy. Several interesting topics on Cancer, Immunosenescence, Age-related inflammatory diseases and longevity were discussed. In this report we summarize the most important issues. However, ageing must be considered an unavoidable end point of the life history of each individual, nevertheless the increasing knowledge on ageing mechanisms, allows envisaging many different strategies to cope with, and delay it. So, a better understanding of pathophysiology of ageing and age-related disease is essential for giving everybody a reasonable chance for living a …
Pathophysiology of age-related diseases
2009
Abstract A Symposium regarding the Pathophysiology of Successful and Unsuccessful Ageing was held in Palermo, Italy on 7-8 April 2009. Three lectures from that Symposium by G. Campisi, L. Ginaldi and F. Licastro are here summarized. Ageing is a complex process which negatively impacts on the development of various bodily systems and its ability to function. A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Thus, a better understanding of the pathophysiology of age-related diseases is urgently required to improve our understanding of maintaining good health in the elderly and to program possible therapeutic intervention.
Centenarians and diet: what they eat in the Western part of Sicily.
2012
Abstract This paper pays attention to the modifiable lifestyle factors such as diet and nutrition that might influence life extension and successful ageing. Previous data reported that in Sicily, the biggest Mediterranean island, there are some places where there is a high frequency of male centenarians with respect to the Italian average. The present data show that in Sicani Mountain zone there are more centenarians with respect to the Italian average. In fact, in five villages of Sicani Mountains, there were 19 people with an age range of 100–107 years old from a total population of 18,328 inhabitants. So, the centenarian number was 4.32-fold higher than the national average (10.37 vs. 2.…
Mechanisms of immunosenescence
2009
Abstract On April 7,8, 2009 a Symposium entitled "Pathophysiology of Successful and Unsuccessful Ageing" took place in Palermo, Italy. Here, the lectures of G. Pawelec, D. Dunn-Walters and. G. Colonna-Romano on T and B immunosenescence are summarized. In the elderly, many alterations of both innate and acquired immunity have been described. Alterations to the immune system in the older person are generally viewed as a deterioration of immunity, leading to the use of the catch-all term immunosenescence. Indeed, many immunological parameters are often markedly different in elderly compared to young people, and some, mostly circumstantial, evidence suggests that retained function of both innat…
El afrontamiento del diagnóstico en pacientes y familiares oncológicos
2016
Introducción: La enfermedad oncológica produce un gran impacto emocional en nuestra población, no solo a los pacientes que las sufren sino a todo el entorno. Conocer el grado de afectación de la enfermedad tanto para los pacientes como a los familiares es primordial para el correcto cuidado por el personal sanitario. Pudiendo mejorar el afrontamiento de la enfermedad. Por tanto el presente estudio pretende conocer el grado de afectación del diagnóstico oncológico en pacientes como en familiares, así como conocer los aspectos que favorezcan el mismo.Metodología: Estudio descriptivo, observacional, transversal llevado a cabo en el Consorcio Hospitalario Provincial de Castellón, en 50 paciente…
Análisis de la cultura de seguridad en el ámbito de la identificación del paciente por el alumnado de enfermería egresado de la Universidad
2015
Objetivos: El proceso asistencial supone la existencia de problemas de seguridad que afectan a la calidad de vida y que se incrementan en la ancianidad. El objetivo de este trabajo es analizar la cultura de seguridad de los profesionales de enfermería. Metodología: Se planteó la elaboración de un estudio descriptivo de corte transversal mediante la administración de una encuesta a una muestra de los alumnos/as egresados/as de la facultad en los últimos tres cursos. El cuestionario constaba de 39 ítems de respuesta múltiple estructurado en aspectos profesionales, seguridad del paciente e identificación del paciente. Los datos fueron recopilados en una base de datos Excel y se realizó el anál…
Los paralogismos de la vejez
2015
En este artículo se propone una reflexión en torno al tema del envejecimiento, centrándose en las dificultades metodológicas en cuanto a su definición por grupo etario; las distintas teorías sobre vejez desarrolladas en las ciencias sociales; los ejes simbólicos en torno a los cuales giran los discursos sobre la vejez; y las paradojas en la cuales se ven inmersos aquellos individuos socialmente clasificados como tales y la sociedad misma, nominada ya con el calificativo de envejecida.