Search results for "guidelines"

showing 10 items of 617 documents

Kawasaki disease: guidelines of the Italian Society of Pediatrics, part I - definition, epidemiology, etiopathogenesis, clinical expression and manag…

2018

Abstract The primary purpose of these practical guidelines related to Kawasaki disease (KD) is to contribute to prompt diagnosis and appropriate treatment on the basis of different specialists’ contributions in the field. A set of 40 recommendations is provided, divided in two parts: the first describes the definition of KD, its epidemiology, etiopathogenetic hints, presentation, clinical course and general management, including treatment of the acute phase, through specific 23 recommendations. Their application is aimed at improving the rate of treatment with intravenous immunoglobulin and the overall potential development of coronary artery abnormalities in KD. Guidelines, however, should…

MalePediatricsReviewPediatricsSeverity of Illness Index0302 clinical medicineRetrospective StudieEpidemiology030212 general & internal medicineDisease management (health)Coronary artery abnormalitieChildrenSocieties MedicalRandomized Controlled Trials as TopicPediatriclcsh:RJ1-570Disease ManagementImmunoglobulins IntravenousGeneral MedicinePrognosisSettore MED/38Treatment OutcomeSettore MED/38 - PEDIATRIA GENERALE E SPECIALISTICAItalyMeta-analysisAcute DiseasePractice Guidelines as TopicDisease ProgressionFemaleCoronary artery abnormalitiesAspirin; Children; Coronary artery abnormalities; Intravenous immunoglobulin; Kawasaki disease;Humanmedicine.medical_specialtyPrognosiMucocutaneous Lymph Node SyndromeRisk Assessment03 medical and health sciences030225 pediatricsSeverity of illnessmedicineHumansRisk factorIntravenous immunoglobulinRetrospective Studiesaspirin; children; coronary artery abnormalities; intravenous immunoglobulin; Kawasaki disease; pediatrics perinatology and child healthAspirinKawasaki diseasebusiness.industrylcsh:PediatricsRetrospective cohort studymedicine.diseaseImmunoglobulins IntravenouPediatrics Perinatology and Child Healthperinatology and child healthKawasaki diseaseDifferential diagnosisbusiness
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WAO guideline for the management of hereditary angioedema

2012

Hereditary Angioedema (HAE) is a rare disease and for this reason proper diagnosis and appropriate therapy are often unknown or not available for physicians and other health care providers. For this reason we convened a group of specialists that focus upon HAE from around the world to develop not only a consensus on diagnosis and management of HAE, but to also provide evidence based grades, strength of evidence and classification for the consensus. Since both consensus and evidence grading were adhered to the document meets criteria as a guideline. The outcome of the guideline is to improve diagnosis and management of patients with HAE throughout the world and to help initiate uniform care …

MalePediatricsdiagnosisInternational CooperationAlternative medicinePatient Care PlanningHereditary AngioedemaEcallantidemedicationsPregnancyBradykinin B2 Receptor AntagonistsHealth careWAO GuidelineImmunology and AllergyChildEvidence-Based MedicineRecombinant ProteinsChild PreschoolinternationalPractice Guidelines as TopicHereditary angioedemaFemaleKallikreinsComplement C1 Inhibitor Proteinmanagementmedicine.drugPulmonary and Respiratory Medicinelcsh:Immunologic diseases. Allergymedicine.medical_specialtyEvidence-based practiceImmunologyMEDLINEGuidelinesDiagnosis DifferentialAllergy and ImmunologymedicineHumansddc:610Intensive care medicinetherapybusiness.industryDanazolAngioedemas HereditaryHAESocial SupportGuidelinemedicine.diseasePeptidesbusinesslcsh:RC581-607Rare disease
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Different guidelines for imaging after first UTI in febrile infants: yield, cost, and radiation.

2013

OBJECTIVE: To evaluate the yield, economic, and radiation costs of 5 diagnostic algorithms compared with a protocol where all tests are performed (ultrasonography scan, cystography, and late technetium99dimercaptosuccinic acid scan) in children after the first febrile urinary tract infections. METHODS: A total of 304 children, 2 to 36 months of age, who completed the diagnostic follow-up (ultrasonography, cystourethrography, and acute and late technetium99dimercaptosuccinic acid scans) of a randomized controlled trial (Italian Renal Infection Study 1) were eligible. The guidelines applied to this cohort in a retrospective simulation were: Melbourne Royal Children’s Hospital, National Insti…

MalePediatricsmedicine.medical_specialtyFeverUrinary systemCost-Benefit AnalysisNiceRadiation DosageVesicoureteral refluxlaw.inventionCystographyRandomized controlled triallawmedicineHumansProspective StudiesProspective cohort studycomputer.programming_languagemedicine.diagnostic_testbusiness.industryInfantmedicine.diseaseDimercaptosuccinic acidChild PreschoolPediatrics Perinatology and Child HealthCohortPractice Guidelines as TopicUrinary Tract InfectionsFemalebusinesscomputermedicine.drugFollow-Up StudiesPediatrics
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Diagnostic approach to microcephaly in childhood: a two-center study and review of the literature.

2014

Aim: The aim of this study was to assess the diagnostic approach to microcephaly in childhood and to identify the prevalence of the various underlying causes/disease entities. Method: We conducted a retrospective study on a cohort of 680 children with microcephaly (399 males, 281 females; mean age at presentation 7-8mo, range 1mo-5y) from patients presenting to Charité - University Medicine Berlin (n=474) and University Hospital Dresden (n=206). Patient discharge letters were searched electronically to identify cases of microcephaly, and then the medical records of these patients were used to analyze parameters for distribution. Results: The putative aetiology for microcephaly was ascertain…

MalePediatricsmedicine.medical_specialtyMicrocephalyEye DiseasesGenetic counselingMedizinComorbidityGene mutationEpilepsyDevelopmental NeuroscienceGermanyIntellectual DisabilitymedicineHumansRetrospective StudiesEpilepsybusiness.industryInfantRetrospective cohort studymedicine.diseaseComorbidityChild PreschoolPediatrics Perinatology and Child HealthCohortPractice Guidelines as TopicEtiologyMicrocephalyFemaleNeurology (clinical)businessDevelopmental medicine and child neurology
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Standardized weaning of infants <32 weeks of gestation from continuous positive airway pressure – a feasibility study

2015

The practice of weaning premature infants from continuous positive airway pressure (CPAP) varies considerably and is usually performed without written standards. In this study, the feasibility of a standardized weaning approach was evaluated. In a quasi-experimental design, data from a prospective, post-intervention cohort (n=41) were compared to data from a pre-intervention cohort (n=36). Standardized weaning was feasible but no significant differences in short-term respiratory outcomes were observed. Weaning from CPAP was achieved at 32.1 ± 1.6 (post-intervention) versus 32.5 ± 2.3 weeks (pre-intervention) postmenstrual age. More rigorous, large-scale clinical trials are necessary before …

MalePediatricsmedicine.medical_specialtyTime Factorsmedicine.medical_treatment03 medical and health sciences0302 clinical medicine030225 pediatricsmedicineHumansWeaning030212 general & internal medicineContinuous positive airway pressureContinuous Positive Airway Pressurebusiness.industryInfant NewbornPostmenstrual AgeInfantObstetrics and GynecologyEvidence-based medicineClinical trialPractice Guidelines as TopicPediatrics Perinatology and Child HealthCohortFeasibility StudiesGestationFemalebusinessVentilator WeaningInfant PrematureThe Journal of Maternal-Fetal & Neonatal Medicine
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GOLD 2017 treatment pathways in ‘real life’: An analysis of the DACCORD observational study

2017

Abstract Introduction The 2017 update to the Global Initiative for Obstructive Lung Disease (GOLD) strategy document includes recommendations for treatment intensification or step-down in chronic obstructive pulmonary disease (COPD), although recognises that limited supporting information is available. DACCORD is an ongoing observational, non-interventional study, recruiting patients following COPD maintenance treatment change or initiation, a subset of whom were receiving a long-acting β2-agonist (LABA) plus a long-acting muscarinic antagonist (LAMA) fixed-dose combination (FDC) on entry. Since there were no requirements in terms of prior medication (and no washout before commencing LABA/L…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyExacerbationmedicine.drug_classMuscarinic AntagonistsQuinolonesMaintenance ChemotherapyPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicinePharmacotherapyAdrenal Cortex HormonesGermanyInternal medicineAdministration InhalationmedicineHumansddc:610Longitudinal StudiesProspective Studies030212 general & internal medicineAdrenergic beta-2 Receptor AgonistsAgedCOPDbiologybusiness.industryDisease ManagementMiddle AgedLamabiology.organism_classificationmedicine.diseaseGlycopyrrolateObstructive lung diseaseDrug Combinations030228 respiratory systemIndansPractice Guidelines as TopicCritical PathwaysDisease ProgressionPhysical therapyIndacaterolCorticosteroidDrug Therapy CombinationFemaleObservational studybusinesshormones hormone substitutes and hormone antagonistsmedicine.drugRespiratory Medicine
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Do GOLD stages of COPD severity really correspond to differences in health status?

2003

The purpose of this study was to assess whether different stages of chronic obstructive pulmonary disease (COPD) severity defined according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria correlate with meaningful differences in health status. A total of 381 COPD patients, aged 73+/-6 yrs, were classified in the five GOLD stages. Disease-specific (St George Respiratory Questionnaire (SGRQ)) and generic indexes of health status were measured in all patients. Multivariate analysis of covariance or Kruskal Wallis tests were used to compare health status indexes across the spectrum of GOLD stages of COPD severity. GOLD stages of COPD severity significantly differed…

MalePulmonary and Respiratory Medicinemedicine.medical_specialtyMultivariate analysisPulmonary diseaseGlobal Initiative for Chronic Obstructive Lung Disease guidelineshealth statusComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioSeverity of Illness IndexelderlyHealth StatuPulmonary Disease Chronic ObstructiveSurveys and QuestionnairesInternal medicineSeverity of illnessChronic obstructive pulmonary disease; elderly; Global Initiative for Chronic Obstructive Lung Disease guidelines; health statusmedicineSurveys and QuestionnaireHumansStage (cooking)Multivariate AnalysiRespiratory Function TestAgedCOPDbusiness.industryKruskal–Wallis one-way analysis of varianceChronic obstructive pulmonary diseaseAged; Comorbidity; Female; Humans; Linear Models; Male; Multivariate Analysis; Pulmonary Disease Chronic Obstructive; Respiratory Function Tests; Surveys and Questionnaires; Health Status; Severity of Illness Indexmedicine.diseaseComorbidityObstructive lung diseaseRespiratory Function TestsMultivariate AnalysisLinear ModelsPhysical therapyLinear ModelFemalebusinessHumanEuropean Respiratory Journal
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European Registry on Helicobacter pylori management (Hp-EuReg): patterns and trends in first-line empirical eradication prescription and outcomes of …

2020

ObjectiveThe best approach for Helicobacter pylori management remains unclear. An audit process is essential to ensure clinical practice is aligned with best standards of care.DesignInternational multicentre prospective non-interventional registry starting in 2013 aimed to evaluate the decisions and outcomes in H. pylori management by European gastroenterologists. Patients were registered in an e-CRF by AEG-REDCap. Variables included demographics, previous eradication attempts, prescribed treatment, adverse events and outcomes. Data monitoring was performed to ensure data quality. Time-trend and geographical analyses were performed.Results30 394 patients from 27 European countries were eval…

MaleRegistrieProton Pump InhibitorPractice Patterns0302 clinical medicineClarithromycinProspective StudiesRegistriesPractice Patterns Physicians'[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologybiologyGastroenterologyMiddle AgedAnti-Bacterial Agents3. Good healthEurope030220 oncology & carcinogenesisCombination030211 gastroenterology & hepatologyDrug Therapy CombinationFemalemedicine.drugHumanAdultmedicine.medical_specialtyTRIPLE THERAPY ; QUADRUPLE THERAPY ; CONSENSUS ; INFECTION ; METAANALYSIS ; CLARITHROMYCIN ; GUIDELINES ; RESISTANCE ; ARTICLESettore MED/12 - GASTROENTEROLOGIAFirst lineHelicobacter Infections03 medical and health sciencesDrug TherapyInternal medicineAnti-Bacterial AgentmedicineHumansMedical prescriptionAdverse effectAgedPhysicians'Helicobacter pyloribusiness.industryhelicobacter pylori - treatmentProton Pump InhibitorsAmoxicillinHelicobacter pyloribiology.organism_classificationMetronidazoleProspective StudieConcomitanthelicobacter pyloribusinessHelicobacter Infection[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Under-prescription of statins in patients with non-alcoholic fatty liver disease

2017

Abstract Background and Aim Non-alcoholic fatty liver disease (NAFLD) is a common disease associated with high cardiovascular risk. Management of dyslipidaemia plays a pivotal role in the prevention of CV events and statins have proved to be safe in these patients. However, in everyday clinical practice statin prescription is sometimes limited because of the concern of physicians about side-effects. The aim of the study was to investigate if the presence of NAFLD affects the prescription of lipid-lowering treatment in a large series of patients with cardio-metabolic disorders. Methods and Results Cardiovascular risk and LDL-C targets were defined according to ESC/EAS Guidelines in 605 conse…

MaleSettore MED/09 - Medicina InternaEndocrinology Diabetes and MetabolismMedicine (miscellaneous)Disease030204 cardiovascular system & hematologyEndocrinology0302 clinical medicineDrug PrescriptionNon-alcoholic Fatty Liver DiseaseRisk FactorsCardiovascular DiseaseNutrition and DieteticPractice Patterns Physicians'Nutrition and Dieteticsmedicine.diagnostic_testFatty liverMiddle AgedDiabetes and MetabolismCardiovascular DiseasesPractice Guidelines as TopicCohortUnder-prescriptionFemalelipids (amino acids peptides and proteins)030211 gastroenterology & hepatologyGuideline AdherenceCardiology and Cardiovascular MedicineHumanAdultCardiovascular risk; Non-alcoholic fatty liver disease; Statins; Under-prescription; Medicine (miscellaneous); Endocrinology Diabetes and Metabolism; Nutrition and Dietetics; Cardiology and Cardiovascular Medicinemedicine.medical_specialtyStatinmedicine.drug_classContext (language use)Health Services MisuseDrug Prescriptions03 medical and health sciencesInternal medicinemedicineHumansMedical prescriptionAgedDyslipidemiasCross-Sectional Studiebusiness.industryRisk FactorStatinsStatinnutritional and metabolic diseasesNon alcoholicBiomarkerCholesterol LDLCardiovascular riskmedicine.diseaseCross-Sectional StudiesDyslipidemiaPhysical therapyHydroxymethylglutaryl-CoA Reductase InhibitorHydroxymethylglutaryl-CoA Reductase InhibitorsLipid profilebusinessBiomarkersNutrition, Metabolism and Cardiovascular Diseases
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The use of statins in people at risk of developing diabetes mellitus: Evidence and guidance for clinical practice

2014

Reducing low-density lipoprotein cholesterol (LDL-C) levels using statins is associated with significant reductions in cardiovascular (CV) events in a wide range of patient populations. Although statins are generally considered to be safe, recent studies suggest they are associated with an increased risk of developing Type 2 diabetes (T2D). This led the US Food and Drug Administration (FDA) to change their labelling requirements for statins to include a warning about the possibility of increased blood sugar and HbA1c levels and the European Medicines Agency (EMA) to issue guidance on a small increased risk of T2D with the statin class. This review examines the evidence leading to these clai…

MaleSettore MED/09 - Medicina Internaendocrine system diseasesHSM MEDHydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effectsAnticholesteremic Agents/adverse effectsMedizin1567-5688ComorbidityType 2 diabetesPharmacologyDiabeteHydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosageCardiovascularFasting/bloodCohort StudiesRisk FactorsAnticholesteremic Agents/administration & dosageDiabetes Mellitus Type 2/prevention & controlMulticenter Studies as TopicMedicineT2DDiabetisAnticholesteremic AgentsDiabetesHemoglobin A Glycosylated/analysisFastingGeneral MedicineMiddle AgedDiabetogenicityCVDClinical PracticeObservational Studies as TopicCholesterol LDL/bloodCardiovascular DiseasesPractice Guidelines as Topiclipids (amino acids peptides and proteins)Disease SusceptibilityCardiology and Cardiovascular MedicineRisk assessmentCardiovascular Diseases/prevention & controlCohort studyAdultmedicine.medical_specialtyStatinHydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic usemedicine.drug_classAnticholesteremic Agents/therapeutic useHydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacologyDiabetes Mellitus Type 2/etiologyRisk AssessmentMulticenter Studies as Topic/statistics & numerical dataPrediabetic StateMeta-Analysis as TopicDiabetes mellitusInternal MedicineHumansIntensive care medicinePrediabetic State/epidemiologyGlycated HemoglobinStatins; Diabetes; Diabetogenicity; T2D; Cardiovascular; CVDbusiness.industryCardiovascular Diseases/epidemiologyStatinsStatinnutritional and metabolic diseasesCholesterol LDLmedicine.diseaseComorbidityAnticholesteremic Agents/pharmacologyDiabetes Mellitus Type 2/epidemiologyDiabetes Mellitus Type 2Estatines (Medicaments cardiovasculars)Observational Studies as TopicHydroxymethylglutaryl-CoA Reductase InhibitorsbusinessObservational Study as TopicForecasting
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