Search results for "growth"

showing 10 items of 5134 documents

Exploring the anticancer potential of pyrazolo[1,2-a]benzo[1,2,3,4] tetrazin-3-one derivatives: The effect on apoptosis induction, cell cycle and pro…

2013

In order to investigate their anticancer potential, four new pyrazolo[1,2-a]benzo[1,2,3,4]-tetrazinone derivatives, designed through the chemometric protocol VLAK, and three of the most active compounds of the previous series have been evaluated on some cellular events including proliferation, apoptosis induction, and cell cycle. The NCI one dose (10 mu M) screening revealed that the 8,9-di-methyl derivative showed activity against Leukemia (CCRF-CEM) and Colon cancer cell line (COLO 205), reaching 81% and 45% of growth inhibition (GI), respectively. Replacement of the two methyl groups with two chlorine atoms maintained the activity toward Leukemia cell (CCRF-CEM, GI 77%) and selectively e…

VLAK protocolStereochemistryCell Survival3Cell2Pyrazolo[1Antineoplastic AgentsApoptosisCell cycleHeLachemistry.chemical_compoundStructure-Activity RelationshipPyrazolo[12-a]benzo[1234]tetrazinone VLAK protocol Anticancer agents Apoptosis inducers Cell cycleCell Line TumorDrug DiscoverymedicineHumans2-a]benzo[1EC50Cell ProliferationPharmacologybiologyDose-Response Relationship DrugMolecular StructureCell growthOrganic ChemistryApoptosis inducers4]tetrazinoneGeneral MedicineCell cyclebiology.organism_classificationmedicine.diseaseSettore CHIM/08 - Chimica FarmaceuticaLeukemiamedicine.anatomical_structurechemistryApoptosisAnticancer agentsCancer researchGrowth inhibitionHeterocyclic Compounds 3-RingHeLa Cells
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Local tunneling study of three-dimensional order parameter in the pi band of Al-doped MgB2 single crystals

2007

We have performed local tunneling spectroscopy on high quality Mg$_{1-x}$Al$_x$B$_2$ single crystals by means of Variable Temperature Scanning Tunneling Spectroscopy (STS) in magnetic field up to 3 Tesla. Single gap conductance spectra due to c-axis tunneling were extensively measured, probing different amplitudes of the three-dimensional $\Delta_\pi$ as a function of Al content. Temperature and magnetic field dependences of the conductance spectra were studied in S-I-N configuration: the effect of the doping resulted in a monotonous reduction of the locally measured $T_C$ down to 24K for x=0.2. On the other hand, we have found that the gap amplitude shows a maximum value $\Delta_\pi= 2.3$ …

VORTEXSPECTROSCOPYCondensed Matter - SuperconductivitysuperconductivityBORON[PHYS.COND.CM-S]Physics [physics]/Condensed Matter [cond-mat]/Superconductivity [cond-mat.supr-con]Condensed Matter::SuperconductivityDENSITYHIGH-PRESSUREGROWTHSUPERCONDUCTING MGB2MAGNESIUM DIBORIDEScanning Tunneling Spectroscopy; superconductivityScanning Tunneling Spectroscopy
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Transnacionālās uzņēmējdarbības loma jaunattīstības valstīs: Kamerūnas gadījums

2021

Starpnacionālās uzņēmējdarbība ietvaros cilvēki cenšas īstenot uzņēmējdarbības mērķus to valstu starpā, kurās viņi atrodas, mobilizējot abās sabiedrībās pieejamos resursus veidos, kas atbilst viņu uzņēmējdarbības mērķiem. Globalizācijas dēļ cilvēki var atklāt jaunas kultūras, kopienas un iegūt zināšanas. Tajā pašā laikā cilvēki ar uzņēmējdarbības iniciatīvu uzsāk uzņēmējdarbību tīklā starp savu mītnes valsti un saņēmējvalstīm, izmantojot abpusēji pieejamos resursus. Šajā darbā tiek pētīta starpnacionālā uzņēmējdarbība Kamerūnā, lai izprastu tās ietekmi uz uzņēmumu izveidi un ekonomisko ietekmi jaunattīstības valstī. Galvenā uzmanība tiek pievērsta starptautiskai uzņēmējdarbībai Āfrikas jaun…

VadībzinātneEconomic GrowthDeveloping EconomiesCameroonTransnational Entrepreneurship
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Latvijas jaunuzņēmumu panākumu faktori veidojot augstas izaugsmes tehnoloģiju jaunuzņēmumu

2022

Tā kā pārliecinoši lielākā daļa jaunuzņēmumu negūst panākumus, šī maģistra darba autors izvēlējās izpētīt, kādi ir Latvijas jaunuzņēmumu veiksmes faktori augstas izaugsmes tehnoloģiju jaunuzņēmumu izveidē, kas ir šī maģistra darba mērķis. Pētījums tiek veikts, veicot esošās literatūras analīzi, statistisko datu analīzi un kvalitatīvo analīzi, izmantojot Latvijas jaunuzņēmumu dibinātāju padziļinātās intervijas ar identiskiem, atvērtiem jautājumiem. Autors intervēja tikai veiksmīgākos startup dibinātājus Latvijā. Tika intervēti 14 dibinātāji, kuri ir izveidojuši jaunuzņēmumus ar vidējiem ieņēmumiem 35,5 miljoni eiro un vidējo vecumu 6 gadi, un 3 intervēja investorus, kas ir ieguldījuši augsta…

VadībzinātneHigh Growth Technology StartupCritical Success FactorsEntrepreneurshipIT StartupsStartup Success Factors
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Naftas un gāzes rūpniecības ietekmes analīze uz valsts ekonomisko vidi

2020

Valsts, kura ražo un eksportē naftu parasti tiek uzskatīta par attīstības valsti. Kazahstānas Republika ir viena no attīstības valsts piemēriem ar lielām naftas un gāzes rezervēm. Šī darba pirmajās daļās tiek aprakstīta globālās ekonomikas tekošā situācija naftas un gāzes industrijā, un kādu vietu šī nozare ieņem Kazahstānā. Darba autora veiktie pētījumi, iekļauj sevī PESTLE analīzi, kas uzskatāmi parāda naftas un gāzes industrijas ietekmi uz Kazahstānas ekonomiku, ņemot vērā starptautisko korporāciju ietekmi uz tādām nozarēm kā politika, ekonomika, tehnoloģijas un apkārtējā vide. Pētījuma rezultāti attēlo negatīvas un pozitīvas ietekmes faktoru virkni, kuri savukārt var būt paaugstināti va…

Vadībzinātnemultinational corporationsoil and gas industryGDP growthimpact on the national economyPESTLE analysis
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Economic and Psychological Factors in Entrepreneurial Tendency

2011

In the actual context of global economical crisis, the research question we raised was: Which of the personality traits, formerly associated with entrepreneurship, remain sufficiently stable/strong to overcome the negative economic conditions? That was the starting point to propose experimental evaluation of the possible effect of certain factors such as the economical crisis context/information regarding the economy status and the personal perception regarding the money source/value as regards to the tendency of investing in a small business of the youngsters with a high Internal Locus of Control level.

Value (ethics)Economic growthEntrepreneurshipbusiness.industrymedia_common.quotation_subjectContext (language use)Small businessLocus of controlPerceptionEconomicsBig Five personality traitsPositive economicsbusinessResearch questionmedia_commonSSRN Electronic Journal
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Decentralization in Ukraine and Bottom-Up European Integration

2020

Decentralization is one of the most profound reforms undertaken in Ukraine. It includes the voluntary merging of previously independent villages and towns into larger Amalgamated Territorial Communities (ATCs). The European Union strongly supports the reform but does not make Ukraine’s further European integration conditional upon it. In order to study whether decentralization can, nevertheless, contribute to the country’s European integration, this chapter adopts a sociological perspective. It asks whether decentralization has led to an increase in community twinning and participation of Ukrainian communities in transnational municipal networks. It is based on a survey conducted among the …

Value (ethics)Economic growthUkrainianTop-down and bottom-up designDecentralizationlanguage.human_languageOrder (exchange)Political scienceEuropean integrationlanguagemedia_common.cataloged_instanceSociological imaginationEuropean unionmedia_common
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THE THEORETICAL ASPECTS OF WELL-BEING IN THE CONTEXT OF LIFELONG LEARNING

2017

In 2006 the European Parliament and European Union Council has defined eight key competences for lifelong learning, necessary for personal fulfillment and development, active citizenship, social inclusion and employment. Since the economic crisis of 2008, the world is looking for new ways and methods to ensure the well-fare and reformulate the value of human life. Currently at EU level, one of the most important debates closely connected with the basic context of lifelong learning is on the dimensions of life quality.
 
 The desk study deals with the qualitative content analysis of the documents of EU, OECD, data of the projects of Office of National Statistics in Latvia, the U.K.…

Value (ethics)Economic growthbusiness.industryParliamentmedia_common.quotation_subjectLifelong learningContext (language use)Public relationsActive citizenshipPolitical scienceWell-beingmedia_common.cataloged_instancelifelong learning; life quality; well-beingEuropean unionDimension (data warehouse)businessmedia_commonSOCIETY. INTEGRATION. EDUCATION. Proceedings of the International Scientific Conference
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Transition to distributed energy generation in Finland: Prospects and barriers

2015

Abstract Small-scale distributed energy generation is expected to play an important role in helping Finland increase its energy self-sufficiency. However, the overall strategy to date for promoting distributed energy remains unclear. It is not yet well understood which factors promote the growth of the distributed energy sector and what barriers need to be removed. In this article we present the results of a questionnaire directed at a panel of 26 experts from the distributed energy value chain and 15 semi-structured interviews with industry and non-industry representatives. We investigated, from a sociotechnical transition perspective, the possibilities and challenges of the transition to …

Value (ethics)EngineeringEconomic growthRenewable energySociotechnical systembusiness.industryEnergy (esotericism)Institutional changeTransition (fiction)ta1172Future imagesManagement Monitoring Policy and LawGeneral EnergyDistributed energyDistributed generationGrid connectionElectricitybusinessta512Industrial organizationEnergy transitionEnergy policy
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Positive Turn in Elder-Care Workers' Views Toward Telecare Robots.

2022

AbstractRobots have been slowly but steadily introduced to welfare sectors. Our previous observations based on a large-scale survey study on Finnish elder-care workers in 2016 showed that while robots were perceived to be useful in certain telecare tasks, using robots may also prove to be incompatible with the care workers’ personal values. The current study presents the second wave of the survey data from 2020, with the same respondents (N = 190), and shows how these views have changed for the positive, including higher expectations of telecare robotization and decreased concerns over care robots’ compatibility with personal values. In a longitudinal analysis (Phase 1), the positive change…

Value (ethics)General Computer ScienceSocial Psychologymedia_common.quotation_subjectApplied psychologyControl (management)asenteetCompassionvanhustenhuoltohyväksyminen (psykologia)Article03 medical and health sciencesarvot (käsitykset)0302 clinical medicineRobot acceptancehoivatyö030212 general & internal medicineElectrical and Electronic Engineeringmedia_commonCare robotsEthics030504 nursingNurseTelecareSDG 8 - Decent Work and Economic GrowthValueseettisyys/dk/atira/pure/sustainabledevelopmentgoals/decent_work_and_economic_growthHuman-Computer InteractionPhilosophyControl and Systems Engineeringhoitohenkilöstö5141 Sociology8. Economic growthrobotitSurvey data collectionRobotCare work0305 other medical sciencePsychologyWelfareInternational journal of social robotics
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