Search results for "gras"

QualigrasPhy : déterminants de la variabilité interindividuelle de la perception du gras chez l'homme

2018

Dietary omega 3 fatty acids and metabolic syndrome in the rat retina: consequences on retinal functionality and complications

2014

Dietary omega 3 fatty acids and metabolic syndrome in the rat retina: consequences on retinal functionality and complications. International society for the study of fatty acids and lipids

Actualités en micronutrition : micrunotrition, oméga-3 et diabète

2015

Détection orosensorielle des lipides alimentaires chez la souris : mécanismes impliqués et altérations au cours de l'obésité

2015

Dietary lipids are detected by the gustatory system in rodents and humans. Two candidate lipid-receptors are found in taste buds: CD36, which is involved in the fat taste as shown by studies conducted in our laboratory, and GPR120. Our results show that GPR120 is not directly involved in the gustatory detection of lipids in mice, but could rather be involved in the modulation of the sensitivity for fat. When this gustatory system works properly, food choices can meet the organism’s energy needs. Besides, the pleasure brought by the consumption of palatable foods is satisfied. However, obese people often overconsume energy-dense food. In the central nervous system, perturbations of the rewar…

Monounsaturated fatly acid metabolism and colon cancer cells proliferation : role of Stearoyl-CoA desaturase-1 and effect of conjugated linoleic acid…

2012

Cancer cells adapt their metabolism in response to signals from the microenvironment and proliferation. Thus, MonoUnsaturated Fatty Acid (MUFA) synthesis is increased in colon cancer cells, and associated with increased Stearoyl-CoA Desaturase (SCD) activity, the rate limiting enzyme of MUFA biosynthesis. Polyunsaturated Fatty Acid (PUFA), as isomers of conjugated linoleic acid (CLA), exert inhibitor activity on SCD-1 and have anti-cancer properties, but their mechanisms are not yet clear. In this context, the aim of this work was first to evaluate the role of SCD-1 in the proliferation of colon cancer cells (CCC) and to define the underlying mechanisms. In a second time, we provide new inf…

Impact of a reduction of plasmalogen levels on Muller cell metabolism

2016

Purpose : Retinopathy of Prematurity (ROP) is the leading cause of blindness in premature children resulting from abnormal vascular development. Previous studies have shown that omega-3 polyunsaturated fatty acids (PUFAs) can modulate physiologic and pathologic angiogenesis. Data from our laboratory suggest that plasmalogens, that are phospholipids that concentrate omega-3 PUFAs, are involved in the regulation of post-natal retinal vascular development through the action of a calcium-independent phospholipase A2 (iPLA2) (Saab et al PLoSONE 2014). In the retina, Müller cells are known to play crucial functions in retinal angiogenesis as well as to be rich in plasmalogens and to express phosp…

Plasma omega 3 polyunsaturated fatty acids and macular pigment optical density in subjects at high risk for age-related macular degeneration: the Lim…

2016

This is an abstract that was submitted for the 2016 ARVO Annual Meeting, held in Seattle, Wash., May 1-5, 2016.; Purpose: In numerous epidemiological studies, omega 3 polyunsaturated fatty acids (PUFAs) have been associated with a decreased risk of age-related macular degeneration (AMD). Beyond their structural, functional and neuroprotective roles, omega 3 PUFAs may favor the retinal accumulation of lutein and zeaxanthin and thus increase macular pigment optical density (MPOD). We examined the associations of MPOD with plasma omega 3 PUFAs in subjects with at least one parent affected by neovascular AMD. Methods: The Limpia study is a double-blind, placebo controlled, prospective randomize…

Intérêt d'aménagements paysagers pour la biodiversité : exemple d'ingénierie agroécologique sur le domaine expérimental d'Epoisses (Inra Dijon)

2013

The biodiversity conservation is one of the major agricultural issues of the XXIst century. The intensification of agriculture and the redesign of the agricultural landscape (grouping of fields, …) lead to huge decreases or damages of semi-naturals habitats, known to promote biodiversity at the farm and the landscape scale, and now recognised as “topographic surface equivalence” in France.In the experimental site of Epoisses (INRA of Dijon), a study to design the landscape elements in favour of the biodiversity has been initiated. Improving the management of existing habitats (woods, hedges, ditches, sown grass margin strips), establishing hedges, flower strips, redesigning the field organi…

Effects of biomass, age and functional traits on regrowth of arable weeds after cutting

2008

Conference: 24th German Conference on Weed Biology and Weed ControlLocation: Stuttgart Hohenheim, GERMANYDate: MAR 04-06, 2008; International audience; In sown field margin stripes or pluriannual forage crops, arable weeds are exposed to high competition and regular mowing or hay cutting, to which they may react very differently. A greenhouse experiment permitted to understand some key factors shaping the ability of common arable weeds and forage crops to grow after such cuttings. Even without competition, cutting shoots at 5cm height reduced biomass production of all 10 species studied, but 6 annual broadleaf weeds were much more affected than 2 perennial forage crops (Dactylis, Medicago) …

Assessing non-chemical weeding strategies through mechanistic modelling of blackgrass (Alopecurus myosuroides Huds.) dynamics

2010

 ; Because of environmental and health safety issues, it is necessary to develop strategies that do not rely on herbicides to manage weeds. Introducing temporary grassland into annual crop rotations and mechanical weeding are the two main features that are frequently used in integrated and organic cropping systems for this purpose. To evaluate the contribution of these two factors in interaction with other cropping system components and environmental conditions, the present study updated an existing biophysical model (i.e. AlomySys) that quantifies the effects of cropping system on weed dynamics. Based on previous experiments, new sub-models were built to describe the effects on plant survi…