Search results for "growth"
showing 10 items of 5134 documents
Tulokkaasta tuottavaksi asiantuntijaksi : perehdyttäminen kehittämisen välineenä eräissä suomalaisissa tietoalan yrityksissä
2010
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
Onko urbanisaatio maaseudun turma? : kaupunkien väestönkasvun vaikutukset erityyppisen maaseudun väestökehitykseen Suomessa ajanjaksolla 1990-2015
2018
Kaupungistuminen on edennyt nopeasti Suomessakin, ja samalla maaseutu on menettänyt väestöään ja aktiviteettejaan. Miten urbanisaation eteneminen on vaikuttanut maaseudun kehitykseen? Artikkelin mukaan urbanisaatio levittää kaupunkien ympäristöön sekä ”varjoa” että ”valoa”, mutta ydinmaaseudun ja harvaan asutun maaseudun negatiiviseen kehitykseen se ei ole vaikuttanut. peerReviewed
Prescription opioid use and employment : A nationwide Finnish register study
2021
Background: The secular decline in labor market participation and the concurrent increase in opioid use in many developed countries have sparked a policy debate on the possible connection between these two trends. We examined whether the use of prescription opioids was connected to labor market outcomes relating to participation, employment and unemployment among the Finnish population. Methods: The working-age population (aged 19–64 years) living in Finland during the period 1995–2016 was used in the analyses (consisting of 67 903 701 person-year observations). Lagged values of prescription opioid use per capita were used as the exposure. Instrumental variables (IV) estimation method was u…
Gestions de l'eau et du développement urbain dans l'espace dijonnais :quels modes d'intégration territoriale ?
2006
Urban growth, jointed to technical networks, contributes to human pressure on water resources. In the meantime, the water French policy put management of urban development in accordance with catchments and hydrologic dynamics; that makes districts and intermunicipal groupings adopt new areas and action systems. The urban area of Dijon is located in three catchments and above a wide groundwater. This case shows urban water management gives greater place to precariousness and common character of water resources, even if institutional responses mainly concern town planning regulation.
Les grands types de sols viticoles de Pomerol et Saint-Emilion
1978
<p style="text-align: justify;">Les vins les plus réputés de la région viticole de Pomerol et Saint-Emilion sont produits sur des sols foncièrement différents, dérivant de roches mères présentant une grande diversité.</p><p style="text-align: justify;">Les variations que l'on peut noter d'un cru à l'autre sont liées, non pas aux caractéristiques chimiques de ces sols, mais surtout à leurs propriétés physiques (texture, structure, porosité, perméabilité) avec leurs conséquences sur le mode et la profondeur de l'enracinement.</p><p style="text-align: justify;">+++</p><p style="text-align: justify;">The most famous wines from the wine-growing region of…
Modern Finnish Economic History
2022
The Finnish economy has experienced a relative late growth and catch-up process in relation to many other advanced Western economies. During this growth period, Finland also experienced a rapid structural change from an agrarian society to a developed service society. In a small open economy, the export industries have played a vital role in this development. Over several centuries, the forest industries have had a dominating impact in exports, along with the metal industries; however, the latter, as well as the electronics industry, with Nokia as the flagship company, gained more importance in the late 20th century in aggregate exports. The egalitarian educational system has to a large ext…
Entrepreneurs and Growth : An Option, Obligation or Obsession?
2018
“Growth” as a word carries a positive tone in it; human beings grow and mature, gaining new knowledge and resources, and so do companies. Growth, however, has never been for all. In competitive markets, some grow and others do not—or grow at slower pace than others. Furthermore, growth is a process that strains the capabilities and resources of an individual, company, and its acting entrepreneurs to their extreme. Growth means also learning and leaving behind something learned of possessed before. Growth disrupts the history and path of a single company and its entrepreneur. The text synthetizes the scattered literature in growth and entrepreneurship. A case study shows how growth is viewed…
Are the Growth Standards of the World Health Organization Valid for Spanish Children? The SONEV Study
2021
Background: The use of different growth tables to assess the population's nutritional status has given rise to a series of limitations arising from the lack of consensus and uniform methodological criteria. This leads to a disparity of results that prevent an accurate and reliable diagnosis of whether a child is overweight or obese.Objective: The purpose of this study was to develop growth references for weight, height, and body mass index for Eastern-Spanish children from 6 to 16 years of age.Methods: The final sample used to fit the growth curves was made up of 1,102 observations. The 2007 WHO curves are currently used for Child Health Service Cards. Therefore, to make the comparison of t…
Zarządzanie funkcją środowiskową w rolnictwie - źródło nowych rent gospodarstw rolnych
2016
W Unii Europejskiej ekologizacja rolnictwa stanowi wstępny etap takiej jego transformacji, która umożliwi gospodarstwom rolnym, rozmieszczonym w różnych miejscach przestrzeni europejskiej, trwały udział w kreowaniu zielonego wzrostu. Praca jest próbą odpowiedzi na pytanie: Czy dzięki doskonaleniu zarządzania funkcją środowiskową towarowe gospodarstwa rolne regionu opolskiego mogą przygotować się do wyzwań związanych z gospodarką sieciową i zadań obecnego etapu ich modernizacji? W opracowaniu przedstawiono rolę polityki ekologicznej w definiowaniu obecnego etapu modernizacji gospodarstw rolnych, mechanizmy jej integracji z celami WPR do 2020 r. oraz strategią Europa 2020. Ustalenia te stanow…