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showing 10 items of 7116 documents

Inhibition and Switching in Healthy Aging: A Longitudinal Study

2016

AbstractObjectives: Discrepant findings of age-related effects between cross-sectional and longitudinal studies on executive function (EF) have been described across different studies. The aim of the present study was to examine longitudinal age effects on inhibition and switching, two key subfunctions of EF, calculated from results on the Color Word Interference Test (CWIT). Methods: One hundred twenty-three healthy aging individuals (average age 61.4 years; 67% women) performed the CWIT up to three times, over a period of more than 6 years. Measures of inhibition, switching, and combined inhibition and switching were analyzed. A longitudinal linear mixed effects models analysis was run in…

Malemedicine.medical_specialtyLongitudinal studyNeuropsychological TestsAudiology050105 experimental psychologyHealthy AgingJudgment03 medical and health sciences0302 clinical medicinePredictive Value of TestsColor wordmedicineHumansAttention0501 psychology and cognitive sciencesLongitudinal StudiesHealthy agingAgedGeneral Neuroscience05 social sciencesCognitive flexibilityReproducibility of ResultsMiddle AgedExecutive functionsPredictive valueInhibition PsychologicalPsychiatry and Mental healthClinical PsychologyLinear ModelsMixed effectsFemaleNeurology (clinical)Psychology030217 neurology & neurosurgeryStroop effectJournal of the International Neuropsychological Society
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Serum Dehydroepiandrosterone Sulfate and Incident Depression in the Elderly: The Pro.V.A. Study

2015

Objective: Dehydroepiandrosterone sulfate (DHEAS) appears to have a protective effect against depression, but contrasting findings are available. Therefore, we investigated whether high serum DHEAS levels were associated with any protective effect on incident depression and incident severe depression in a representative group of elderly men and women. Methods: In a population-based cohort longitudinal study in the general community, 789 older participants without depression and cognitive impairment at the baseline were included, among 3,099 screened subjects. Serum DHEAS levels were determined based on blood samples; incident depression and severe depression were diagnosed by means of the G…

Malemedicine.medical_specialtyLongitudinal studyPopulationchemistry.chemical_compoundDehydroepiandrosterone sulfateelderly.Sex FactorsResidence CharacteristicsInternal medicinemedicineHumansLongitudinal StudieseducationDepression (differential diagnoses)AgedProportional Hazards ModelsAged 80 and overPsychiatric Status Rating Scaleseducation.field_of_studyProportional hazards modelDehydroepiandrosterone SulfateDepressionConfoundingPsychiatry and Mental healthEndocrinologychemistryCohortGeriatric Depression ScaleSerum DHEASFemaleGeriatrics and GerontologyPsychology
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A 5-year retrospective longitudinal study on the incidence and the risk factors of osteonecrosis of the jaws in patients treated with zoledronic acid…

2017

Background The aim of this study was to evaluate the incidence and the risk factors of osteonecrosis of the jaw (ONJ) in a group of patients treated with zoledronic acid (ZA) for bone metastases from solid tumors and enrolled in a preventive dental program. Material and Methods This 5-year retrospective longitudinal study included all consecutive oncological patients who underwent at least one infusion with ZA between 2004 and 2011 for bone metastases due to solid neoplasms. Results Of the 156 patients enrolled in the study, 17 developed ONJ (10.89%). At the multivariate analysis, severe periodontal disease (P=0.025), tooth extraction (P<0.0001) and starting the preventive dental program af…

Malemedicine.medical_specialtyLongitudinal studyTime FactorsBone NeoplasmsZoledronic Acid03 medical and health sciences0302 clinical medicinestomatognathic systemRisk FactorsmedicineHumansIn patientLongitudinal StudiesGeneral DentistryAgedRetrospective StudiesBisphosphonate-associated osteonecrosis of the jawBone Density Conservation AgentsDiphosphonatesbusiness.industryIncidence (epidemiology)ResearchIncidenceImidazolesRetrospective cohort study030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseMedically compromised patients in DentistrySurgeryBone Density Conservation Agentsstomatognathic diseasesZoledronic acidOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASSurgeryBisphosphonate-Associated Osteonecrosis of the JawFemaleOsteonecrosis of the jawbusinessmedicine.drugMedicina oral, patologia oral y cirugia bucal
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Clinical indicators of periodontal disease in patients with coronary heart disease : a 10 years longitudinal study

2011

Objectives: There is evidence about a possible relationship existing between periodontal diseases and coronary heart disease. The aim of the present longitudinal study was to investigate the changes in periodontal evolution after etiological periodontal treatment, comparing a healthy control group with another having coronary heart disease. Study Design: The study included initially 55 patients of which 44 finished it. They were placed into two groups: Healthy Control Group (HCG) n =9, and Coronary Heart Disease Group (CHDG) n=35. The gingival level (GL), probing depth (PD), clinical attachment level (CAL), plaque index (PI) and bleeding on probing (BOP) were measured to compare the periodo…

Malemedicine.medical_specialtyLongitudinal studyTime FactorsPlaque indexBleeding on probingDentistryCoronary DiseaseGastroenterologyPeriodontal diseaseInternal medicinemedicineHumansIn patientLongitudinal StudiesPeriodontal IndicesGeneral DentistryPeriodontal Diseasesbusiness.industry:CIENCIAS MÉDICAS [UNESCO]Coronary heart diseaseOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASEtiologyFemaleResearch-ArticleOdontostomatology for the Disabled or Special PatientsSurgeryPeriodontal Indexmedicine.symptombusiness
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Long-term serial kinetics of N-terminal pro B-type natriuretic peptide and carbohydrate antigen 125 for mortality risk prediction following acute hea…

2017

Aim: Baseline values of N-terminal pro B-type natriuretic peptide (NT-proBNP) and carbohydrate antigen 125 (CA125) predict all-cause mortality in acute heart failure (AHF). However, there is limited information about the added prognostic benefit of using longitudinal values, and how this predictive ability is modified when modelling together. The aim of this study was to determine the mutually-adjusted association between the longitudinal trajectories of NT-proBNP and CA125 with all-cause mortality after an episode of AHF. Methods and results: We included 946 consecutive patients discharged for AHF. NT-proBNP and CA125 were measured at each physician-patient encounter (median (interquartile…

Malemedicine.medical_specialtyLongitudinal studyTime Factorsacute heart failuremedicine.drug_class030204 cardiovascular system & hematologyCritical Care and Intensive Care MedicineRisk Assessment03 medical and health sciences0302 clinical medicineInterquartile rangeRisk FactorsInternal medicineCause of DeathNatriuretic Peptide BrainmedicineNatriuretic peptideHumans030212 general & internal medicineMortalitycarbohydrate antigen 125Survival rateCause of deathAgedRetrospective StudiesHeart Failurebusiness.industrylongitudinal studyMembrane ProteinsRetrospective cohort studyGeneral MedicineBrain natriuretic peptidemedicine.diseasePrognosisPeptide FragmentsSurvival RateEndocrinologyB-type natriuretic peptideSpainHeart failureCA-125 AntigenAcute DiseaseCardiologyFemaleCardiology and Cardiovascular MedicinebusinessBiomarkersFollow-Up StudiesEuropean heart journal. Acute cardiovascular care
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Short-Term Effects of Air Pollution on Cardiovascular Hospitalizations in the Pisan Longitudinal Study

2021

Air pollution effects on cardiovascular hospitalizations in small urban/suburban areas have been scantly investigated. Such effects were assessed among the participants in the analytical epidemiological survey carried out in Pisa and Cascina, Tuscany, Italy (2009–2011). Cardiovascular hospitalizations from 1585 subjects were followed up (2011–2015). Daily mean pollutant concentrations were estimated through random forests at 1 km (particulate matter: PM10, 2011–2015

Malemedicine.medical_specialtyLongitudinal studycardiovascular hospitalizationHealth Toxicology and MutagenesisPopulationair pollutionAir pollutionlcsh:Medicinehigh-resolution pollutant estimate010501 environmental sciencesmedicine.disease_cause01 natural sciencesArticleOdds03 medical and health sciences0302 clinical medicineEpidemiologymedicineHumans030212 general & internal medicineLongitudinal Studieshigh-resolution pollutant estimateseducation0105 earth and related environmental scienceseducation.field_of_studyAir Pollutantscase-crossover designbusiness.industrylcsh:RPublic Health Environmental and Occupational HealthEnvironmental Exposuresuburban areassmall citiesmall citiesHospitalizationItalyCardiovascular DiseasesConditional logistic regressionParticulate Matterepidemiologybusinesscardiovascular hospitalizationsDemographyInternational Journal of Environmental Research and Public Health
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Sagittal static imbalance in myelomeningocele patients: improvement in sitting ability by partial and total gibbus resection

2000

The progression of kyphosis in myelomeningocele is independent of skeletal growth and requires early operative correction and stabilization to prevent a loss of sitting ability. In severe cases, only vertebrectomy makes it possible to achieve correction, stability and skin-closure without tension. In 14 patients with myelomeningocele gibbus, kyphectomy was performed, removing two vertebral bodies on average. The average kyphosis angle decreased from 128 degrees to 81 degrees, enabling most of the patients to participate again in social life by restoring wheelchair mobility. Nevertheless, a significantly higher complication rate was found compared to other correctional operations, lengthenin…

Malemedicine.medical_specialtyMeningomyeloceleTime FactorsPostureKyphosisLumbar vertebraeSittingThoracic VertebraemedicineHumansOrthopedics and Sports MedicineKyphosisChildLumbar Vertebraebiologybusiness.industrySoft tissueGibbusmedicine.diseasebiology.organism_classificationSagittal planeOrthopedic Fixation DevicesSurgerymedicine.anatomical_structureWheelchairsThoracic vertebraeVertebrectomyFemaleOriginal ArticleSurgerybusinessFollow-Up StudiesEuropean Spine Journal
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Acute Kidney Injury After Percutaneous Edge-to-Edge Mitral Repair.

2020

BACKGROUND In catheter-based procedures, acute kidney injury (AKI) is a frequent, serious complication ranging from 10% to 30%. In MitraClip (Abbott Vascular, Santa Clara, California), a usually contrast-free procedure, there is scarce data about its real incidence and impact. OBJECTIVES This study aimed to evaluate incidence, predictive factors, and midterm outcomes of AKI in patients with significant mitral regurgitation (MR) undergoing transcatheter valve repair with MitraClip. METHODS A total of 721 patients undergoing MitraClip were included. AKI was defined as an absolute or a relative increase in serum creatinine of >0.3 mg/dl or >= 50%, respectively, or the need for hemodialysis dur…

Malemedicine.medical_specialtyMitral Valve Annuloplastymedicine.medical_treatmentPopulationRenal function030204 cardiovascular system & hematologyoutcomesurologic and male genital diseasesrenal insufficiency03 medical and health sciences0302 clinical medicinePostoperative ComplicationsInterquartile rangeInternal medicinemedicineMitraClipHumans030212 general & internal medicinemitral edge-to-edge repaireducationAgedRetrospective StudiesAged 80 and overMitral regurgitationeducation.field_of_studybusiness.industryMitraClipIncidenceEndovascular ProceduresAcute kidney injuryMitral Valve InsufficiencyAcute Kidney InjuryMiddle AgedMitraClip acute kidney injury mitral edge-to-edge repair mortality outcomes renal insufficiencymedicine.diseasemortalityfemale genital diseases and pregnancy complicationsacute kidney injurySpainCardiologyFemaleHemodialysisCardiology and Cardiovascular MedicineComplicationbusiness
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Factors associated with mild cognitive impairment in a population-based cohort

2017

Il lavoro non prevede abstract

Malemedicine.medical_specialtyMultivariate analysisNeuropsychological Tests030204 cardiovascular system & hematologyMMSECDTSettore MED/13 - Endocrinologia03 medical and health sciencesPopulation based cohortBMI0302 clinical medicineRisk FactorsInternal medicineInternal MedicinemedicineHumansCognitive DysfunctionLongitudinal StudiesSettore MED/49 - Scienze Tecniche Dietetiche ApplicateCognitive impairmentAgedAged 80 and overbusiness.industryMild cognitive impairmentRegression analysisMiddle AgedCholesterolItalyAnkle-brachial indexCardiovascular DiseasesMultivariate AnalysisABCD studyPhysical therapyRegression AnalysisFemalebusiness030217 neurology & neurosurgery
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CA125 outperforms NT-proBNP in acute heart failure with severe tricuspid regurgitation.

2019

In acute heart failure (AHF) with right ventricular dysfunction, the roles of amino-terminal pro-brain natriuretic peptide (NT-proBNP) and carbohydrate antigen 125 (CA125) are poorly understood, and functional tricuspid regurgitation (TR) severity is thought to indicate a poor prognosis. We examined the prognostic abilities of NT-proBNP and CA125 according to TR status among patients with AHF.TR severity was assessed during index hospitalization (108 ± 24 h after admission) and classified as none/trivial, mild, moderate, or severe. Multivariable Cox regression analysis was performed to assess how pre-discharge CA125 and NT-proBNP were associated with long-term all-cause mortality relative t…

Malemedicine.medical_specialtyMultivariate analysismedicine.drug_classRegurgitation (circulation)030204 cardiovascular system & hematologyVentricular Function Left03 medical and health sciences0302 clinical medicineInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideHumanscardiovascular diseases030212 general & internal medicineAgedAged 80 and overHeart FailureEjection fractionProportional hazards modelbusiness.industryMembrane ProteinsStroke VolumeMiddle Agedmedicine.diseasePrognosisPeptide FragmentsTricuspid Valve InsufficiencyHeart failureCA-125 AntigenCardiologyBiomarker (medicine)FemaleCardiology and Cardiovascular MedicineIndex hospitalizationbusinessBiomarkersInternational journal of cardiology
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